A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs

Autor: Andrés Aguilera, Tatiana García-Muse, María L. García-Rubio, Jolanta Polanowska, Nicola O’Reilly, Simon J. Boulton, Ulises Galindo-Diaz, Julie S. Martin

Publikováno v: Cell Reports
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC

Summary Accurate meiotic chromosome segregation critically depends on the formation of inter-homolog crossovers initiated by double-strand breaks (DSBs). Inaccuracies in this process can drive aneuploidy and developmental defects, but how meiotic cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb1d8d10f036e9e9213da361d85d519
http://europepmc.org/articles/PMC6334227