Evaluation of DNA damage in spinal cord and mutagenic effect of a Phα1β recombinant toxin with analgesic properties from the Phoneutria nigriventer spider.

Autor: de Souza AH; Laboratory of Pharmacology and Toxicology, Lutheran University of Brazil (ULBRA), Canoas, Brazil., da Rosa LG; Laboratory of Pharmacology and Toxicology, Lutheran University of Brazil (ULBRA), Canoas, Brazil., Uliano MR; Laboratory of Pharmacology and Toxicology, Lutheran University of Brazil (ULBRA), Canoas, Brazil.; Laboratory of Toxicological Genetics, Lutheran University of Brazil (ULBRA), Canoas, Brazil., da Silva Prado L; Laboratory of Toxicological Genetics, Lutheran University of Brazil (ULBRA), Canoas, Brazil., Ferraz AG; Laboratory of Pharmacology and Toxicology, Lutheran University of Brazil (ULBRA), Canoas, Brazil.; Laboratory of Toxicological Genetics, Lutheran University of Brazil (ULBRA), Canoas, Brazil., Conter LU; Laboratory of Cancer Biology, Lutheran University of Brazil (ULBRA), Canoas, Brazil., Grivicich I; Laboratory of Cancer Biology, Lutheran University of Brazil (ULBRA), Canoas, Brazil., Dallegrave E; Department of Pharmacosciences. Federal, University of Health Sciences of Porto Alegre (UFCSPA), Porto Alegre, Brazil., Gomez MV; Laboratory of Toxins, Institute of Education and Research Santa Casa Belo Horizonte, Belo Horizonte, Brazil., Picada JN; Laboratory of Toxicological Genetics, Lutheran University of Brazil (ULBRA), Canoas, Brazil.

Publikováno v: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2019 May; Vol. 124 (5), pp. 615-620. Date of Electronic Publication: 2018 Dec 13.