Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ulfried Felfer"'
Autor:
Thomas Pabst, Vito LaVopa, Serge H. Boyer, Michel Goldbach, Maria Vasiloiu, André H.M. de Vries, Peter Poechlauer, Christopher Zinganell, Stefan Steinhofer, Peter Hermsen, Ulfried Felfer, Christian Schuster, Scott J. Hecker, Andreas Pelz, Clemens Stueckler, Bas Ritzen, Georg Winkler
Publikováno v:
Organic Process Research & Development. 23:1069-1077
Within this paper, we present the design, development, and scale-up of a process for a continuous Matteson reaction to produce a key intermediate toward the β-lactamase inhibitor vaborbactam. This includes the successful implementation of the contin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0ac2e33ea6b96ffdc34eaeac6616848
https://doi.org/10.1021/acs.oprd.8b00340
https://doi.org/10.1021/acs.oprd.8b00340
Autor:
Kurt Faber, Marian Goriup, Marion F. Koegl, Ulfried Felfer, Ulrike Wagner, Barbara Larissegger-Schnell, Wolfgang Kroutil
Publikováno v:
Advanced Synthesis & Catalysis. 347:951-961
Mandelate racemase (EC 5.1.2.2) is one of the few biochemically well-characterized racemases. The remarkable stability of this cofactor-independent enzyme and its broad substrate tolerance make it an ideal candidate for the racemization of non-natura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::691a501e5bfd667b6201a94ab7101326
https://doi.org/10.1002/adsc.200505012
https://doi.org/10.1002/adsc.200505012
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 16:91-100
Mandelate racemase from Pseudomonas putida ATCC 12633 could be activated in an organic solvent by immobilization in lyotropic liquid crystals (LC). A theoretical model for a system, that consisted of an organic solvent phase to solve the nonpolar sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a61182576a51e6cb115b2953d88b17e
https://doi.org/10.1016/s1381-1177(01)00049-2
https://doi.org/10.1016/s1381-1177(01)00049-2
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 15:213-222
Efficient enzymatic racemization of 2-hydroxy-2-heteroaryl-acetic acid derivatives by mandelate racemase under mild conditions is reported for the first time. (i) Steric limitations for aryl-substituted mandelate derivatives were elucidated to be par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0eaa2f735522f0150628f9d4d5bc455
https://doi.org/10.1016/s1381-1177(01)00035-2
https://doi.org/10.1016/s1381-1177(01)00035-2
Publikováno v:
Tetrahedron. 56:781-790
A chemoenzymatic access to d - or l -sphingosines is presented comprising of a total synthesis of the l - threo -isomer and formal syntheses of the other three isomers. Key to the development of a general synthetic strategy has been the use of enanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e815d13fb081e0dff5a1c187ad62df5
https://doi.org/10.1016/s0040-4020(99)01024-8
https://doi.org/10.1016/s0040-4020(99)01024-8
Autor:
Kurt Faber, C. Jarret, Andrew Willetts, Wolfgang Kroutil, Ingrid Osprian, Romano V. A. Orru, Ulfried Felfer, Ulrike T. Strauss
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 6:555-560
Lyophilized cells of Rhodococcus R 312 (CBS 717.73) can be employed as an easy-to-use biocatalyst for the biocatalytic hydrolysis of nitriles to furnish the corresponding carboxamides or acids on a preparative scale. The following practical aspects a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2b35f3ac1b7b5be9c9f5d03a8c10dce
https://doi.org/10.1016/s1381-1177(99)00009-0
https://doi.org/10.1016/s1381-1177(99)00009-0
Publikováno v:
Tetrahedron: Asymmetry. 10:107-117
Biocatalytic techniques, which lead to the highly efficient transformation of a racemate into a single stereoisomeric product in (theoretically) 100% chemical yield and 100% enantiomeric excess are reviewed and their specific merits and limitations a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71491c062cc4ee025498ce2d7fa1bc63
https://doi.org/10.1016/s0957-4166(98)00490-x
https://doi.org/10.1016/s0957-4166(98)00490-x
Publikováno v:
Journal of Biotechnology. 56:33-40
The production of mandelate racemase [EC 5.1.2.2] from Pseudomonas putida ATCC 12633 was optimized with respect to (i) biomass and (ii) enzyme induction. The dependence of biomass yield and enzyme content on the concentration of carbon-sources (such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19e7a1ad1c32f2321867cd273887be59
https://doi.org/10.1016/s0168-1656(97)00076-x
https://doi.org/10.1016/s0168-1656(97)00076-x
Autor:
Steven R. Thornton, Ulfried Felfer, Stanley M. Roberts, M. Elena Lasterra-Sánchez, Christine J. Todd, Patrick Mayon
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :343-348
Asymmetric epoxidation of a variety of enones 3, 6, 8, 10, 12, 14, 16, 18, 21, 22, 26, 28–30 and 36 gives the corresponding oxiranes in good to excellent yield and optical purity. The oxidation medium consists of basic peroxide or sodium perborate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1030f8e446d1cc917a2965893bce02e0
https://doi.org/10.1039/p19960000343
https://doi.org/10.1039/p19960000343
Autor:
Gerhard Steinbauer, Laurent Lefort, Dirk Sartor, Bert Dielemans, Johannes G. de Vries, André H.M. de Vries, Jeroen A. F. Boogers, Ulfried Felfer, Martina Kotthaus
Publikováno v:
ChemInform. 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bd22ab0e0e6f6b8a5acab4e9ccc5e98
https://doi.org/10.1002/chin.201126237
https://doi.org/10.1002/chin.201126237