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pro vyhledávání: '"Ulf-Eike Werner"'
Publikováno v:
Biochemical and Biophysical Research Communications. 297:1186-1190
The activation of caspases cleaving a plethora of specific substrates is pivotal for initiation as well as execution of apoptosis. The recognition motif for caspases is a tetrapeptide sequence containing an essential aspartic acid residue at the four
Autor:
Silke Lüschen, Dieter Kabelitz, Sabine Adam-Klages, Sandra Ussat, Gudrun Scherer, Marie-Luise Kruse, Ulf-Eike Werner
Publikováno v:
Biochemical and Biophysical Research Communications. 294:672-679
The molecular mechanisms mediating death receptor-induced caspase-independent necrotic cell death are still largely unknown. We have previously reported that NIH3T3 cells are sensitized by caspase inhibition to death receptor-induced cytotoxicity lea