Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Ulf Samuelsson"'
Autor:
Beverley M. Shields, Annelie Carlsson, Kashyap Patel, Julieanne Knupp, Akaal Kaur, Des Johnston, Kevin Colclough, Helena Elding Larsson, Gun Forsander, Ulf Samuelsson, Andrew Hattersley, Johnny Ludvigsson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Maturity Onset Diabetes of the Young (MODY) is a young-onset, monogenic form of diabetes without needing insulin treatment. Diagnostic testing is expensive. To aid decisions on who to test, we aimed to develop a MODY probability calculator f
Externí odkaz:
https://doaj.org/article/7dd0725abec34703999b9a6ee43f95bd
Autor:
Alexander Lind, Eva Freyhult, Felipe de Jesus Cortez, Anita Ramelius, Rasmus Bennet, Peter V. Robinson, David Seftel, David Gebhart, Devangkumar Tandel, Marlena Maziarz, Helena Elding Larsson, Markus Lundgren, Annelie Carlsson, Anna-Lena Nilsson, Malin Fex, Carina Törn, Daniel Agardh, Cheng-ting Tsai, Åke Lernmark, Martina Persson, Gun Forsander, Johnny Ludvigsson, Ulf Samuelsson, Claude Marcus
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105144- (2024)
Summary: Background: Two or more autoantibodies against either insulin (IAA), glutamic acid decarboxylase (GADA), islet antigen-2 (IA-2A) or zinc transporter 8 (ZnT8A) denote stage 1 (normoglycemia) or stage 2 (dysglycemia) type 1 diabetes prior to s
Externí odkaz:
https://doaj.org/article/a4975652334e42b38b70cf638422fb61
Autor:
Lue Ping Zhao, George K. Papadopoulos, Antonis K. Moustakas, George P. Bondinas, Annelie Carlsson, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Martina Persson, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Daniel E. Geraghty, Åke Lernmark
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract HLA-DQ molecules account over 50% genetic risk of type 1 diabetes (T1D), but little is known about associated residues. Through next generation targeted sequencing technology and deep learning of DQ residue sequences, the aim was to uncover
Externí odkaz:
https://doaj.org/article/74813d36caef4a368c740f9032ef0809
The KAG motif of HLA-DRB1 (β71, β74, β86) predicts seroconversion and development of type 1 diabetes
Autor:
Lue Ping Zhao, George K Papadopoulos, Terry P. Lybrand, Antonis K. Moustakas, George P. Bondinas, Annelie Carlsson, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Martina Persson, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Stephen S. Rich, Åke Lernmark
Publikováno v:
EBioMedicine, Vol 69, Iss , Pp 103431- (2021)
Background: HLA-DR4, a common antigen of HLA-DRB1, has multiple subtypes that are strongly associated with risk of type 1 diabetes (T1D); however, some are risk neutral or resistant. The pathobiological mechanism of HLA-DR4 subtypes remains to be elu
Externí odkaz:
https://doaj.org/article/298f1a40bf1e4c889622fbd1193abbd1
Autor:
Tobias Lundgren, Gustaf Reinebo, Markus Jansson Fröjmark, Emil Jäder, Markus Näslund, Per Svartvadet, Ulf Samuelsson, Thomas Parling
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
Recent systematic reviews on the topic of mindfulness- and acceptance-based approaches in sport psychology conclude that there is a need for further trials using a more robust research methodology with direct performance as outcome. Acceptance and Co
Externí odkaz:
https://doaj.org/article/647e471e64d34372b4da583150bcd44d
Autor:
Johnny Ludvigsson, Indusmita Routray, Sriramulu Elluru, Per Leanderson, Helena E Larsson, Björn Rathsman, Ragnar Hanås, Annelie Carlsson, Torben Ek, Ulf Samuelsson, Torun Torbjörnsdotter, Jan Åman, Eva Örtqvist, Karun Badwal, Craig Beam, Rosaura Casas
Publikováno v:
Future Science OA, Vol 6, Iss 7 (2020)
Aim: Double-blind placebo-controlled intervention using glutamic acid decarboxylase (GAD)-alum, vitamin D and Ibuprofen in recent onset Type I diabetes (T1D). Methods: 64 patients (T1D since
Externí odkaz:
https://doaj.org/article/377a1c7fd105422e99f37abf119e20f1
Autor:
Anette Peterson, Lena Hanberger, Karin Akesson, Mats Bojestig, Boel Andersson Gäre, Ulf Samuelsson
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97875 (2014)
Several studies show that good metabolic control is important for children and adolescents with type 1 diabetes. In Sweden, there are large differences in mean haemoglobin A1c (HbA1c) in different hospitals and difficulties implementing national guid
Externí odkaz:
https://doaj.org/article/1ec98c63bf30449cb580c734785fe5ff
Autor:
Emma Hedlund, Johnny Ludvigsson, Helena Elding Larsson, Gun Forsander, Sten Ivarsson, Claude Marcus, Ulf Samuelsson, Martina Persson, Annelie Carlsson
Publikováno v:
Acta Paediatrica. 111:2378-2383
Previous studies have reported an association between month of birth and incidence of type 1 diabetes. Using population-based data, including almost all newly diagnosed children with type 1 diabetes in Sweden, we tested whether month of birth influen
Autor:
George P. Bondinas, Lue Ping Zhao, Antonis K. Moustakas, Johnny Ludvigsson, Ulf Samuelsson, Daniel E. Geraghty, Helena Elding Larsson, Annelie Carlsson, Åke Lernmark, George K. Papadopoulos, William W. Kwok, Ruihan Wang, Chul-Woo Pyo, Claude Marcus, Wyatt C. Nelson
Publikováno v:
Diabetes
HLA-DQA1 and -DQB1 genes have significant and potentially causal associations with autoimmune type 1 diabetes (T1D). To follow up on the earlier analysis on high-risk HLA-DQ2.5 and DQ8.1, the current analysis uncovers seven residues (αa1, α157, α1
Autor:
Ruihan Wang, Åke Lernmark, William W. Kwok, Claude Marcus, George K. Papadopoulos, Antonis K. Moustakas, Wyatt C. Nelson, Chul-Woo Pyo, George P. Bondinas, Lue Ping Zhao, Ulf Samuelsson, Daniel E. Geraghty, Johnny Ludvigsson, Helena Elding Larsson
Publikováno v:
Diabetes
HLA-DQA1 and -DQB1 are strongly associated with type 1 diabetes (T1D), and DQ8.1 and DQ2.5 are major risk haplotypes. Next-generation targeted sequencing of HLA-DQA1 and -DQB1 in Swedish newly diagnosed 1- to 18 year-old patients (n = 962) and contro