Supplementary Materials from A Pragmatic Definition of Therapeutic Synergy Suitable for Clinically Relevant In Vitro Multicompound Analyses

Autor: Mats G. Gustafsson, Rolf Larsson, Ulf Hammerling, Tobias Sjöblom, Peter Nygren, Magnus Åberg, Claes Andersson, Muhammad Kashif

PDF - 105K, This supplement contains three parts. The first presents a motivation/derivation of the cell proliferation model used in the main text. The second gives the theroetical details about the omnibus statistical test used in the main text. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a0174345586d9319a0cb9b1da173c3
https://doi.org/10.1158/1535-7163.22499796

Label free quantification of time evolving morphologies using time-lapse video microscopy enables identity control of cell lines and discovery of chemically induced differential activity in iso-genic cell line pairs

Autor: Obaid Aftab, Mårten Fryknäs, Saadia Hassan, Peter Nygren, Rolf Larsson, Ulf Hammerling, Mats G. Gustafsson

Publikováno v: Chemometrics and Intelligent Laboratory Systems. 141:24-32

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https://doi.org/10.1016/j.chemolab.2014.12.002

NMR Spectroscopy-Based Metabolic Profiling of Drug-Induced Changes In Vitro Can Discriminate between Pharmacological Classes

Autor: Torbjörn Arvidsson, Albert Elmsjö, Obaid Aftab, Mats Gustafsson, Mikael K.R. Engskog, Ulf Hammerling, Curt Pettersson, Jakob Haglöf

Publikováno v: Journal of Chemical Information and Modeling. 54:3251-3258

Drug-induced changes in mammalian cell line models have already been extensively profiled at the systemic mRNA level and subsequently used to suggest mechanisms of action for new substances, as well as to support drug repurposing, i.e., identifying n

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https://doi.org/10.1021/ci500502f

Consumption of red/processed meat and colorectal carcinoma: Possible mechanisms underlying the significant association

Autor: Roland Grafström, Ulf Hammerling, Jonas Bergman Laurila, Nils-Gunnar Ilbäck

Publikováno v: Hammerling, U, Bergman Laurila, J, Grafström, R & Ilbäck, N-G 2016, ' Consumption of red/processed meat and colorectal carcinoma: Possible mechanisms underlying the significant association ', Critical Reviews in Food Science and Nutrition, vol. 56, no. 4, pp. 614-634 . https://doi.org/10.1080/10408398.2014.972498

Epidemiology and experimental studies provide an overwhelming support of the notion that diets high in red or processed meat accompany an elevated risk of developing pre-neoplastic colorectal adenoma and frank colorectal carcinoma (CRC). The underlyi

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http://juuli.fi/Record/0275162416

Dynamic modelling of time series data in nutritional metabonomics — A powerful complement to randomized clinical trials in functional food studies

Autor: D Soeria-Atmadja, Johan Olsson, Jon Gabrielsson, Torbjörn Lundstedt, Mattias Hedenström, Johan Trygg, Ulf Hammerling

Publikováno v: Chemometrics and Intelligent Laboratory Systems. 104:112-120

Functional foods are foods or dietary ingredients that provide a health benefit beyond basic nutrition. A new legislation, known as the Nutrition and Health Claims Regulation, defines the legal framework for such claims within the European Union. Any

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f00474baeec35387d2b26c37164cba3
https://doi.org/10.1016/j.chemolab.2010.07.001