Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Ulf Diederichsen"'
Autor:
Maksim V. Baranov, Frans Bianchi, Anastasiya Schirmacher, Melissa A.C. van Aart, Sjors Maassen, Elke M. Muntjewerff, Ilse Dingjan, Martin ter Beest, Martijn Verdoes, Samantha G.L. Keyser, Carolyn R. Bertozzi, Ulf Diederichsen, Geert van den Bogaart
Publikováno v:
iScience, Vol 11, Iss , Pp 160-177 (2019)
Summary: Antigen presentation to T cells in major histocompatibility complex class II (MHC class II) requires the conversion of early endo/phagosomes into lysosomes by a process called maturation. Maturation is driven by the phosphoinositide kinase P
Externí odkaz:
https://doaj.org/article/777bcaf6cb384f6589d631ee7045013c
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 2136-2144 (2016)
Dynamic combinatorial chemistry (DCC) is an attractive method to efficiently generate libraries of molecules from simpler building blocks by reversible reactions under thermodynamic control. Here we focus on the chemical modification of DNA oligonucl
Externí odkaz:
https://doaj.org/article/b33c1cbaea32401799209e139a0f6c9e
Publikováno v:
Molecules, Vol 25, Iss 4, p 824 (2020)
The fluorescent base guanine analog, 8-vinyl-deoxyguanosine (8vdG), is studied in solution using a combination of optical spectroscopies, notably femtosecond fluorescence upconversion and quantum chemical calculations, based on time-dependent density
Externí odkaz:
https://doaj.org/article/e05318dce90b4ca8a81fac7b7ff48d9c
Molecular architecture with carbohydrate functionalized β-peptides adopting 314-helical conformation
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 948-955 (2014)
Carbohydrate recognition is essential in cellular interactions and biological processes. It is characterized by structural diversity, multivalency and cooperative effects. To evaluate carbohydrate interaction and recognition, the structurally defined
Externí odkaz:
https://doaj.org/article/067c5af894b44193b9c5406c02451607
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 1576-1583 (2012)
The concept of template-assembled synthetic proteins (TASP) describes a central scaffold that predefines the three dimensional structure for diverse molecules linked to this platform. Cyclic β-tripeptides are interesting candidates for use as templa
Externí odkaz:
https://doaj.org/article/c17b22ce7bec42e7acc664b684caf9fa
Publikováno v:
ARKIVOC, Vol 2007, Iss 5, Pp 79-90 (2006)
Externí odkaz:
https://doaj.org/article/c8bf84a522fb47bc9359b927d2d31b76
Publikováno v:
Chemistry – A European Journal
Chemistry-a European journal 29(33), e202300649 (2023). doi:10.1002/chem.202300649
Chemistry-a European journal 29(33), e202300649 (2023). doi:10.1002/chem.202300649
Alpha-Synuclein (α-Synuclein) is a 140 amino acid protein implicated in neurodegenerative disorders known as synucleinopathies, where it accumulates in proteinaceous inclusions in the brain. The normal physiological function of α-Synuclein remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed4509df0b69a14be8b8b65e5128e6d
https://hdl.handle.net/21.11116/0000-000D-4715-C21.11116/0000-000D-4717-A
https://hdl.handle.net/21.11116/0000-000D-4715-C21.11116/0000-000D-4717-A
Autor:
Silan Toy, Jörn Dietz, Peter Naumann, Janina Trothe, Franziska Thomas, Ulf Diederichsen, Claudia Steinem, Andreas Janshoff
Publikováno v:
Chemistry – A European Journal.
Autor:
Ilze Lāce, Sophia Bazzi, Jon Uranga, Anastasiya Schirmacher, Ulf Diederichsen, Ricardo A. Mata, Nadja Anita Simeth
Publikováno v:
ChemBioChem.
Autor:
Sören Rindfleisch, Matthias Krull, Jon Uranga, Tobias Schmidt, Fabian Rabe von Pappenheim, Laura Liliana Kirck, Angeliki Balouri, Thomas Schneider, Ashwin Chari, Ronald Kluger, Gleb Bourenkov, Ulf Diederichsen, Ricardo A. Mata, Kai Tittmann
Publikováno v:
Nature catalysis 5(4), 332-341 (2022). doi:10.1038/s41929-022-00771-w
Nature catalysis 5(4), 332 - 341 (2022). doi:10.1038/s41929-022-00771-w
The origins of enzyme catalysis have been attributed to both transition-state stabilization as well as ground-state destabilization of the substrate. For the latter paradigm
The origins of enzyme catalysis have been attributed to both transition-state stabilization as well as ground-state destabilization of the substrate. For the latter paradigm