Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ulf Boemer"'
Autor:
Rienk Offringa, Catherine Olesch, Frederik Cichon, Mareike Grees, Norbert Schmees, Ulrike Roehn, Florian Prinz, Detlef Stoeckigt, Michael Erkelenz, Thi Thanh Uyen Nguyen, Ulf Boemer, Judith Günther, Marc Kunze, Kirstin Petersen, Dennis Kirchhoff
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/07ab2b5c8fd7488eb234fe061e205932
Autor:
Holger Hess-Stumpp, Marie-Pierre Collin, Stuart Ince, Oliver Politz, Uwe Thuss, Sebastian Bender, Klemens Lustig, Dieter Zopf, Christoph Kneip, Peter Ellinghaus, Dominik Mumberg, Sylvia Grünewald, Ulf Boemer, Charlotte Kopitz, Mélanie Héroult, Karl Ziegelbauer
Publikováno v:
International Journal of Cancer
Aberrant activation in fibroblast growth factor signaling has been implicated in the development of various cancers, including squamous cell lung cancer, squamous cell head and neck carcinoma, colorectal and bladder cancer. Thus, fibroblast growth fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b248e95ce00f38e560a438cac15a23
https://doi.org/10.1002/ijc.32224
https://doi.org/10.1002/ijc.32224
Autor:
Hans Briem, Benjamin Bader, Ulf Boemer, Brice Sautier, N. Bohnke, A. Hilpmann, Nicolas Werbeck, J. Kahmann, Volker Badock, D. Wegener, Knut Eis, J. Schroeder, K. Graham, Dieter Moosmayer, Christian Stegmann, J. Mastouri, K. Petersen, Jörg Weiske, Gerhard Siemeister, Roman C. Hillig, Lars Wortmann, F. von Nussbaum
Publikováno v:
'Proceedings of the National Academy of Sciences of the USA ', vol: 116, pages: 2551-2560 (2019)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America 116(7), 2551-2560 (2019). doi:10.1073/pnas.1812963116
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America 116(7), 2551-2560 (2019). doi:10.1073/pnas.1812963116
Proceedings of the National Academy of Sciences of the United States of America 116(7), 2551 - 2560 (2019). doi:10.1073/pnas.1812963116
Since the late 1980s, mutations in the RAS genes have been recognized as major oncogenes with a high occurren
Since the late 1980s, mutations in the RAS genes have been recognized as major oncogenes with a high occurren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b81d68c52d5b8e57b984ebab279c8e8
https://doi.org/10.1073/pnas.1812963116
https://doi.org/10.1073/pnas.1812963116
Autor:
Steven M. Corsello, Huajia Zhang, Rajesha Rupaimoole, Volker K. Schulze, Clara Lemos, Kasia B. Handing, Douglas L. Orsi, Mrinal Shekhar, Ulrike Sack, Sven Christian, Wilhelm Bone, Ranad Humeidi, William Colgan, Stephanie Hoyt, Andrew Cherniack, Jens Schroder, Stefan Kaulfuss, Krzysztof Brzezinka, Oliver von Ahsen, Anne Mengel, Roman C. Hillig, Detlev Suelzle, Jeremie Mortier, Caitlin Harrington, Rohith Nagari, Justyna Wierzbinska, Derek Chiang, Georg Beckmann, Meagan Olive, Namrata Udeshi, Annie Apffel, Steven Carr, Philip Lienau, Christian Lechner, Ulf Boemer, Alisha Caliman, David McKinney, Florence Wagner, Dominik Mumberg, Marcus Bauser, Andrea Haegebarth, Knut Eis, Ashley Eheim, Todd R. Golub
Publikováno v:
Cancer Research. 82:3588-3588
CSNK1A1 is a serine/threonine kinase involved in multiple cellular processes, including cell division, beta catenin signaling, and TP53 activation. Inhibition of CSNK1A1 has previously been validated as a therapeutic strategy in hematologic malignanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eda27f4110e552a48e195fe20ca593a7
https://doi.org/10.1158/1538-7445.am2022-3588
https://doi.org/10.1158/1538-7445.am2022-3588
Autor:
Timothy A. Lewis, Franziska Siegel, Ulf Boemer, Bethany Kaplan, Heidi Greulich, Franz von Nussbaum, Jens Schroeder, Stephan Siegel, K. Petersen, Ursula Moenning, Mario Hermsen, Florian Prinz, Matthew Meyerson, Sabine Zitzmann-Kolbe, Andrew D. Cherniack, Daniel Korr, Detlev Suelzle, Uwe Eberspaecher, Knut Eis, Keith Graham, Gizem Karsli-Uzunbas
Publikováno v:
Cancer Research. 81:1470-1470
Several targeted therapeutic options exist for non-small cell lung cancer (NSCLC) patients whose tumors harbor mutations of EGFR, including L858R, exon 19 deletions, and the acquired resistance mutation, T790M. However, there is no approved targeted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6267af0034fe42b36e3b59f0f149a452
https://doi.org/10.1158/1538-7445.am2021-1470
https://doi.org/10.1158/1538-7445.am2021-1470
Autor:
Uwe Eberspaecher, Rienk Offringa, Gabriele Leder, Judith Guenther, Roland Neuhaus, Bertolt Kreft, Rafael Carretero, Jeffrey Mowat, Ingo Hartung, Ulf Boemer, Martina Schaefer, Nicolas Werbeck, Mine Oezcan-Wahlbrink, Nuria Aiguabella Font, Sandra Berndt, Barbara Nicke, Corinna Link, Oliver von Ahsen, Mareike Grees, Daniel Baumann
Publikováno v:
Cancer Research. 81:1722-1722
Immune checkpoint blockade using antibodies targeting the cell surface expressed proteins CTLA-4, PD-1 and PD-L1 has revolutionized cancer care and its clinical impact in several indications has prompted a search for complementary immunostimulatory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c95b8a195d1c33ac1081db66cf562fd
https://doi.org/10.1158/1538-7445.am2021-1722
https://doi.org/10.1158/1538-7445.am2021-1722
Autor:
Franziska Siegel, Carl Friedrich Nising, Franz von Nussbaum, Ulf Boemer, Herbert Himmel, Detlev Suelzle, Marcus Bauser, Uwe Eberspaecher, Simon Holton, Joerg Weiske, Florian Prinz, Ralf Lesche, Clara Lemos, Dominik Mumberg, Dieter Moosmayer, Knut Eis, Andrea Haegebarth, Stefan Prechtl, Barbara Nicke, Duy Nguyen, Lars Wortmann, Christian Lechner, Katrin Nowak-Reppel
Publikováno v:
Journal of medicinal chemistry. 62(2)
The availability of a chemical probe to study the role of a specific domain of a protein in a concentration- and time-dependent manner is of high value. Herein, we report the identification of a highly potent and selective ERK5 inhibitor BAY-885 by h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4f7f3e30ce07bd6a816fc7f0903438
https://pubmed.ncbi.nlm.nih.gov/30563338
https://pubmed.ncbi.nlm.nih.gov/30563338
Autor:
Maria Castedo, Ulf Boemer, Dominik Mumberg, Antje Margret Wengner, Mohamed Jemaà, Ariane Abrieu, Laura Senovilla, Ilio Vitale, Stefan Prechtl, Guido Kroemer, Volker Schulze, Karl Ziegelbauer, Lorenzo Galluzzi, Oliver Kepp, Philip Lienau, Gerhard Siemeister, Marcus Koppitz, Michael Brands
Publikováno v:
Cell Death & Differentiation. 20:1532-1545
Monopolar spindle 1 (MPS1), a mitotic kinase that is overexpressed in several human cancers, contributes to the alignment of chromosomes to the metaphase plate as well as to the execution of the spindle assembly checkpoint (SAC). Here, we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a3220c4022a80f768ac0a645caef3f
https://doi.org/10.1038/cdd.2013.105
https://doi.org/10.1038/cdd.2013.105
Autor:
Matthias Friebe, Jan Andersson, Miklós Tóth, Andrea Varrone, Damian Brockschnieder, Ludger Dinkelborg, Balázs Gulyás, Tobias Heinrich, Heribert Schmitt-Willich, Christer Halldin, Sabine Krause, Thomas Dyrks, Ulf Boemer
Publikováno v:
Journal of Nuclear Medicine. 53:1794-1801
Imaging of amyloid-β (Aβ) plaques by PET is more and more integrated into concepts for Alzheimer disease (AD) diagnosis and drug development. The objective of this study was to find novel chemical entities that can be transformed into 18F-labeled A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd70697dfb7355236fe1b9e5902c000
https://doi.org/10.2967/jnumed.112.104810
https://doi.org/10.2967/jnumed.112.104810
Autor:
Franz von Nussbaum, Ulf Boemer, Michael Brands, Wolf-Dietrich Doecke, Nicole Schmidt, Reinhard Nubbemeyer, Holger Steuber, Eleni Lagkadinou, Oliver Politz, Ulrich Bothe, Andreas Steinmeyer, Holger Siebeneicher, Judith Guenther, Antje Margret Wengner, Dominik Mumberg, Lisette Potze, Thomas M. Zollner, Martin Lange, Karl Ziegelbauer
Publikováno v:
Cancer Research. 78:1887-1887
Activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL) is frequently characterized by aberrant activation of both B-Cell Receptor (BCR) & TLR/MYD88 signaling pathways. Constitutive BCR signaling via Bruton's tyrosine kinase (BTK) and PI3K pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed9906a0dd171187036a294f5e6b5afc
https://doi.org/10.1158/1538-7445.am2018-1887
https://doi.org/10.1158/1538-7445.am2018-1887