Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Ulf, Yrlid"'
Autor:
Azar Rezapour, Daniel Rydbeck, Fabian Byvald, Viktor Tasselius, Gustaf Danielsson, Eva Angenete, Ulf Yrlid
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTTailored treatment for patients with rectal cancer requires clinically available markers to predict their response to neoadjuvant treatment. The quantity of tumor-infiltrating lymphocytes (TILs) in pre-operative tumor biopsies has been sugges
Externí odkaz:
https://doaj.org/article/fc313156fb794ada8474f093fe42ca47
Autor:
Sravani Devarakonda, Annika Thorsell, Per Hedenström, Azar Rezapour, Lisen Heden, Sanghita Banerjee, Malin E.V. Johansson, George Birchenough, Amelie Toft Morén, Karin Gustavsson, Viktor Skokic, Victor L. Pettersson, Fei Sjöberg, Marie Kalm, Mohammad Al Masri, Michaela Ekh, Henrik Fagman, Mats Wolving, Rosie Perkins, Rodrigo A. Morales, Francisca Castillo, Eduardo J. Villablanca, Ulf Yrlid, Karin Bergmark, Gunnar Steineck, Cecilia Bull
Publikováno v:
EBioMedicine, Vol 94, Iss , Pp 104691- (2023)
Summary: Background: Radiotherapy is effective in the treatment of cancer but also causes damage to non-cancerous tissue. Pelvic radiotherapy may produce chronic and debilitating bowel symptoms, yet the underlying pathophysiology is still undefined.
Externí odkaz:
https://doaj.org/article/e9705bf6853e4dbbaa1a59fcbdf76691
Autor:
Alaitz Aranburu, Erik Engström, Natalija Gerasimcik, Samuel Alsén, Alessandro Camponeschi, Ulf Yrlid, Ola Grimsholm, Inga-Lill Mårtensson
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immunological memory protects our body from re-infection and it is composed of a cellular and a humoral arm. The B-cell branch with its memory B cells (MBCs), plasma cells and antibodies, formed either in a germinal centre (GC) -dependent or -indepen
Externí odkaz:
https://doaj.org/article/780fd6145b714b46a9ff27077a599e9e
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Rectal cancer constitutes approximately one-third of all colorectal cancers and contributes to considerable mortality globally. In contrast to colon cancer, the standard treatment for localized rectal cancer often involves neoadjuvant chemor
Externí odkaz:
https://doaj.org/article/fb4ca781472941b2899c29022c0bef26
Autor:
Samuel Alsén, Jakob Cervin, Yaxiong Deng, Louis Szeponik, Ulf Alexander Wenzel, Joakim Karlsson, Helena Cucak, Megan Livingston, David Bryder, Qianjin Lu, Bengt Johansson-Lindbom, Ulf Yrlid
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
B cells interact with T follicular helper (Tfh) cells in germinal centers (GCs) to generate high-affinity antibodies. Much less is known about how cognate T–B-cell interactions influence Th cells that enter circulation and peripheral tissues. There
Externí odkaz:
https://doaj.org/article/4d799bf2f9044fdbb729db3bcd5cb042
Autor:
Rathan Joy Komban, Anneli Strömberg, Adi Biram, Jakob Cervin, Cristina Lebrero-Fernández, Neil Mabbott, Ulf Yrlid, Ziv Shulman, Mats Bemark, Nils Lycke
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Gut lumen antigens must be continuously sampled by the immune system to maintain proper immune homeostasis. Here the authors show that activated CCR6+CCR1+GL7- gut B cells retrieve lumen antigens from specialized M cells and transfer them across the
Externí odkaz:
https://doaj.org/article/dfa3b986a6dc4e698df2c098d4517404
Publikováno v:
Clinical and Translational Oncology. 24:1818-1827
Background Tumor-associated macrophages (TAM) are known to facilitate colorectal cancer (CRC) growth. High macrophage infiltration in thymidine phosphorylase (TYMP) expressing CRC may correspond to poor prognosis. The prognostic impact of the express
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T follicular helper (Tfh) cells are a specialized subset of CD4+ T cells that collaborate with B cells to promote and regulate humoral responses. Unlike other CD4+ effector lineages, Tfh cells require interactions with both dendritic cells (DCs) and
Externí odkaz:
https://doaj.org/article/5f57a71a8cc644cea9b87cb8dc098ca2
Autor:
Jakob Cervin, Amberlyn M Wands, Anna Casselbrant, Han Wu, Soumya Krishnamurthy, Aleksander Cvjetkovic, Johanna Estelius, Benjamin Dedic, Anirudh Sethi, Kerri-Lee Wallom, Rebecca Riise, Malin Bäckström, Ville Wallenius, Frances M Platt, Michael Lebens, Susann Teneberg, Lars Fändriks, Jennifer J Kohler, Ulf Yrlid
Publikováno v:
PLoS Pathogens, Vol 14, Iss 2, p e1006862 (2018)
Cholera toxin (CT) enters and intoxicates host cells after binding cell surface receptors via its B subunit (CTB). We have recently shown that in addition to the previously described binding partner ganglioside GM1, CTB binds to fucosylated proteins.
Externí odkaz:
https://doaj.org/article/f798db5d3c714c6f9abd3318d6d329e7
Autor:
Frank, Liang, Lisa M, Nilsson, Fabian, Byvald, Azar, Rezapour, Helena, Taflin, Jonas A, Nilsson, Ulf, Yrlid
Publikováno v:
Cancers. 14(12)
The diversity of T cells in the human liver may reflect the composition of TILs in CRLM. Our ex vivo characterization of CRLM vs. adjacent liver tissue detected CD103+CD39+CD8+ T