Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Ulf, Diczfalusy"'
Autor:
Helena Bergström, Anna Lindahl, Anna Warnqvist, Ulf Diczfalusy, Lena Ekström, Linda Björkhem‐Bergman
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract The 6β‐OH‐cortisol/cortisol ratio (6β‐OHC/C) in urine is an endogenous marker of drug‐metabolizing enzyme cytochrome P450 3A (CYP3A). The primary aim of this single center, prospective, non‐interventional cohort study, was to inv
Externí odkaz:
https://doaj.org/article/e6fd217badb04affa22e05d2e0970d18
Autor:
Hadi Molanaei, Abdul Rashid Qureshi, Olof Heimbürger, Bengt Lindholm, Ulf Diczfalusy, Björn Anderstam, Leif Bertilsson, Peter Stenvinkel
Publikováno v:
BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Recent studies indicate that inflammation may also affect CYP3A4 activity. Associations of CYP3A4-mediated metabolism of quinine, with inflammatory biomarkers were investigated in patients undergoing maintenance hemodialysis (HD).
Externí odkaz:
https://doaj.org/article/86731a31fcfa40b59c03659a4f35c093
Autor:
Aklillu, Eulambius M. Mlugu, Omary M. Minzi, Appolinary A. R. Kamuhabwa, Ulf Diczfalusy, Eleni
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15168
Changes in cortisol and other hormones during pregnancy may alter CYP3A enzymes activity, but data from sub-Saharan Africa are sparse. We investigated the effect of pregnancy and CYP3A5 genotypes on CYP3A enzymes activity using the plasma 4β-hydroxy
Autor:
Eulambius M, Mlugu, Omary M, Minzi, Appolinary A R, Kamuhabwa, Ulf, Diczfalusy, Eleni, Aklillu
Publikováno v:
International journal of molecular sciences. 23(23)
Changes in cortisol and other hormones during pregnancy may alter CYP3A enzymes activity, but data from sub-Saharan Africa are sparse. We investigated the effect of pregnancy and
Autor:
Ingemar Björkhem, Ulf Diczfalusy, Anita Lövgren-Sandblom, Lena Starck, Monica Jonsson, Keri Tallman, Henrik Schirmer, Lilian Bomme Ousager, Peter J. Crick, Yuqin Wang, William J. Griffiths, F. Peter Guengerich
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 6, Pp 1165-1172 (2014)
A new mechanism for formation of 7-ketocholesterol was recently described involving cytochrome P-450 (CYP)7A1-catalyzed conversion of 7-dehydrocholesterol into 7-ketocholesterol with cholesterol-7,8-epoxide as a side product. Some patients with cereb
Externí odkaz:
https://doaj.org/article/576e66e606e24d37898877f880a7b361
Autor:
Eyasu Makonnen, Ulf Diczfalusy, Jürgen Burhenne, Alimuddin Zumla, Abiy Habtewold, Wondwossen Amogne, Getnet Yimer, Eleni Aklillu
Publikováno v:
British Journal of Pharmacology
BACKGROUND AND PURPOSE In TB-HIV co-infection, prompt initiation of TB therapy is recommended but anti-retroviral treatment (ART) is often delayed due to potential drug-drug interactions between rifampicin and efavirenz. In a longitudinal cohort stud
Autor:
Linda Björkhem-Bergman, Ulf Diczfalusy, Anna Lindahl, Lena Ekström, Anna Warnqvist, Helena Bergström
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives
The 6β‐OH‐cortisol/cortisol ratio (6β‐OHC/C) in urine is an endogenous marker of drug‐metabolizing enzyme cytochrome P450 3A (CYP3A). The primary aim of this single center, prospective, non‐interventional cohort study, was to investigate
Autor:
Ulf Diczfalusy, Katarina E. Olofsson, Ann-Margreth Carlsson, Mei Gong, Douglas T. Golenbock, Olav Rooyackers, Urban Fläring, Harry Björkbacka
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 11, Pp 2258-2264 (2009)
During screening of genes upregulated by lipopolysaccharide (LPS; endotoxin) treatment of bone marrow-derived mouse macrophages, it was unexpectedly found that cholesterol 25-hydroxylase (Ch25h) was strongly upregulated. Treatment of macrophages with
Externí odkaz:
https://doaj.org/article/ac61fb491b374c4d8ec7877b8dbfa180
Autor:
Steve Meaney, Maura Heverin, Ute Panzenboeck, Lena Ekström, Magnus Axelsson, Ulla Andersson, Ulf Diczfalusy, Irina Pikuleva, John Wahren, Wolfgang Sattler, Ingemar Björkhem
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 4, Pp 944-951 (2007)
Recently, we demonstrated a net blood-to-brain passage of the oxysterol 27-hydroxycholesterol corresponding to 4–5 mg/day. As the steady-state levels of this sterol are only 1–2 μg/g brain tissue, we hypothesized that it is metabolized and subse
Externí odkaz:
https://doaj.org/article/29855b943bef4c258274a21859ee3155
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121984 (2015)
PURPOSE:To investigate the effect of vitamin D3 on hepatic Cytochrome P450 enzyme (CYP) 3A4 in patients with abnormal glucose regulation using the endogenous marker 4β-hydroxycholesterol (4β-OHC):cholesterol ratio. METHODS:The present study took ad
Externí odkaz:
https://doaj.org/article/1c9533fc4f524062bf6e0230b38978a5