Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Uksha Saini"'
Autor:
Alessandro Canella, Mykyta Artomov, Aleksandr Ukhatov, Sakthi Rajendran, Phillip Perez, Uksha Saini, Jack Hedberg, Kevin Cassady, Prajwal Rajappa
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 3, Pp 200861- (2024)
High-grade gliomas (HGGs) and glioblastomas (GBMs) are the most aggressive and lethal brain tumors. The current standard of care (SOC) includes gross safe surgical resection followed by chemoradiotherapy. The main chemotherapeutic agents are the DNA-
Externí odkaz:
https://doaj.org/article/eba8ac1afd6b42618a79843c161da767
Autor:
Yeaseul Kim, Uksha Saini, Doyeon Kim, Ilse Hernandez-Aguirre, Jack Hedberg, Alexia Martin, Xiaokui Mo, Timothy P. Cripe, James Markert, Kevin A. Cassady, Ravi Dhital
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMalignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas with unacceptably low cure rates occurring often in patients with neurofibromatosis 1 defects. To investigate oncolytic Herpes Simplex Virus (oHSV) as an immunother
Externí odkaz:
https://doaj.org/article/5f74ff6d85764633914ea8330bf8e162
Autor:
Uksha Saini, Brentley Q. Smith, Kalpana Deepa Priya Dorayappan, Ji Young Yoo, G. Larry Maxwell, Balveen Kaur, Ikuo Konishi, David O’Malley, David E. Cohn, Karuppaiyah Selvendiran
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-5 (2023)
Externí odkaz:
https://doaj.org/article/9e8be0d153694a1fa8fe12a2fe3e034b
Autor:
Uksha Saini, Brentley Q. Smith, Kalpana Deepa Priya Dorayappan, Ji Young Yoo, G. Larry Maxwell, Balveen Kaur, Ikuo Konishi, David O’Malley, David E. Cohn, Karuppaiyah Selvendiran
Publikováno v:
Journal of Ovarian Research, Vol 15, Iss 1, Pp 1-13 (2022)
Abstract Background Ovarian clear cell carcinoma (OCCC) accounts for approximately 8–10% of epithelial ovarian cancers in the United States. Although it is rare, OCCC usually presents with treatment challenges and the overall prognosis is far worse
Externí odkaz:
https://doaj.org/article/1d1a1f67412e49b5982bf5b24cbbe75b
Autor:
Chun-Yu Chen, Mohammed G Ghonime, Uksha Saini, Michael C Kelly, Justin C Roth, Pin-Yi Wang, Katherine Miller, Ilse Hernandez-Aguirre, Yeaseul Kim, Xiaokui Mo, Joseph R Stanek, Tim Cripe, Elaine Mardis, Kevin A Cassady
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/000e2ddeb46142639945f4ab424b5abd
Autor:
Balveen Kaur, Ji Young Yoo, Zhongming Zhao, Guangsheng Pei, Karuppaiyah Selvendiran, Yuanqing Yan, Anil K. Sood, Zahid H. Siddik, Guangan He, David E. Cohn, Puneet Modgil, Uksha Saini, Valerie Chapa, Bangxing Hong
Purpose:Here we investigated the impact of oncolytic herpes simplex virus (HSV) treatment on cisplatin sensitivity of platinum-resistant ovarian cancer, and the impact of the combination on immunotherapy.Experimental Design:Therapeutic efficacy of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a67b841f77d945ff6b40acd41baff1
https://doi.org/10.1158/1078-0432.c.6529923.v1
https://doi.org/10.1158/1078-0432.c.6529923.v1
Autor:
Balveen Kaur, Karuppaiyah Selvendiran, Jianying Zhang, Timothy P. Cripe, Kellie S. Rath, Uksha Saini, Pin-Yi Wang, Ji Young Yoo, Chelsea Bolyard
Supplementary Figure and Table Legends. Supplementary legends for figures and tables characterizing patient ascites samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653c5e463e5c009adeaa4d7bc22657ed
https://doi.org/10.1158/1078-0432.22457486
https://doi.org/10.1158/1078-0432.22457486
Autor:
Balveen Kaur, Karuppaiyah Selvendiran, Jianying Zhang, Timothy P. Cripe, Kellie S. Rath, Uksha Saini, Pin-Yi Wang, Ji Young Yoo, Chelsea Bolyard
Purpose: Novel therapeutic regimens are needed to improve dismal outcomes associated with late-stage ovarian cancer. Oncolytic viruses are currently being tested in patients with ovarian cancer. Here, we tested the therapeutic efficacy of combining d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5baf7a0adb8767e51d08e45ddfb546
https://doi.org/10.1158/1078-0432.c.6523592.v1
https://doi.org/10.1158/1078-0432.c.6523592.v1
Autor:
Karuppaiyah Selvendiran, David E. Cohn, Paul J. Goodfellow, Beth Y. Karlan, Jenny Lester, Raleigh D. Kladney, Jason Bice, Ross A. Wanner, Kristin Bixel, John J. Wallbillich, Shan Naidu, Adrian A. Suarez, Uksha Saini
Role of STAT3 in high-grade serous carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926520b2e3b6b615d22283e84174f23e
https://doi.org/10.1158/0008-5472.22417608
https://doi.org/10.1158/0008-5472.22417608
Autor:
Karuppaiyah Selvendiran, David E. Cohn, Paul J. Goodfellow, Beth Y. Karlan, Jenny Lester, Raleigh D. Kladney, Jason Bice, Ross A. Wanner, Kristin Bixel, John J. Wallbillich, Shan Naidu, Adrian A. Suarez, Uksha Saini
The initial molecular events that lead to malignant transformation of the fimbria of the fallopian tube (FT) through high-grade serous ovarian carcinoma (HGSC) remain poorly understood. In this study, we report that increased expression of signal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f80fef7698636d5b3a64935f7a2774
https://doi.org/10.1158/0008-5472.c.6509886.v1
https://doi.org/10.1158/0008-5472.c.6509886.v1