APOE4 and Infectious Diseases Jointly Contribute to Brain Glucose Hypometabolism, a Biomarker of Alzheimer's Pathology: New Findings from the ADNI.

Autor: Rajendrakumar AL; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, North Carolina, United States of America., Arbeev KG; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, North Carolina, United States of America., Bagley O; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, North Carolina, United States of America., Duan M; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, North Carolina, United States of America., Yashin AI; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, North Carolina, United States of America., Ukraintseva S; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, North Carolina, United States of America.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Oct 01. Date of Electronic Publication: 2024 Oct 01.

Is being overweight a causal factor in better survival among the oldest old? a Mendelian randomization study.

Autor: Duan H; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, United States., Arbeev K; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, United States., Holmes R; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, United States., Bagley O; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, United States., Wu D; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, United States., Akushevich I; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, United States., Schupf N; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, United States., Yashin A; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, United States., Ukraintseva S; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, United States.

Publikováno v: Frontiers in aging [Front Aging] 2024 Sep 20; Vol. 5, pp. 1442017. Date of Electronic Publication: 2024 Sep 20 (Print Publication: 2024).

Frailty Index as a Major Indicator of Aging Processes and Mortality in Elderly: Results From Analyses of the National Long Term Care Survey Data

Autor: Kulminski, A., Yashin, A., Akushevich, I., Ukraintseva, S., Land, K., Arbeev, K., Manton, K.

To better understand mortality change with age capturing the variability in individuals' rates of aging, we performed comprehensive analysis of statistical properties of a cumulative index of age-associated disorders (deficits), called a "frailty ind

Externí odkaz: http://arxiv.org/abs/q-bio/0509038

Associations of infections and vaccines with Alzheimer's disease point to a role of compromised immunity rather than specific pathogen in AD.

Autor: Ukraintseva S; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA. Electronic address: svo@duke.edu., Yashkin AP; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA. Electronic address: apy4@duke.edu., Akushevich I; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA., Arbeev K; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA., Duan H; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA., Gorbunova G; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA., Stallard E; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA., Yashin A; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.

Publikováno v: Experimental gerontology [Exp Gerontol] 2024 Jun 01; Vol. 190, pp. 112411. Date of Electronic Publication: 2024 Apr 02.

Genome-Wide Epistatic Network Analyses of Semantic Fluency in Older Adults.

Autor: Tan Q; Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, 5230 Odense, Denmark.; Unit of Human Genetics, Department of Clinical Research, University of Southern Denmark, 5230 Odense, Denmark., Li W; Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, 5230 Odense, Denmark., Nygaard M; Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, 5230 Odense, Denmark., An P; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Feitosa M; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Wojczynski MK; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Zmuda J; Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA., Arbeev K; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NA 27708, USA., Ukraintseva S; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NA 27708, USA., Yashin A; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NA 27708, USA., Christensen K; Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, 5230 Odense, Denmark., Mengel-From J; Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, 5230 Odense, Denmark.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 May 11; Vol. 25 (10). Date of Electronic Publication: 2024 May 11.