Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ukrae H. Cho"'
Autor:
Ukrae H Cho, Martin W Hetzer
Publikováno v:
eLife, Vol 12 (2023)
During apoptosis, caspases degrade 8 out of ~30 nucleoporins to irreversibly demolish the nuclear pore complex. However, for poorly understood reasons, caspases are also activated during cell differentiation. Here, we show that sublethal activation o
Externí odkaz:
https://doaj.org/article/a7e127185a764db1b9b9f920070569c1
Multiomics atlas-assisted discovery of transcription factors enables specific cell state programming
Autor:
H. Kay Chung, Cong Liu, Eduardo Casillas, Brent Chick, Bryan Mcdonald, Jun Wang, Peixiang He, Ming Sun, Shixin Ma, Qiyuan Yang, Dan Chen, Filipe Hoffmann, Siva Karthik Varanasi, Victoria Tripple, Yuqing Hang, Ukrae H. Cho, Josephine Ho, April Williams, Yingxiao Wang, Diana Hargreaves, Susan M. Kaech, Wei Wang
Publikováno v:
bioRxiv
The same types of cells can assume diverse states with varying functionalities. Effective cell therapy can be achieved by specifically driving a desirable cell state, which requires the elucidation of key transcription factors (TFs). Here, we integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa410dfe3083f8823ac951d14b75dd94
https://doi.org/10.1101/2023.01.03.522354
https://doi.org/10.1101/2023.01.03.522354
Autor:
Martin W. Hetzer, Ukrae H. Cho
During programmed cell death, caspases degrade 7 out of ~30 nucleoporins (Nups) to irreversibly demolish the nuclear pore complex (NPC). However, for poorly understood reasons, caspases are also activated in differentiating cells in a non-apoptotic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82349572f52efecb805910d49a1b6e7d
https://doi.org/10.1101/2021.08.31.458302
https://doi.org/10.1101/2021.08.31.458302
Autor:
Martin W. Hetzer, Ukrae H. Cho
Publikováno v:
Neuron
In recent years, the nuclear pore complex (NPC) has emerged as a key player in genome regulation and cellular homeostasis. New discoveries have revealed that the NPC has multiple cellular functions besides mediating the molecular exchange between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb485ae70f2908a3f0f0071f698397d4
https://pubmed.ncbi.nlm.nih.gov/32553207
https://pubmed.ncbi.nlm.nih.gov/32553207