Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Uki Yamashita"'
Publikováno v:
Fisheries Science. 78:717-724
In a search for new antitumor drugs, we collected 334 species of marine algae from the Japanese coastline and screened these for tumor necrosis factor-alpha (TNF-α) production-promoting activity in an in vitro assay with the mouse macrophage-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0806c7573bc1a0ac21bb3eb56311a03
https://doi.org/10.1007/s12562-012-0476-6
https://doi.org/10.1007/s12562-012-0476-6
Autor:
Junko Noguchi, Uki Yamashita, Hidetada Matsuoka, Yasuhiro Yoshida, Junichi Tsukada, Ning Ding, Tsutomu Sugiura
Publikováno v:
Cancer. 117:2735-2746
BACKGROUND: Human T-cell leukemia is an aggressive malignancy of T lymphocytes. T-cell leukemia has a very poor prognosis, even with intensive chemotherapy, indicating the need for development of new drugs to treat the disease. Triterpenoid cucurbita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d7b95f0d53cdb3c64afe204cd462b23
https://doi.org/10.1002/cncr.25711
https://doi.org/10.1002/cncr.25711
Autor:
Nobuyuki Yanagihara, Susumu Ueno, Hajime Hori, Yoshiteru Nakano, Yasuhiro Yoshida, Naoki Kunugita, Uki Yamashita, Toru Ishidao, Yukiko Fueta, Tsutomu Sugiura, Jiqin Liu
Publikováno v:
International Immunopharmacology. 9:433-438
1-Bromopropane (1-BP) has been widely used as an alternative to ozone-depleting chlorofluorocarbons in various industries. Although the neurotoxicity of 1-BP has been recently reported, there is little information about the effect of 1-BP on the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2b52a2fe45181d6b7880b0eba35346
https://doi.org/10.1016/j.intimp.2009.01.007
https://doi.org/10.1016/j.intimp.2009.01.007
Publikováno v:
The Journal of Immunology. 179:6596-6603
IL-23 is a heterodimeric cytokine composed of a unique p19 subunit and a common p40 subunit is shared with IL-12. IL-23 promotes the inflammatory response by inducing the expansion of CD4+ cells producing IL-17. The regulation of p19 gene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e91672fe3da4746bb18b9ecbe446c9
https://doi.org/10.4049/jimmunol.179.10.6596
https://doi.org/10.4049/jimmunol.179.10.6596
Publikováno v:
European Journal of Immunology. 37:2185-2195
We have previously reported that peritoneal and splenic macrophages from Th2-dominant BALB/c mice produced higher amounts of prostaglandin (PG) E2 than cells from C57BL/6 mice. In this study, we investigated how macrophages from BALB/c mice acquire t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7075b5bbe7524287bea23509224be133
https://doi.org/10.1002/eji.200737041
https://doi.org/10.1002/eji.200737041
Publikováno v:
Human Reproduction. 22:1801-1809
BACKGROUND: The invasion of first trimester extravillous trophoblast (EVT) to decidua is an important event in placentation. Leukemia inhibitory factor (LIF) is an essential factor for mouse implantation, and it is reported that LIF may be involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec063fd24f5711324f466a1ce6b906b
https://doi.org/10.1093/humrep/dem125
https://doi.org/10.1093/humrep/dem125
Ameliorative effect of pioglitazone on seizure responses in genetically epilepsy-susceptible EL mice
Publikováno v:
Brain Research. 1102:175-178
Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, delayed the development of seizure responses and mildly shortened the duration of convulsion of genetically epileptic EL mice. mRNA levels of IL-1beta, IL-6 and TNF-alpha befor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb66887be17f263a3ed8d69af25188d
https://doi.org/10.1016/j.brainres.2006.04.108
https://doi.org/10.1016/j.brainres.2006.04.108
Publikováno v:
Journal of UOEH. 28:265-275
Recent studies have shown that cytokines and cyclooxygenase (COX)-2 are up-regulated in the brain of human epilepsy patients and animal models of epilepsy. We investigated the effect of inflammatory responses induced by intramuscular injection of tur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af380c02f536af95d7e0dfe664a9ecd
https://doi.org/10.7888/juoeh.28.265
https://doi.org/10.7888/juoeh.28.265
Autor:
Sadatoshi Tsuji, Yasuhiro Yoshida, Akio Suzumura, Etsushi Kuroda, Kazumasa Okada, Uki Yamashita
Publikováno v:
Journal of Neuroimmunology. 159:48-54
The effects of interferon (IFN)-beta used for treatment of multiple sclerosis (MS) on the central nervous system (CNS) have not yet been elucidated. The effect of IFN-beta and IFN-gamma on astrocytes as the major component of the CNS was investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4490be7389ea5c41213ecfecfb7c9974
https://doi.org/10.1016/j.jneuroim.2004.09.013
https://doi.org/10.1016/j.jneuroim.2004.09.013
Publikováno v:
Journal of UOEH. 27:1-10
In previous papers we reported that endocrine disrupters (EDs) such as diethyl stilbesterol (DES), 4,4'-isopropylidene diphenol (Bisphenol A : BPA), bis (2-ethylhexyl) phthalate (EHP) and p-nonylphenol (NP) stimulated proliferative responses and cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39270116cab4e647967689e87191d4b8
https://doi.org/10.7888/juoeh.27.1_1
https://doi.org/10.7888/juoeh.27.1_1