Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Uk Yeol Moon"'
Autor:
SeonJu Park, Raju Das, Nguyen Xuan Nhiem, Sung Baek Jeong, Minuk Kim, Dongguk Kim, Hye In Oh, Su-Hyeon Cho, Oh-Bin Kwon, Jae-Hyeog Choi, Chul Soon Park, Song-Rae Kim, Uk Yeol Moon, Boksik Cha, Dong Kyu Choi, Sungwoo Lee, Wan Namkung, Joohan Woo, Yohan Seo
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Anoctamin 1 (ANO1), a drug target for various cancers, including prostate and oral cancers, is an intracellular calcium-activated chloride ion channel that plays various physiopathological roles, especially in the induction of cancer growth and metas
Externí odkaz:
https://doaj.org/article/253af63eabeb4b5a869570c1e0770388
Autor:
Sung Baek Jeong, Raju Das, Dong-Hyun Kim, Sion Lee, Hye In Oh, Sungwoo Jo, Yechan Lee, Jeongdong Kim, SeonJu Park, Dong Kyu Choi, Uk Yeol Moon, Oh-bin Kwon, Wan Namkung, Sungwoo Lee, Byoung Chul Cho, Joohan Woo, Yohan Seo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113373- (2022)
Anoctamin 1 (ANO1) is a calcium-activated chloride channel found in various cell types and is overexpressed in non-small cell lung cancer (NSCLC), a major cause of cancer-related mortality. With the rising interest in development of druggable compoun
Externí odkaz:
https://doaj.org/article/0d7d8a2863c942b9a4c38ca89e6a8cbc
Autor:
Louis T. Dang, Katarzyna M. Glanowska, Philip H. Iffland II, Allan E. Barnes, Marianna Baybis, Yu Liu, Gustavo Patino, Shivanshi Vaid, Alexandra M. Streicher, Whitney E. Parker, Seonhee Kim, Uk Yeol Moon, Frederick E. Henry, Geoffrey G. Murphy, Michael Sutton, Jack M. Parent, Peter B. Crino
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
mTORopathies are a heterogeneous group of neurological disorders characterized by malformations of cortical development (MCD), enhanced cellular mechanistic target of rapamycin (mTOR) signaling, and epilepsy that results from mutations in mTOR pathwa
Externí odkaz:
https://doaj.org/article/53413016f1094d83a21051ee639df779
Autor:
Jae-Keun Cho, Myoung Woo Kim, Ick Soo Choi, Uk Yeol Moon, Min-Ji Kim, Insuk Sohn, Seonwoo Kim, Han-Sin Jeong
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background The prognostic role of neutrophil-to-lymphocyte ratio (NLR) has been proposed in head and neck squamous cell carcinoma (HNSCC). However, it is currently unclear which cutoff values of NLR could consistently and independently diffe
Externí odkaz:
https://doaj.org/article/1a625bde6570412b8ffead5f1bdd8065
Autor:
Yohan Seo, Sung Baek Jeong, Joo Han Woo, Oh-Bin Kwon, Sion Lee, Hye In Oh, Sungwoo Jo, Seon Ju Park, Wan Namkung, Uk Yeol Moon, Sungwoo Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7100 (2021)
Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-related mortality; thus, therapeutic targets continue to be developed. Anoctamin1 (ANO1), a novel drug target considered for the treatment of NSCLC, is a Ca2+-activated chlorid
Externí odkaz:
https://doaj.org/article/5ab6197f920e4700b1f2c35c6e81ca4b
Autor:
Raehee Park, Uk Yeol Moon, Jun Young Park, Lucinda J. Hughes, Randy L. Johnson, Seo-Hee Cho, Seonhee Kim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Failure of the ependymal cell layer that lines the ventricular surfaces of the brain can result in fetal hydrocephalus. Park et al. reveal a role for the Hippo pathway gene Yap in the generation of ependymal cells, and show that suppression of Yap is
Externí odkaz:
https://doaj.org/article/c946f2033a91434ead953a458b67b434
Autor:
Jae-Keun Cho, Gil Joon Lee, Hae-Dong Kim, Uk Yeol Moon, Min-Ji Kim, Seonwoo Kim, Kwan-Hyuck Baek, Han-Sin Jeong
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203758 (2018)
PURPOSE:The prognostic impact of circulating tumor cells (CTC) on disease recurrence, progression and survivals in patients with head and neck squamous cell carcinoma (HNSCC) has not been adequately described. The objective of this study was to deter
Externí odkaz:
https://doaj.org/article/a48f4a64cdf042ed87454a48cdaff1dc
Autor:
Uk Yeol Moon, Jun Young Park, Raehee Park, Jennifer Y. Cho, Lucinda J. Hughes, James McKenna III, Laura Goetzl, Seo-Hee Cho, Peter B. Crino, Michael J. Gambello, Seonhee Kim
Publikováno v:
Cell Reports, Vol 12, Iss 6, Pp 965-978 (2015)
Tuberous sclerosis complex (TSC) is associated with neurodevelopmental abnormalities, including defects in neuronal migration. However, the alterations in cell signaling mechanisms critical for migration and final positioning of neurons in TSC remain
Externí odkaz:
https://doaj.org/article/bee4fb14053240e5aa1dd547177e74e5
Autor:
Insuk Sohn, Uk Yeol Moon, Ick Soo Choi, Seonwoo Kim, Min-Ji Kim, Jae-Keun Cho, Han-Sin Jeong, Myoung Woo Kim
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
BMC Cancer
BMC Cancer
Background The prognostic role of neutrophil-to-lymphocyte ratio (NLR) has been proposed in head and neck squamous cell carcinoma (HNSCC). However, it is currently unclear which cutoff values of NLR could consistently and independently differentiate
Autor:
Lucinda Hughes, Jun Young Park, Seo-Hee Cho, Raehee Park, Randy L. Johnson, Seonhee Kim, Uk Yeol Moon
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications
Nature Communications
Timely generation and normal maturation of ependymal cells along the aqueduct are critical for preventing physical blockage between the third and fourth ventricles and the development of fetal non-communicating hydrocephalus. Our study identifies Yap