Heat Shock Factor 1 Governs Sleep-Wake Cycles Across Species.

Autor: Yamazaki S, Valekunja UK, Chen-Roetling J, Reddy AB

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 17. Date of Electronic Publication: 2024 Nov 17.

Circadian regulation of lung repair and regeneration.

Autor: Naik A, Forrest KM, Paul O, Issah Y, Valekunja UK, Tang SY, Reddy AB, Hennessy EJ, Brooks TG, Chaudhry F, Babu A, Morley M, Zepp JA, Grant GR, FitzGerald GA, Sehgal A, Worthen GS, Frank DB, Morrisey EE, Sengupta S

Publikováno v: JCI insight [JCI Insight] 2024 Mar 08; Vol. 9 (5). Date of Electronic Publication: 2024 Mar 08.

Mechanisms and physiological function of daily haemoglobin oxidation rhythms in red blood cells.

Autor: Beale AD; MRC Laboratory of Molecular Biology, Cambridge, UK., Hayter EA; Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Crosby P; MRC Laboratory of Molecular Biology, Cambridge, UK., Valekunja UK; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Edgar RS; Department of Infectious Diseases, Imperial College London, London, UK., Chesham JE; MRC Laboratory of Molecular Biology, Cambridge, UK., Maywood ES; MRC Laboratory of Molecular Biology, Cambridge, UK., Labeed FH; Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, UK., Reddy AB; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Wright KP Jr; Department of Integrative Physiology, Sleep and Chronobiology Laboratory, University of Colorado Boulder, Boulder, CO, USA., Lilley KS; Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, UK., Bechtold DA; Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Hastings MH; MRC Laboratory of Molecular Biology, Cambridge, UK., O'Neill JS; MRC Laboratory of Molecular Biology, Cambridge, UK.

Publikováno v: The EMBO journal [EMBO J] 2023 Oct 04; Vol. 42 (19), pp. e114164. Date of Electronic Publication: 2023 Aug 09.

Single-cell transcriptomics and cell-specific proteomics reveals molecular signatures of sleep.

Autor: Jha PK; Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Valekunja UK; Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Ray S; Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, 502285, Telangana, India., Nollet M; Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Imperial College London, South Kensington Campus, London, SW7 2AZ, UK., Reddy AB; Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. areddy@cantab.net.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. areddy@cantab.net.

Publikováno v: Communications biology [Commun Biol] 2022 Aug 19; Vol. 5 (1), pp. 846. Date of Electronic Publication: 2022 Aug 19.

Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells.

Autor: Ch R; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.; School of Biological Sciences, Queen's University Belfast, Belfast, BT9 5DL, UK., Rey G; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.; Unilabs Genetics Laboratory, 1003, Lausanne, Switzerland., Ray S; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, PA, 19104, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, 502285, Telangana, India., Jha PK; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, PA, 19104, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Driscoll PC; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK., Dos Santos MS; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK., Malik DM; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, PA, 19104, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Lach R; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.; Department of Oncology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK., Weljie AM; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, PA, 19104, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., MacRae JI; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK., Valekunja UK; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, PA, 19104, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Reddy AB; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, PA, 19104, USA. areddy@cantab.net.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. areddy@cantab.net.; Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. areddy@cantab.net.; Chronobiology and Sleep institute (CSI), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. areddy@cantab.net.

Publikováno v: Nature communications [Nat Commun] 2021 Jan 15; Vol. 12 (1), pp. 377. Date of Electronic Publication: 2021 Jan 15.