Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ujwal Dahal"'
Publikováno v:
Melanoma Research. 29:382-389
The development of immunotherapy has improved the treatment of melanoma; however, resistance and frequent recurrence persist and remain a major problem. N-methyladenosine (mA) is the most abundant epitranscriptomic mark on mRNA and is essential for v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f236be0b8c3989796bd7bc2d3c72d3c2
https://doi.org/10.1097/cmr.0000000000000580
https://doi.org/10.1097/cmr.0000000000000580
Autor:
Guibin Jiang, Xiu-Jie Wang, Ya-Juan Hao, Hai-Li Ma, Xiao-Li Ping, Hailin Wang, Samir Adhikari, Yong-Liang Zhao, Hui-Ying Sun, Yu-Sheng Chen, Xing Wang, Bao-Fa Sun, Ang Li, Qi Zhou, Chun-Min Huang, Ujwal Dahal, Weiyi Lai, Yun-Gui Yang, Ying Yang, Wen Xiao, Niu Huang
Publikováno v:
Molecular Cell. 61:507-519
The regulatory role of N(6)-methyladenosine (m(6)A) and its nuclear binding protein YTHDC1 in pre-mRNA splicing remains an enigma. Here we show that YTHDC1 promotes exon inclusion in targeted mRNAs through recruiting pre-mRNA splicing factor SRSF3 (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d892c4f5897d47bbd6deff2fe278f53f
https://doi.org/10.1016/j.molcel.2016.01.012
https://doi.org/10.1016/j.molcel.2016.01.012
Autor:
Yue Shi, Weiping Yuan, Samir Adhikari, Xiaofan Zhu, Xiao-Min Lou, Xinquan Wang, Ujwal Dahal, Lu Wang, Yong-Liang Zhao, Xin Yang, Jun Huang, Xi Liu, Ang Li, Yun-Gui Yang, Ying Yang, Yu-Sheng Chen, Wenjia Wang, Wen Xiao, Ying Lv, Xu Zhao, Xiao-Li Ping, Jannie M. Rendtlew Danielsen, Bao-Fa Sun, Feng Liu, Tao Cheng
Publikováno v:
Cell Research
The methyltransferase like 3 (METTL3)-containing methyltransferase complex catalyzes the N6-methyladenosine (m6A) formation, a novel epitranscriptomic marker; however, the nature of this complex remains largely unknown. Here we report two new compone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53308dcee20440b84fd6d523dd50f4ab
https://doi.org/10.1038/cr.2014.3
https://doi.org/10.1038/cr.2014.3
Publikováno v:
Cancer Research. 78:3323-3323
Melanoma is the sixth most common cancer in the USA. Introduction of BRAF inhibitors and advances in cancer immunotherapy has greatly improved treatment of melanoma, however, the problem of tumour relapse and therapy resistance persists. Better under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89c11ca517f061316ee746e45a7aa67a
https://doi.org/10.1158/1538-7445.am2018-3323
https://doi.org/10.1158/1538-7445.am2018-3323