Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Ujjini H, Manjunatha"'
Autor:
Ryan Chan, Christian Shema Mugisha, Vorada Chuenchob, Stephanie A. Moquin, Ujjini H. Manjunatha, Nadine Jarrousse, Vineet D. Menachery, Xuping Xie, Erika L. Flannery, Richard T. Eastman
Publikováno v:
SLAS Discovery, Vol 29, Iss 8, Pp 100189- (2024)
Over the past 25 years, the global community has faced challenges posed by three distinct outbreaks of coronaviruses including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and seve
Externí odkaz:
https://doaj.org/article/d6e6474e81d84cbb9f2bab4c34ca05be
Autor:
Paul Kelly, William A Petri, Rashidul Haque, Ibrahim A Khalil, Lynn Barrett, Tom Kennedy, Timothy Wells, Christopher D Huston, James Platts-mills, Grace S Yang, Richard Omore, Ian H Gilbert, Sumiti Vinayak, Boris Striepen, Ujjini H Manjunatha, Wesley C Van Voorhis, Samuel L M Arnold, Beatriz Baragana, Frederick S Buckner, Jeremy D Burrows, Maria A Caravedo, Ryan Choi, Robert K M Choy, Eugenio de Hostos, Thierry Diagana, Suzanne Duce, Matthew A Hulverson, Pui-Ying Iroh Tam, Minju Kim, Poonum Korpe, Benoît Laleu, Diana Lalika, Fabrice Laurent, Case W McNamara, Marvin J Meyers, Roberta M O’Connor, Kayode K Ojo, Philipp Olias, Nede Ovbiebo, Mattie C Pawlowic, Gladys Queen, Divya Rao, Kevin Reed, Michael W Riggs, Jennifer L Roxas, Adam Sateriale, Deborah A Schaefer, L David Sibley, Jonathan M Spector, Chris Tonkin, Timilehin E Toye, Saul Tzipori, A Clinton White
Publikováno v:
BMJ Global Health, Vol 8, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/540e409047fd43baae051b1737c1bbc5
Autor:
Srinivasa P.S. Rao, Ujjini H. Manjunatha, Sebastian Mikolajczak, Paul G. Ashigbie, Thierry T. Diagana
Publikováno v:
Trends in Parasitology. 39:260-271
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::392b0bfd3c940f70c2e3497f6ff2abba
https://doi.org/10.1016/j.pt.2023.01.010
https://doi.org/10.1016/j.pt.2023.01.010
Autor:
Paul G Ashigbie, Susan Shepherd, Kevin L Steiner, Beatrice Amadi, Natasha Aziz, Ujjini H Manjunatha, Jonathan M Spector, Thierry T Diagana, Paul Kelly
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009057 (2021)
Cryptosporidium is a widely distributed enteric parasite that has an increasingly appreciated pathogenic role, particularly in pediatric diarrhea. While cryptosporidiosis has likely affected humanity for millennia, its recent "emergence" is largely t
Externí odkaz:
https://doaj.org/article/2b0571b14ff849bb96c349c92fc27a13
Autor:
Ujjini H. Manjunatha, Christel Brunschwig, Mathew Njoroge, Srinivasa P. S. Rao, Nina Lawrence, Dale Taylor, Rudolf Müller, Kelly Chibale, Paul M. Njaria, Renier van der Westhuyzen, Vinayak Singh, Leslie J. Street, Amanda Mabhula, Atica Moosa, Digby F. Warner, Denis Ngumbu Muhunga, Paul W. Smith
Publikováno v:
Journal of Medicinal Chemistry. 64:9444-9457
Screening of a library of small polar molecules against Mycobacterium tuberculosis (Mtb) led to the identification of a potent benzoheterocyclic oxime carbamate hit series. This series was subjected to medicinal chemistry progression underpinned by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f22b2b0b4cd9366307e089958a09622f
https://doi.org/10.1021/acs.jmedchem.1c00707
https://doi.org/10.1021/acs.jmedchem.1c00707
Autor:
Ujjini H. Manjunatha, Natko Nuber, Cynthia L. Chappell, Wilbur H. Chen, Rajiv S. Jumani, Jay Parthiban Lakshman, Richa Chandra, Natasha Aziz, Dean Wetty, Thierry T. Diagana, Johanne Blais, Hanns-Christian Tillmann, Florencia Segal, Christian Ostermeier
Publikováno v:
ACS Infectious Diseases
Cryptosporidiosis is a leading cause of moderate-to-severe diarrhea in low- and middle-income countries, responsible for high mortality in children younger than two years of age, and it is also strongly associated with childhood malnutrition and grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8baea2ea3108dd8cfa33ea2b1aa8ae2c
https://doi.org/10.1021/acsinfecdis.1c00057
https://doi.org/10.1021/acsinfecdis.1c00057
Autor:
Suresh B Lakshminarayana, Helena I M Boshoff, Joseph Cherian, Sindhu Ravindran, Anne Goh, Jan Jiricek, Mahesh Nanjundappa, Amit Nayyar, Meera Gurumurthy, Ramandeep Singh, Thomas Dick, Francesca Blasco, Clifton E Barry, Paul C Ho, Ujjini H Manjunatha
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105222 (2014)
PA-824 is a bicyclic 4-nitroimidazole, currently in phase II clinical trials for the treatment of tuberculosis. Dose fractionation pharmacokinetic-pharmacodynamic studies in mice indicated that the driver of PA-824 in vivo efficacy is the time during
Externí odkaz:
https://doaj.org/article/7f9d4e061d1d44e1bb837ce762cb14e3
Autor:
Renier, van der Westhuyzen, Amanda, Mabhula, Paul M, Njaria, Rudolf, Müller, Denis, Ngumbu Muhunga, Dale, Taylor, Nina, Lawrence, Mathew, Njoroge, Christel, Brunschwig, Atica, Moosa, Vinayak, Singh, Srinivasa P S, Rao, Ujjini H, Manjunatha, Paul W, Smith, Digby F, Warner, Leslie J, Street, Kelly, Chibale
Publikováno v:
Journal of medicinal chemistry. 64(13)
Screening of a library of small polar molecules against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03d111d78c2e649bf21f94024eb5cf31
https://pubmed.ncbi.nlm.nih.gov/34138573
https://pubmed.ncbi.nlm.nih.gov/34138573
Autor:
Jen Southern, Maria Jose Lafuente-Monasterio, Pottage John C, Caitlin Taylor, William W. Hope, Srinivasa P. S. Rao, Didier Leroy, Jennifer Keiser, Sarah Cook, Clifton E. Barry, John P. Overington, Paul Herrling, Shyam Sundar, Olena Moshynets, David Horn, Lynn L. Silver, Valerie Mizrahi, Manu De Rycker, Isabela Ribeiro, Thomas Spangenberg, Ujjini H. Manjunatha, Nathalie Gobeau, Paul D. Leeson, Jacquin C. Niles, Nicholas J. White, Kevin D. Read, Susan Wyllie, Timothy J. Miles, Richard Amewu, Ian H. Gilbert, Frederick S. Buckner, Wesley C. Van Voorhis, James S. McCarthy, Paul G. Wyatt, Jennifer Herrmann, Michael A. J. Ferguson, Bree B. Aldridge
Publikováno v:
ACS Infectious Diseases
ACS infectious diseases
ACS INFECTIOUS DISEASES
ACS infectious diseases
ACS INFECTIOUS DISEASES
In May 2019, the Wellcome Centre for Anti-Infectives Research (; W; CAIR) at the University of Dundee, UK, held an international conference with the aim of discussing some key questions around discovering new medicines for infectious diseases and a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4aded55419b192e43a1d93bef190a7b
https://eprints.gla.ac.uk/205951/1/205951.pdf
https://eprints.gla.ac.uk/205951/1/205951.pdf
Autor:
Alex Chao, Boon Heng Lee, Kah Fei Wan, David Beer, Peter Gedeck, Thierry T. Diagana, Jeremy J. Selva, Bin Zou, Ujjini H. Manjunatha, Ghislain M. C. Bonamy
Publikováno v:
ACS Infectious Diseases. 4:635-645
Cryptosporidiosis is a diarrheal disease predominantly caused by Cryptosporidium parvum ( Cp) and Cryptosporidium hominis ( Ch), apicomplexan parasites which infect the intestinal epithelial cells of their human hosts. The only approved drug for cryp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3ddd4502b82cabe3c01150538fcfbb
https://doi.org/10.1021/acsinfecdis.7b00247
https://doi.org/10.1021/acsinfecdis.7b00247