Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ujjal Singha"'
Autor:
Wenxu Zhou, Emilio Ramos, Xunlu Zhu, Paxtyn M. Fisher, Medhanie E. Kidane, Boden H. Vanderloop, Crista D. Thomas, Juqiang Yan, Ujjal Singha, Minu Chaudhuri, Michael T. Nagel, W.David Nes
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 5, Pp 981-994 (2019)
Pathogenic organisms may be sensitive to inhibitors of sterol biosynthesis, which carry antimetabolite properties, through manipulation of the key enzyme, sterol methyltransferase (SMT). Here, we isolated natural suicide substrates of the ergosterol
Externí odkaz:
https://doaj.org/article/09be2b3fa76c4660b95ac736ad3c5f60
Autor:
Medhanie E. Kidane, Boden H. Vanderloop, Wenxu Zhou, Crista D. Thomas, Emilio Ramos, Ujjal Singha, Minu Chaudhuri, W. David Nes
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 12, Pp 2310-2323 (2017)
Ergosterol biosynthesis pathways essential to pathogenic protozoa growth and absent from the human host offer new chokepoint targets. Here, we present characterization and cell-based interference of Acanthamoeba spp sterol 24-/28-methylases (SMTs) th
Externí odkaz:
https://doaj.org/article/c5dd241f6f744dcebd1bd6c255049167
Publikováno v:
Parasitology Research; Apr2008, Vol. 102 Issue 5, p835-844, 10p