Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ujjal D. S. Sekhon"'
Autor:
Ujjal D. S. Sekhon, Aditya Girish, Anirban Sen Gupta, Norman F. Luc, Nathan A. Rohner, Matthew D. Neal
Publikováno v:
Platelets
Platelets are anucleate blood cells produced from megakaryocytes predominantly in the bone marrow and released into blood circulation at a healthy count of 150,000-400,00 per μL and circulation lifespan of 7-9 days. Platelets are the first responder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d5a5bf0c31552810acd3c341279dd2
https://europepmc.org/articles/PMC8795470/
https://europepmc.org/articles/PMC8795470/
Autor:
Anirban Sen Gupta, Stephanie Huang, Michael Sun, Norman F. Luc, DaShawn A. Hickman, Kenji Miyazawa, Yifeng Ma, Ankush Banerjee, Ujjal D. S. Sekhon, Aditya Girish
Publikováno v:
J Thromb Haemost
Background Trauma-associated hemorrhage and coagulopathy remain leading causes of mortality. Such coagulopathy often leads to a hyperfibrinolytic phenotype where hemostatic clots become unstable because of upregulated tissue plasminogen activator (tP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39da5b748386156595a17da1c558fae
https://doi.org/10.1111/jth.14552
https://doi.org/10.1111/jth.14552
Autor:
Ujjal D. S. Sekhon, Anirban Sen Gupta
Publikováno v:
ACS biomaterials scienceengineering. 4(4)
Wound healing is a complex biological process involving distinct phases of hemostasis, immune response, and inflammatory events, regulated cellular proliferation, and matrix remodeling. While immune and inflammatory cellular phenotypes (e.g., neutrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c147e6a8418b879179f18db2ca342d9
https://pubmed.ncbi.nlm.nih.gov/33418655
https://pubmed.ncbi.nlm.nih.gov/33418655
Autor:
Sina Pourang, Michael A. Suster, Pedram Mohseni, Anirban Sen Gupta, Debnath Maji, Ujjal D. S. Sekhon
Publikováno v:
2020 IEEE SENSORS.
This paper reports on the use of a microfluidic dielectric sensor, termed ClotChip, for monitoring the fibrin polymerization effects on whole blood coagulation. The ClotChip sensor readout captures the temporal variation in the normalized real part o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee4f1453df3f0a48826047d98adb8f80
https://doi.org/10.1109/sensors47125.2020.9278794
https://doi.org/10.1109/sensors47125.2020.9278794
Publikováno v:
Transfusion. 60:229-231
Among blood components, platelets (PLTs) present the toughest logistic challenges in transfusion due to limited availability, difficult portability and storage, high contamination risks, and very short shelf life (approx. 5 days). Robust research eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425c741bdda447ca52ba36950e71501c
https://doi.org/10.1111/trf.15543
https://doi.org/10.1111/trf.15543
Autor:
Debnath Maji, Erdem Kucukal, Michael A. Suster, Anirban Sen Gupta, Umut A. Gurkan, Evi X. Stavrou, Ujjal D. S. Sekhon, Pedram Mohseni
Publikováno v:
IEEE Transactions on Biomedical Circuits and Systems. 11:1459-1469
This paper describes the design, fabrication, and testing of a microfluidic sensor for dielectric spectroscopy (DS) of human whole blood during coagulation. The sensor, termed ClotChip, employs a three-dimensional (3D), parallel-plate, capacitive sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc4d5f1e019a57720dcd12827a304c9
https://doi.org/10.1109/tbcas.2017.2739724
https://doi.org/10.1109/tbcas.2017.2739724
Autor:
Anirban Sen Gupta, Debnath Maji, Ujjal D. S. Sekhon, Pedram Mohseni, Sina Pourang, Michael A. Suster
Publikováno v:
2019 IEEE SENSORS.
This paper reports on capturing the morphological changes in red blood cells (RBCs) during platelet-driven blood clot retraction using a microfluidic dielectric sensor, termed ClotChip. The sensor is based on the technique of dielectric spectroscopy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b222f89006b587621ccda5e874ad4fba
https://doi.org/10.1109/sensors43011.2019.8956491
https://doi.org/10.1109/sensors43011.2019.8956491
Autor:
Victor Pan, Ujjal D. S. Sekhon, Anirban Sen Gupta, Preethi N. Siva, Christa L. Modery-Pawlowski
Publikováno v:
RSC Advances. 5:46218-46228
The ‘targeted nanomedicine’ approach has revolutionized cancer therapy by packaging drugs within nanovehicles that can accumulate preferentially within the tumor due to the ‘enhanced permeation and retention’ (EPR) mechanism (passive targetin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e92fa7e1ccd0af0e6a4b09e13fa739f7
https://doi.org/10.1039/c5ra05339k
https://doi.org/10.1039/c5ra05339k
Autor:
Ann H. Kim, Aditya Girish, Andrew Shevitz, Mitchell Dyer, Norman F. Luc, DaShawn A. Hickman, Vikram S. Kashyap, Christa L. Pawlowski, Anirban Sen Gupta, Stephanie Huang, Michael Sun, Ujjal D. S. Sekhon, Edward F. Niedoba, Matthew D. Neal, Joyann Marks, Simi Ganjoo
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Traumatic non-compressible hemorrhage is a leading cause of civilian and military mortality and its treatment requires massive transfusion of blood components, especially platelets. However, in austere civilian and battlefield locations, access to pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fe88cc6fd03976fac9b8d95aa5fc13
https://pubmed.ncbi.nlm.nih.gov/29449604
https://pubmed.ncbi.nlm.nih.gov/29449604
Autor:
A. Sen Gupta, Alvin H. Schmaier, M. de la Fuente, Erdem Kucukal, Marvin T. Nieman, Evi X. Stavrou, Michael A. Suster, Umut A. Gurkan, Debnath Maji, Pedram Mohseni, Ujjal D. S. Sekhon
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 16(10)
Essentials ClotChip is a novel microsensor for comprehensive assessment of ex vivo hemostasis. Clinical samples show high sensitivity to detecting the entire hemostatic process. ClotChip readout exhibits distinct information on coagulation factor and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbeaeaf940bf1231b30bd62ad41bf52
https://pubmed.ncbi.nlm.nih.gov/30007048
https://pubmed.ncbi.nlm.nih.gov/30007048