Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ui Hyun Park"'
Publikováno v:
Applied Biological Chemistry, Vol 67, Iss 1, Pp 1-10 (2024)
Abstract Piperine, an alkaloid compound in black pepper (Piper nigrum), has beneficial bioactivities. Specifically, piperine inhibits adipogenesis in 3T3-L1 cells by suppressing the transcriptional activity of PPARγ. Control of hair oiliness, which
Externí odkaz:
https://doaj.org/article/b1a4f2dcbbe548d58590a4392d03736d
Autor:
Sang Hyup Lee, Ji-Hye Yang, Ui-Hyun Park, Hanbyeul Choi, Yoo Sung Kim, Bo-Eun Yoon, Hye-Jeong Han, Hyun-Taek Kim, Soo-Jong Um, Eun-Joo Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 6, Pp 1232-1246 (2023)
Abstract SIRT1, a member of the mammalian sirtuin family, is a nicotinamide adenosine dinucleotide (NAD)-dependent deacetylase with key roles in aging-related diseases and cellular senescence. However, the mechanism by which SIRT1 protein homeostasis
Externí odkaz:
https://doaj.org/article/616241520e48488abcffd5f96b594298
Autor:
Hye Sook Youn, Tae-Yoon Kim, Ui-Hyun Park, Seung-Tae Moon, So-Jung An, Yong-Kyu Lee, Jin-Taek Hwang, Eun-Joo Kim, Soo-Jong Um
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Although ASXL1 mutations are frequently found in human diseases, including myeloid leukemia, the cell proliferation–associated function of ASXL1 is largely unknown. Here, we explored the molecular mechanism underlying the growth defect fou
Externí odkaz:
https://doaj.org/article/aeedf74d7e724fa6bb3f01a2f6594b3d
Publikováno v:
Electronics; Volume 12; Issue 8; Pages: 1906
The rapid expansion of remote work following the COVID-19 pandemic has necessitated the development of more robust and secure endpoint device security solutions. Companies have begun to adopt the zero trust security concept as an alternative to tradi
Publikováno v:
Nutrients; Volume 15; Issue 7; Pages: 1797
Shikonin, a natural ingredient produced by Lithospermum erythrorhizon, has anti-inflammatory, anti-cancer, and anti-obesity effects. It also inhibits adipocyte differentiation; however, the underlying molecular and epigenetic mechanisms remain unclea
Publikováno v:
Phytotherapy Research. 33:2429-2439
Previously, we reported that piperine, one of the major pungent components in black pepper, attenuates adipogenesis by repressing PPARγ activity in 3T3-L1 preadipocytes. However, the epigenetic mechanisms underlying this activity remain unexplored.
Publikováno v:
Journal of Physiology & Pathology in Korean Medicine. 33:82-88
Autor:
Seungtae Moon, Jin-Taek Hwang, Ui-Hyun Park, Eun-Joo Kim, HyeSook Youn, Soo-Jong Um, So-Jung An, Myengmo Kang
Publikováno v:
Biochemical and Biophysical Research Communications. 508:907-913
Additional sex comb-like1 (Asxl1) is known as a chromatin modulator that plays dual functions in transcriptional regulation depending on the cell type. Recent studies using Asxl1 knockout mice revealed that Asxl1 is important for the proliferation an
Autor:
HyeSook Youn, Joo Yeon Kim, Nackhyoung Kim, So Jung An, Sun Kyoung Im, Ji Hoon Kim, Eun-Joo Kim, Woong Sun, A Reum Kim, Seungtae Moon, Jin Taek Hwang, Soo-Jong Um, Ui Hyun Park
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 11, Pp 1-14 (2018)
Cell Death and Disease, Vol 9, Iss 11, Pp 1-14 (2018)
Although additional sex combs-like 1 (ASXL1) has been extensively described in hematologic malignancies, little is known about the molecular role of ASXL1 in organ development. Here, we show that Asxl1 ablation in mice results in postnatal lethality
Publikováno v:
CELL DEATH & DISEASE(8)
Cell Death and Disease, Vol 8, Iss 12, Pp 1-14 (2017)
Cell Death & Disease
Cell Death and Disease, Vol 8, Iss 12, Pp 1-14 (2017)
Cell Death & Disease
Peroxisome proliferator-activated receptor γ (PPARγ) is the master regulator of adipocyte differentiation and is closely linked to the development of obesity. Despite great progress in elucidating the transcriptional network of PPARγ, epigenetic r