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Autor:
Fabien Filaire, Aurélie Sécula, Pierre Bessière, Marielle Pagès-Homs, Jean-Luc Guérin, Frederic Violleau, Ugo Till
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract High and low pathogenicity avian influenza viruses (HPAIV, LPAIV) are the primary causes of poultry diseases worldwide. HPAIV and LPAIV constitute a major threat to the global poultry industry. Therefore, early detection and well-adapted sur
Externí odkaz:
https://doaj.org/article/d8f91876027d4f3191a9892162690477
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
Multiple myeloma (MM), characterized by abnormal proliferation of clonal plasma cells, is an incurable hematological malignancy. Various immunotherapy strategies have emerged as an efficacious approach for the treatment of MM, including monoclonal an
Externí odkaz:
https://doaj.org/article/dc319dc577a34aa4bf295fb24119c0dc
Autor:
Valentina Trimarco, Raffaele Izzo, Daniela Pacella, Ugo Trama, Maria Virginia Manzi, Angela Lombardi, Roberto Piccinocchi, Paola Gallo, Giovanni Esposito, Gaetano Piccinocchi, Maria Lembo, Carmine Morisco, Francesco Rozza, Gaetano Santulli, Bruno Trimarco
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background While the augmented incidence of diabetes after COVID-19 has been widely confirmed, controversial results are available on the risk of developing hypertension during the COVID-19 pandemic. Methods We designed a longitudinal cohort
Externí odkaz:
https://doaj.org/article/9aab101e69604dedbe0badb68914a360
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
Blinatumomab, a CD19-CD3 bispecific T cell engager (BiTE), has two recombinant single-chain variable fragments that temporarily link CD3+ T cells and CD19+ B cells, leading to the T cell-mediated lysis of neoplastic B cells. Improved minimal residual
Externí odkaz:
https://doaj.org/article/880f4b38f3164cb48f22c1876c312b46
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
In the last ten years, a consistent number of clinical studies have evaluated different gene approaches for the treatment of patients with sickle cell disease (SCD) and transfusion-dependent b-thalassemia (TDT). Initial studies of gene therapy for he
Externí odkaz:
https://doaj.org/article/c45c231579d8442a954580e3710636ef
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
Multiple myeloma (MM) is a disorder of the monoclonal plasma cells and is the second most common hematologic malignancy. MM initiation and progression are dependent upon complex genomic abnormalities. The current pathogenic model of MM includes two t
Externí odkaz:
https://doaj.org/article/d55cce9b860d4128a37eb68ba5c25808
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
The study of monoclonal serum proteins has led to the generation of two major theories: one proposing that individuals who had monoclonal proteins without any symptoms or evidence of end-organ damage have a benign condition; the other one suggesting
Externí odkaz:
https://doaj.org/article/f94bc27a002d489ebcd4f23b80232e3c
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
The treatment outcomes of patients with chronic lymphocytic leukemia (CLL) have considerably improved with the introduction of targeted therapies based on Bruton kinase inhibitors (BTKIs), venetoclax, and anti-CD20 monoclonal antibodies. However, des
Externí odkaz:
https://doaj.org/article/ed6dee0cb37f4a9db01ec678a57b1ec8
Autor:
Carmine Siniscalchi, Alessandro Perrella, Ugo Trama, Francesca Futura Bernardi, Egidio Imbalzano, Giuseppe Camporese, Vincenzo Russo, Olga Scudiero, Tiziana Meschi, Pierpaolo Di Micco
Publikováno v:
Toxins, Vol 16, Iss 8, p 368 (2024)
The association between sepsis and thrombotic complications is still not well known. Different mechanisms have been shown to be involved in the sepsis-induced prothrombotic state, but clinical scenarios may differ. In this review, we have summarized
Externí odkaz:
https://doaj.org/article/f02caf7ca35a494bb8d7fc13693539dc