Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Ugo Moens"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Modified vaccinia virus Ankara (MVA) has been widely tested in clinical trials as recombinant vector vaccine against infectious diseases and cancers in humans and animals. However, one biosafety concern about the use of MVA vectored vaccine is the po
Externí odkaz:
https://doaj.org/article/b0a9b97800474e5c9ad8144adb66b43d
Autor:
Emmanuel Alakunle, Daniel Kolawole, Diana Diaz-Cánova, Faith Alele, Oyelola Adegboye, Ugo Moens, Malachy Ifeanyi Okeke
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Monkeypox virus (MPXV) is the etiological agent of monkeypox (mpox), a zoonotic disease. MPXV is endemic in the forested regions of West and Central Africa, but the virus has recently spread globally, causing outbreaks in multiple non-endemic countri
Externí odkaz:
https://doaj.org/article/d76e55cee8fc410092dc488a7732838d
Autor:
Sara Passerini, Giulia Babini, Elisabetta Merenda, Raffaella Carletti, Daniela Scribano, Luigi Rosa, Antonietta Lucia Conte, Ugo Moens, Livia Ottolenghi, Umberto Romeo, Maria Pia Conte, Cira Rosaria Tiziana Di Gioia, Valeria Pietropaolo
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 709 (2024)
Despite recent advances in prevention, detection and treatment, oral squamous cell carcinoma (OSCC) remains a global health concern, strongly associated with environmental and lifestyle risk factors and infection with oncogenic viruses. Merkel Cell P
Externí odkaz:
https://doaj.org/article/02d44f3faa9f43309cfb34ce01fda1e2
Publikováno v:
Viruses, Vol 15, Iss 11, p 2235 (2023)
Protein phosphorylation and dephosphorylation are the most common post-translational modifications mediated by protein kinases and protein phosphatases, respectively. These reversible processes can modulate the function of the target protein, such as
Externí odkaz:
https://doaj.org/article/c6472066a2044c94bd40623c60103c69
Autor:
Sara Passerini, Carla Prezioso, Giulia Babini, Amedeo Ferlosio, Terenzio Cosio, Elena Campione, Ugo Moens, Marco Ciotti, Valeria Pietropaolo
Publikováno v:
Pathogens, Vol 12, Iss 7, p 894 (2023)
Merkel cell polyomavirus (MCPyV) is the etiological agent of the majority of Merkel cell carcinoma (MCC): a rare skin tumor. To improve our understanding of the role of MCPyV in MCCs, the detection and analysis of MCPyV DNA and transcripts were perfo
Externí odkaz:
https://doaj.org/article/a9b0f1af426249c28a4a97439ff06cfe
Publikováno v:
Virology Journal, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Background Approximately 15% of human cancers are attributed to viruses. Numerous studies have shown that high-risk human polyomaviruses (HR-HPV) and Merkel cell polyomavirus (MCPyV) are two human tumor viruses associated with anogenetal and
Externí odkaz:
https://doaj.org/article/64ea1fa14405470c89453dfd82562397
Publikováno v:
Virology Journal, Vol 18, Iss 1, Pp 1-7 (2021)
Abstract Background Human polyomavirus 6 (HPyV6) and HPyV7 are two of the novel polyomaviruses that were originally detected in non-diseased skin. Serological studies have shown that these viruses are ubiquitous in the healthy adult population with s
Externí odkaz:
https://doaj.org/article/438804863cfc41b082408785b47d2b46
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
As their name indicates, polyomaviruses (PyVs) can induce tumors. Mouse PyV, hamster PyV and raccoon PyV have been shown to cause tumors in their natural host. During the last 30 years, 15 PyVs have been isolated from humans. From these, Merkel cell
Externí odkaz:
https://doaj.org/article/2c0aab52b47042d596939c476aee61c7
Publikováno v:
Virology Journal, Vol 17, Iss 1, Pp 1-10 (2020)
Abstract Background Merkel cell polyomavirus (MCPyV) is a human polyomavirus that establishes a life-long harmless infection in most individuals, with dermal fibroblasts believed to be the natural host cell. However, this virus is the major cause of
Externí odkaz:
https://doaj.org/article/fd904f0d52cf4922b0e91a6f2f2e40ac
Autor:
Mar Falquet, Carla Prezioso, Maria Ludvigsen, Jack-Ansgar Bruun, Sara Passerini, Baldur Sveinbjørnsson, Valeria Pietropaolo, Ugo Moens
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 895 (2023)
Merkel cell polyomavirus (MCPyV) is the major cause of Merkel cell carcinoma (MCC), an aggressive skin cancer. MCPyV large T-antigen (LTag) and small T-antigen (sTag) are the main oncoproteins involved in MCPyV-induced MCC. A hallmark of MCPyV-positi
Externí odkaz:
https://doaj.org/article/0276d01ad30d4c0ebfc6b239b2612c2c