Zobrazeno 1 - 10
of 595
pro vyhledávání: '"Ugo, De Giorgi"'
Autor:
Simone Scagnoli, Simona Pisegna, Angela Toss, Roberta Caputo, Michelino De Laurentiis, Michela Palleschi, Ugo de Giorgi, Enrico Cortesi, Agnese Fabbri, Alessandra Fabi, Ida Paris, Armando Orlandi, Giuseppe Curigliano, Carmen Criscitiello, Ornella Garrone, Gianluca Tomasello, Giuliana D’Auria, Patrizia Vici, Enrico Ricevuto, Federica Domati, Claudia Piombino, Sara Parola, Roberta Scafetta, Alessio Cirillo, Beatrice Taurelli Salimbeni, Francesca Sofia Di Lisa, Lidia Strigari, Robert Preissner, Maurizio Simmaco, Daniele Santini, Paolo Marchetti, Andrea Botticelli
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Abemaciclib demonstrated clinical benefit in women affected by HR+/HER2− advanced breast cancer (aBC). Drug-drug interactions (DDIs) can lead to reduced treatment efficacy or increased toxicity. This retro-prospective study aimed to evalua
Externí odkaz:
https://doaj.org/article/9f47555ab4e54af1bfb2ac3aefc63ec9
Autor:
Sara Elena Rebuzzi, Giuseppe Fornarini, Alessio Signori, Sebastiano Buti, Giuseppe Procopio, Ugo De Giorgi, Sandro Pignata, Emanuele Naglieri, Marco Maruzzo, Giuseppe Luigi Banna, Pasquale Rescigno, Carlo Messina, Alvise Mattana, Umberto Basso, Davide Bimbatti
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-5 (2024)
Abstract Background Nowadays, different therapeutic options are available for the first-line treatment of metastatic renal cell carcinoma (mRCC). Immuno-combinations are the standard first-line therapy in all mRCC patients regardless of the Internati
Externí odkaz:
https://doaj.org/article/07fb9d1891ed48f8877a4dc092e2bedf
Autor:
Fabio Canino, Monica Barbolini, Ugo De Giorgi, Tommaso Fontana, Valeria Gaspari, Caterina Gianni, Lorenzo Gianni, Antonio Maestri, Santino Minichillo, Luca Moscetti, Antonella Mura, Stefania Vittoria Luisa Nicoletti, Claudia Omarini, Rachele Pagani, Samanta Sarti, Angela Toss, Claudio Zamagni, Riccardo Cuoghi Costantini, Federica Caggia, Giuseppina Antonelli, Federica Baglio, Lorenzo Belluzzi, Giulio Martinelli, Salvatore Natalizio, Ornella Ponzoni, Massimo Dominici, Federico Piacentini
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background The addition of pertuzumab (P) to trastuzumab (H) and standard chemotherapy (CT) as neoadjuvant treatment (NaT) for patients with HER2 + breast cancer (BC), has shown to increase the pathological complete response (pCR) rate, with
Externí odkaz:
https://doaj.org/article/1ac6fc48a61047d696aefc89f35bee02
Autor:
Chiara Casadei, Emanuela Scarpi, Vincenza Conteduca, Giorgia Gurioli, Maria Concetta Cursano, Nicole Brighi, Cristian Lolli, Giuseppe Schepisi, Umberto Basso, Giuseppe Fornarini, Sara Bleve, Alberto Farolfi, Amelia Altavilla, Salvatore Luca Burgio, Emilio Francesco Giunta, Caterina Gianni, Alessia Filograna, Paola Ulivi, David Olmos, Elena Castro, Ugo De Giorgi
Publikováno v:
European Urology Open Science, Vol 61, Iss , Pp 44-51 (2024)
Background: The prevalence of pathogenic germline mutations in DNA damage repair (gDDR) genes in the Italian population is unknown. Objective: In this prospective multicenter cohort study, we evaluated the prevalence of gDDR alterations in the Italia
Externí odkaz:
https://doaj.org/article/da61ee9b940b4381ac3aa92030e5b551
Autor:
Martina Catalano, Sara Elena Rebuzzi, Marco Maruzzo, Ugo De Giorgi, Sebastiano Buti, Luca Galli, Giuseppe Fornarini, Paolo Andrea Zucali, Melanie Claps, Silvia Chiellino, Ilaria Zampiva, Stefania Pipitone, Riccardo Ricotta, Mariella Sorarù, Veronica Mollica, Marianna Tudini, Lucia Fratino, Veronica Prati, Orazio Caffo, Francesco Atzori, Franco Morelli, Giuseppe Prati, Franco Nolè, Francesca Vignani, Alessia Cavo, Marilena Di Napoli, Andrea Malgeri, Emanuele Naglieri, Alessio Signori, Giuseppe Luigi Banna, Pasquale Rescigno, Linda Cerbone, Lorenzo Antonuzzo, Giandomenico Roviello
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundImmune-checkpoint inhibitors (ICIs) have significantly improved metastatic renal cell carcinoma (mRCC) prognosis, although their efficacy in patients with bone metastases (BMs) remains poorly understood. We investigated the prognostic role
Externí odkaz:
https://doaj.org/article/e1a5d05c7cd04f7d95a2a3e615d48926
Autor:
Lucia Fratino, Jerry Polesel, Emilio Francesco Giunta, Marco Maruzzo, Sebastiano Buti, Mona Ali Hassan, Umberto Basso, Sara Elena Rebuzzi, Ugo De Giorgi, Marika Cinausero, Helga Lipari, Teresa Gamba, Davide Bimbatti, Arianna Dri, Paola Ermacora, Francesca Vignani, Giuseppe Fornarini, Pasquale Rescigno, Giuseppe Luigi Banna
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Instrumental activities of daily living (IADL) are significant health indicators closely related to executive functions and able to detect mild cognitive impairment. A decline in IADL usually precedes ADL limitation, including taking medicat
Externí odkaz:
https://doaj.org/article/6a0ab27419da4917ac402a86c95934eb
Autor:
Enrique Grande, Aristotelis Bamias, Matthew D. Galsky, Eiji Kikuchi, Ian D. Davis, José Ángel Arranz, Arash Rezazadeh Kalebasty, Xavier Garcia del Muro, Se Hoon Park, Ugo De Giorgi, Boris Alekseev, Marina Mencinger, Kouji Izumi, Javier Puente, Jian-Ri Li, Sandrine Bernhard, Alan Nicholas, Julie Telliez, Maria De Santis
Publikováno v:
European Urology Open Science, Vol 58, Iss , Pp 28-36 (2023)
Standard-of-care first-line treatment for metastatic urothelial carcinoma (mUC) is platinum-based chemotherapy (CTx). Maintenance immunotherapy is a treatment option for patients without progressive disease (PD) after induction CTx. IMvigor130 was a
Externí odkaz:
https://doaj.org/article/23174f8611b2473d8705753cdcab834f
Autor:
Alessandra Virga, Caterina Gianni, Michela Palleschi, Davide Angeli, Filippo Merloni, Roberta Maltoni, Paola Ulivi, Giovanni Martinelli, Ugo De Giorgi, Sara Bravaccini
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2183 (2024)
Background: Patients with hormone receptor-positive (HR+)/HER2- metastatic breast cancer (mBC) generally receive hormonal therapy (HT) combined with CDK4/6 inhibitors (CDK4/6i). Despite this treatment, resistance mechanisms to CDK4/6i emerge and the
Externí odkaz:
https://doaj.org/article/b4f6e5029c6b49319727b60fcd9c8bfa
Autor:
Alberto Farolfi, Nicola Gentili, Sara Testoni, Francesca Rusconi, Ilaria Massa, Valentina Danesi, Amelia Altavilla, Maria C. Cursano, Giorgia Gurioli, Salvatore L. Burgio, Gema Hernandez Ibarburu, Ugo De Giorgi
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109680- (2024)
Summary: Endometriosis is a benign condition characterized by the presence of ectopic endometrial tissue. Our study investigated the effect of endometriosis on the risk of endometrial cancer (EC) and the prognosis of endometriosis-associated EC. In o
Externí odkaz:
https://doaj.org/article/85b6f937077f4451ae501a21d4fd140b
Autor:
Mario Campone, François-Clément Bidard, Patrick Neven, Lei Wang, Bin Ling, Yvonne Dong, Gautier Paux, Christina Herold, Ugo De Giorgi
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Window-of-opportunity (WOO) studies provide insights into the clinical activity of new drugs in breast cancer. Methods AMEERA-4 (NCT04191382) was a WOO study undertaken to compare the pharmacodynamic effects of amcenestrant, a sel
Externí odkaz:
https://doaj.org/article/24d87931212c4cbdb6a5a1093b09d570