Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry.

Autor: Bustos BI; Institute of Biomedical Sciences, Faculty of Medicine and Faculty of Life Sciences, Universidad Andrés Bello, Santiago, Chile., Pérez-Palma E; Institute of Biomedical Sciences, Faculty of Medicine and Faculty of Life Sciences, Universidad Andrés Bello, Santiago, Chile., Buch S; Medical Department I, University Hospital Dresden, TU Dresden, Dresden, Germany., Azócar L; Departmento de Gastroenterología, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Riveras E; Departmento de Gastroenterología, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Ugarte GD; Institute of Biomedical Sciences, Faculty of Medicine and Faculty of Life Sciences, Universidad Andrés Bello, Santiago, Chile., Toliat M; Cologne Center for Genomics, University of Cologne, Cologne, Germany., Nürnberg P; Cologne Center for Genomics, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany., Lieb W; Institute of Epidemiology and Biobank PopGen, Christian-Albrechts-University of Kiel, Kiel, Germany., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany., Hinz S; Department of Visceral and Thoracic Surgery, University Hospital Schleswig Holstein, Kiel, Germany., Burmeister G; Department of Visceral and Thoracic Surgery, University Hospital Schleswig Holstein, Kiel, Germany., von Schönfels W; Department of Visceral and Thoracic Surgery, University Hospital Schleswig Holstein, Kiel, Germany., Schafmayer C; Department of Visceral and Thoracic Surgery, University Hospital Schleswig Holstein, Kiel, Germany., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Lerch MM; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Santos JL; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Puschel K; Department of Familiar Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Bambs C; Department of Public Health, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Roa JC; Departamento de Anatomía Patológica, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile., Gutiérrez RA; Department of Molecular Genetics and Microbiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.; FONDAP Center for Genome Regulation (CGR), Santiago, Chile., Hampe J; Medical Department I, University Hospital Dresden, TU Dresden, Dresden, Germany., De Ferrari GV; Institute of Biomedical Sciences, Faculty of Medicine and Faculty of Life Sciences, Universidad Andrés Bello, Santiago, Chile. gdeferrari@unab.cl.; FONDAP Center for Genome Regulation (CGR), Santiago, Chile. gdeferrari@unab.cl., Miquel JF; Departmento de Gastroenterología, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile. jfmiquel@med.puc.cl.; FONDAP Center for Genome Regulation (CGR), Santiago, Chile. jfmiquel@med.puc.cl.

Publikováno v: Scientific reports [Sci Rep] 2019 Jan 28; Vol. 9 (1), pp. 772. Date of Electronic Publication: 2019 Jan 28.

Alternative RUNX1 Promoter Regulation by Wnt/β-Catenin Signaling in Leukemia Cells and Human Hematopoietic Progenitors.

Autor: Medina MA; Faculty of Biological Sciences and Faculty of Medicine, Center for Biomedical Research, Universidad Andres Bello, Santiago, Chile., Ugarte GD; Faculty of Biological Sciences and Faculty of Medicine, Center for Biomedical Research, Universidad Andres Bello, Santiago, Chile., Vargas MF; Faculty of Biological Sciences and Faculty of Medicine, Center for Biomedical Research, Universidad Andres Bello, Santiago, Chile., Avila ME; Faculty of Biological Sciences and Faculty of Medicine, Center for Biomedical Research, Universidad Andres Bello, Santiago, Chile., Necuñir D; Faculty of Biological Sciences and Faculty of Medicine, Center for Biomedical Research, Universidad Andres Bello, Santiago, Chile., Elorza AA; Faculty of Biological Sciences and Faculty of Medicine, Center for Biomedical Research, Universidad Andres Bello, Santiago, Chile.; Millennium Institute on Immunology and Immunotherapy, Santiago, Chile., Gutiérrez SE; Department of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Universidad de Concepción, Concepción, Chile., De Ferrari GV; Faculty of Biological Sciences and Faculty of Medicine, Center for Biomedical Research, Universidad Andres Bello, Santiago, Chile.

Publikováno v: Journal of cellular physiology [J Cell Physiol] 2016 Jul; Vol. 231 (7), pp. 1460-7. Date of Electronic Publication: 2016 Feb 11.

Wnt signaling induces transcription, spatial proximity, and translocation of fusion gene partners in human hematopoietic cells.

Autor: Ugarte GD; Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile; Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias (FONDAP) Center for Genome Regulation, Santiago, Chile;, Vargas MF; Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile; Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias (FONDAP) Center for Genome Regulation, Santiago, Chile;, Medina MA; Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile;, León P; Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile; Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias (FONDAP) Center for Genome Regulation, Santiago, Chile;, Necuñir D; Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile;, Elorza AA; Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile; Millennium Institute on Immunology and Immunotherapy, Santiago, Chile;, Gutiérrez SE; Department of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Universidad de Concepción, Concepción, Chile;, Moon RT; Howard Hughes Medical Institute, Department of Pharmacology and Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, WA; and., Loyola A; Fundación Ciencia and Vida, Santiago, Chile., De Ferrari GV; Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile; Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias (FONDAP) Center for Genome Regulation, Santiago, Chile;

Publikováno v: Blood [Blood] 2015 Oct 08; Vol. 126 (15), pp. 1785-9. Date of Electronic Publication: 2015 Sep 02.

A novel functional low-density lipoprotein receptor-related protein 6 gene alternative splice variant is associated with Alzheimer's disease.

Autor: Alarcón MA; Center for Biomedical Research and FONDAP Center for Genome Regulation, Universidad Andres Bello, Santiago, Chile., Medina MA, Hu Q, Avila ME, Bustos BI, Pérez-Palma E, Peralta A, Salazar P, Ugarte GD, Reyes AE, Martin GM, Opazo C, Moon RT, De Ferrari GV

Publikováno v: Neurobiology of aging [Neurobiol Aging] 2013 Jun; Vol. 34 (6), pp. 1709.e9-18. Date of Electronic Publication: 2012 Dec 06.

Runx1 and C/EBPβ transcription factors directly up-regulate P2X3 gene transcription.

Autor: Ugarte GD; Faculty of Biological Sciences, Department of Biochemistry and Molecular Biology, Universidad de Concepcion, Santiago, Chile., Opazo T, Leisewitz F, van Zundert B, Montecino M

Publikováno v: Journal of cellular physiology [J Cell Physiol] 2012 Apr; Vol. 227 (4), pp. 1645-52.