Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ufuk Borucu"'
Autor:
Gaia Pasqualetto, Andrew Mack, Emily Lewis, Ryan Cooper, Alistair Holland, Ufuk Borucu, Judith Mantell, Tom Davies, Miriam Weckener, Dan Clare, Tom Green, Pete Kille, Alex Muhlhozl, Mark T. Young
Publikováno v:
PLoS ONE, Vol 18, Iss 6 (2023)
Hemocyanins are multimeric oxygen transport proteins present in the blood of arthropods and molluscs, containing up to 8 oxygen-binding functional units per monomer. In molluscs, hemocyanins are assembled in decamer ‘building blocks’ formed of 5
Externí odkaz:
https://doaj.org/article/b7aac8c64276468c8980c9beeaa3cde2
Autor:
Kapil Gupta, Christine Toelzer, Maia Kavanagh Williamson, Deborah K. Shoemark, A. Sofia F. Oliveira, David A. Matthews, Abdulaziz Almuqrin, Oskar Staufer, Sathish K. N. Yadav, Ufuk Borucu, Frederic Garzoni, Daniel Fitzgerald, Joachim Spatz, Adrian J. Mulholland, Andrew D. Davidson, Christiane Schaffitzel, Imre Berger
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
BriSΔ, a SARS-CoV-2 variant from clinical isolate hCoV/England/02/2020, comprises a deletion in a spike cleavage site. The structure and molecular dynamics of this spike provides mechanistic insights into how the deletion modulates virus infectivity
Externí odkaz:
https://doaj.org/article/aca02d9ce50d4ddb8d2a53b3b352d716
Publikováno v:
Nature Materials.
Autor:
Junlai Yu, Libei Huang, Qingxuan Tang, Shang-Bo Yu, Qiao-Yan Qi, Jiangshan Zhang, Danying Ma, Yifei Lei, Jianjun Su, Yun Song, Jean-Charles Eloi, Robert L. Harniman, Ufuk Borucu, Long Zhang, Minghui Zhu, Feng Tian, Lili Du, David Lee Phillips, Ian Manners, Ruquan Ye, Jia Tian
Publikováno v:
Nature Catalysis.
Autor:
Michael D. Healy, Kerrie E. McNally, Rebeka Butkovic, Molly Chilton, Kohji Kato, Joanna Sacharz, Calum McConville, Edmund R.R. Moody, Shrestha Shaw, Vicente J. Planelles-Herrero, Sathish K.N. Yadav, Jennifer Ross, Ufuk Borucu, Catherine S. Palmer, Kai-En Chen, Tristan I. Croll, Ryan J. Hall, Nikeisha J. Caruana, Rajesh Ghai, Thi H.D. Nguyen, Kate J. Heesom, Shinji Saitoh, Imre Berger, Christiane Schaffitzel, Tom A. Williams, David A. Stroud, Emmanuel Derivery, Brett M. Collins, Peter J. Cullen
SUMMARYThe Commander complex is required for endosomal recycling of diverse transmembrane cargos and is mutated in Ritscher-Schinzel syndrome. It comprises two subassemblies; Retriever composed of VPS35L, VPS26C and VPS29, and the CCC complex which c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d210a5342199c943249b9d1af8c0d6
https://doi.org/10.2139/ssrn.4330804
https://doi.org/10.2139/ssrn.4330804
Autor:
Christine Toelzer, Kapil Gupta, Sathish K. N. Yadav, Lorna Hodgson, Maia Kavanagh Williamson, Dora Buzas, Ufuk Borucu, Kyle Powers, Richard Stenner, Kate Vasileiou, Frederic Garzoni, Daniel Fitzgerald, Christine Payré, Gunjan Gautam, Gérard Lambeau, Andrew D. Davidson, Paul Verkade, Martin Frank, Imre Berger, Christiane Schaffitzel
Publikováno v:
Toelzer, C, Gupta, K, Yadav Kadapalakere, S, Hodgson, L R, Kavanagh Williamson, M, Buzas, D, Borucu, U, Powers, K T, Stenner, R A, Vasileiou, K, Garzoni, F, Fitzgerald, D J, Payré, C, Gautam, G, Lambeau, G, Davidson, A D, Verkade, P, Martin, F, Berger, I & Berger-Schaffitzel, C H 2022, ' The Free Fatty Acid-Binding Pocket is a Conserved Hallmark in Pathogenic β-Coronavirus Spike Proteins from SARS-CoV to Omicron ', Science Advances, vol. 8, no. 47, eadc9179 . https://doi.org/10.1101/2022.04.22.489083, https://doi.org/10.1126/sciadv.adc9179
As COVID-19 persists, severe acquired respiratory syndrome coronavirus-2 (SARS-CoV-2) Variants of Concern (VOCs) emerge, accumulating spike (S) glycoprotein mutations. S receptor-binding domain (RBD) comprises a free fatty acid (FFA)-binding pocket.
Autor:
Michael D. Healy, Kerrie E. McNally, Rebeka Butkovič, Molly Chilton, Kohji Kato, Joanna Sacharz, Calum McConville, Edmund R.R. Moody, Shrestha Shaw, Vicente J. Planelles-Herrero, Sathish K.N. Yadav, Jennifer Ross, Ufuk Borucu, Catherine S. Palmer, Kai-En Chen, Tristan I. Croll, Ryan J. Hall, Nikeisha J. Caruana, Rajesh Ghai, Thi H.D. Nguyen, Kate J. Heesom, Shinji Saitoh, Imre Berger, Christiane Schaffitzel, Tom A. Williams, David A. Stroud, Emmanuel Derivery, Brett M. Collins, Peter J. Cullen
Publikováno v:
Cell. 186:2219-2237.e29
Seeded growth of crystallizable block copolymers and π-stacking molecular amphiphiles in solution using the living crystallization-driven self-assembly (CDSA) method is attracting growing interest as a route to uniform 1D and 2D core–shell micella
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d9c22d639451113c9fba55aec313616
https://doi.org/10.21203/rs.3.rs-1671697/v1
https://doi.org/10.21203/rs.3.rs-1671697/v1
Autor:
Matthias W. Hentze, K.N. Sathish Yadav, Gabriele Neu-Yilik, Beate Amthor, Joshua C. Bufton, Jonas Philipp Becker, Dakang Shen, Kyle T. Powers, Andreas E. Kulozik, Flint Stevenson-Jones, Ufuk Borucu, Christiane Schaffitzel, Daria Lavysh
Publikováno v:
Nucleic Acids Research
Powers, K T, Stevenson-Jones, F R, Yadav Kadapalakere, S, Bufton, J C, Borucu, U, Shen, D & Berger-Schaffitzel, C H 2021, ' Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA ', Nucleic Acids Research, vol. 49, no. 13, pp. 7665-7679 . https://doi.org/10.1093/nar/gkab532
Powers, K T, Stevenson-Jones, F R, Yadav Kadapalakere, S, Bufton, J C, Borucu, U, Shen, D & Berger-Schaffitzel, C H 2021, ' Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA ', Nucleic Acids Research, vol. 49, no. 13, pp. 7665-7679 . https://doi.org/10.1093/nar/gkab532
Deciphering translation is of paramount importance for the understanding of many diseases, and antibiotics played a pivotal role in this endeavour. Blasticidin S (BlaS) targets translation by binding to the peptidyl transferase center of the large ri
Autor:
Johannes F. Weijman, Sathish K. N. Yadav, Katherine J. Surridge, Jessica A. Cross, Ufuk Borucu, Judith Mantell, Derek N. Woolfson, Christiane Schaffitzel, Mark P. Dodding
Despite continuing progress in kinesin enzyme mechanochemistry and emerging understanding of the cargo recognition machinery, it is not known how these functions are coupled and controlled by the alpha-helical coiled coils encoded by a large componen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8659de7efca7974a4f2d3bb4295b8395
https://doi.org/10.1101/2022.04.28.489841
https://doi.org/10.1101/2022.04.28.489841