Growing a circular economy with fungal biotechnology: a white paper

Autor: Vera Meyer, Evelina Y. Basenko, J. Philipp Benz, Gerhard H. Braus, Mark X. Caddick, Michael Csukai, Ronald P. de Vries, Drew Endy, Jens C. Frisvad, Nina Gunde-Cimerman, Thomas Haarmann, Yitzhak Hadar, Kim Hansen, Robert I. Johnson, Nancy P. Keller, Nada Kraševec, Uffe H. Mortensen, Rolando Perez, Arthur F. J. Ram, Eric Record, Phil Ross, Volha Shapaval, Charlotte Steiniger, Hans van den Brink, Jolanda van Munster, Oded Yarden, Han A. B. Wösten

Publikováno v: Fungal Biology and Biotechnology, Vol 7, Iss 1, Pp 1-23 (2020)

Abstract Fungi have the ability to transform organic materials into a rich and diverse set of useful products and provide distinct opportunities for tackling the urgent challenges before all humans. Fungal biotechnology can advance the transition fro

Externí odkaz: https://doaj.org/article/79587d4d7bd94545823f6e23e6f66477

The Aspergillus fumigatus Phosphoproteome Reveals Roles of High-Osmolarity Glycerol Mitogen-Activated Protein Kinases in Promoting Cell Wall Damage and Caspofungin Tolerance

Autor: Eliciane Cevolani Mattos, Lilian Pereira Silva, Clara Valero, Patrícia Alves de Castro, Thaila Fernanda dos Reis, Liliane F. C. Ribeiro, Mark R. Marten, Rafael Silva-Rocha, Cauã Westmann, Carlos Henrique Tomich de Paula da Silva, Carlton Anthony Taft, Narjes Al-Furaiji, Michael Bromley, Uffe H. Mortensen, J. Philipp Benz, Neil Andrew Brown, Gustavo H. Goldman

Publikováno v: mBio, Vol 11, Iss 1 (2020)

ABSTRACT The filamentous fungus Aspergillus fumigatus can cause a distinct set of clinical disorders in humans. Invasive aspergillosis (IA) is the most common life-threatening fungal disease of immunocompromised humans. The mitogen-activated protein

Externí odkaz: https://doaj.org/article/e4362aac315c465db4926930d9ce17bc

Benchmarking two commonly used Saccharomyces cerevisiae strains for heterologous vanillin-β-glucoside production

Autor: Tomas Strucko, Olivera Magdenoska, Uffe H Mortensen

Publikováno v: Metabolic Engineering Communications, Vol 2, Iss , Pp 99-108 (2015)

The yeast Saccharomyces cerevisiae is a widely used eukaryotic model organism and a key cell factory for production of biofuels and wide range of chemicals. From the broad palette of available yeast strains, the most popular are those derived from la

Externí odkaz: https://doaj.org/article/0df85029f5c44243906561167039398e

Biosynthesis of Calipyridone A Represents a Fungal 2-Pyridone Formation without Ring Expansion in Aspergillus californicus

Autor: Yaojie Guo, Fabiano J. Contesini, Xinhui Wang, Simone Ghidinelli, Ditte S. Tornby, Thomas E. Andersen, Uffe H. Mortensen, Thomas O. Larsen

Publikováno v: Guo, Y, Contesini, F J, Wang, X, Ghidinelli, S, Tornby, D S, Andersen, T E, Mortensen, U H & Larsen, T O 2022, ' Biosynthesis of Calipyridone A Represents a Fungal 2-Pyridone Formation without Ring Expansion in Aspergillus californicus ', Organic Letters, vol. 24, no. 3, pp. 804-808 . https://doi.org/10.1021/acs.orglett.1c03792

A chemical investigation of the filamentous fungus Aspergillus californicus led to the isolation of a polyketide–nonribosomal peptide hybrid, calipyridone A (1). A putative biosynthetic gene cluster cpd for production of 1 was next identified by ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e564bf4d5113263e1bcee22cb551e2a0
https://portal.findresearcher.sdu.dk/da/publications/8da76b3e-c780-437e-98b9-1258f7178ca7

Genetics of Polyketide Metabolism in Aspergillus nidulans

Autor: Marie L. Klejnstrup, Rasmus J. N. Frandsen, Dorte K. Holm, Morten T. Nielsen, Uffe H. Mortensen, Thomas O. Larsen, Jakob B. Nielsen

Publikováno v: Metabolites, Vol 2, Iss 1, Pp 100-133 (2012)

Secondary metabolites are small molecules that show large structural diversity and a broad range of bioactivities. Some metabolites are attractive as drugs or pigments while others act as harmful mycotoxins. Filamentous fungi have the capacity to pro

Externí odkaz: https://doaj.org/article/2c746d6b1e234c859cbfd66b021bb955