Propofol and Fentanyl Pharmacokinetics and Pharmacodynamics in Extracorporeal Membrane Oxygenation.

Autor: Morales Castro D; University of Toronto, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada; Diana.moralescastro@uhn.ca., Balzani E; University of Toronto, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada., Abdul-Aziz MH; The University of Queensland Centre for Clinical Research, Herston, Queensland, Australia., Hernandez-Mitre MP; The University of Queensland Centre for Clinical Research, Herston, Queensland, Australia., Wong I; University of Toronto, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada., Turgeon J; University of Toronto, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada., Tisminetzky M; University of Toronto, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada., Jurado-Camacho F; University of Toronto Faculty of Medicine, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada., Morris I; University of Toronto, Toronto, Ontario, Canada., Dresser L; University of Toronto Leslie Dan Faculty of Pharmacy, Toronto, Ontario, Canada., Granton J; University of Toronto, Medicine, Toronto, Ontario, Canada., Uetrecht J; University of Toronto Leslie Dan Faculty of Pharmacy, Toronto, Ontario, Canada., Pang KS; University of Toronto Leslie Dan Faculty of Pharmacy, Toronto, Ontario, Canada., Chen E; University of Toronto Leslie Dan Faculty of Pharmacy, Toronto, Ontario, Canada., Shekar K; University of Queensland, Medicine, Brisbane, Queensland, Australia., Fan E; University of Toronto, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada.

Publikováno v: Annals of the American Thoracic Society [Ann Am Thorac Soc] 2024 Oct 09. Date of Electronic Publication: 2024 Oct 09.

The role of corticosterone in nevirapine-induced idiosyncratic drug-induced liver injury.

Autor: Jee A; Department of Pharmacology & Toxicology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 3M2, Canada., Sernoskie SC; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada., Uetrecht J; Department of Pharmacology & Toxicology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 3M2, Canada.; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2024 Jun 26; Vol. 200 (1), pp. 146-164.

Involvement of Extracellular Vesicles in the Proinflammatory Response to Clozapine: Implications for Clozapine-Induced Agranulocytosis.

Autor: Sernoskie SC; Departments of Pharmaceutical Sciences, Faculty of Pharmacy (S.C.S., J.U.) and Pharmacology and Toxicology, Temerty Faculty of Medicine (A.J., J.U.), University of Toronto, Toronto, Ontario; and Institute for Research in Immunology and Cancer (É.B., P.T.) and Department of Chemistry (P.T.), University of Montreal, Montreal, Quebec., Bonneil É; Departments of Pharmaceutical Sciences, Faculty of Pharmacy (S.C.S., J.U.) and Pharmacology and Toxicology, Temerty Faculty of Medicine (A.J., J.U.), University of Toronto, Toronto, Ontario; and Institute for Research in Immunology and Cancer (É.B., P.T.) and Department of Chemistry (P.T.), University of Montreal, Montreal, Quebec., Thibault P; Departments of Pharmaceutical Sciences, Faculty of Pharmacy (S.C.S., J.U.) and Pharmacology and Toxicology, Temerty Faculty of Medicine (A.J., J.U.), University of Toronto, Toronto, Ontario; and Institute for Research in Immunology and Cancer (É.B., P.T.) and Department of Chemistry (P.T.), University of Montreal, Montreal, Quebec., Jee A; Departments of Pharmaceutical Sciences, Faculty of Pharmacy (S.C.S., J.U.) and Pharmacology and Toxicology, Temerty Faculty of Medicine (A.J., J.U.), University of Toronto, Toronto, Ontario; and Institute for Research in Immunology and Cancer (É.B., P.T.) and Department of Chemistry (P.T.), University of Montreal, Montreal, Quebec., Uetrecht J; Departments of Pharmaceutical Sciences, Faculty of Pharmacy (S.C.S., J.U.) and Pharmacology and Toxicology, Temerty Faculty of Medicine (A.J., J.U.), University of Toronto, Toronto, Ontario; and Institute for Research in Immunology and Cancer (É.B., P.T.) and Department of Chemistry (P.T.), University of Montreal, Montreal, Quebec jack.uetrecht@utoronto.ca.

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2024 Feb 15; Vol. 388 (3), pp. 827-845. Date of Electronic Publication: 2024 Feb 15.

Potential Involvement of Sulfotransferase in the Mechanism of Lamotrigine-induced Skin Rash.

Autor: Cao Y; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada M5S 3M2., Bairam A; Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, University of Toledo Health Science Campus, Toledo, Ohio 43614, United States., Liu MC; Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, University of Toledo Health Science Campus, Toledo, Ohio 43614, United States., Uetrecht J; Leslie Dan Faculty of Pharmacy and Faculty of Medicine, University of Toronto, Toronto, Canada M5S 3M2.

Publikováno v: Chemical research in toxicology [Chem Res Toxicol] 2023 Nov 20; Vol. 36 (11), pp. 1711-1716. Date of Electronic Publication: 2023 Nov 03.

Idiosyncratic drug reactions: the reactive metabolite syndromes.

Autor: Knowles SR (AUTHOR), Uetrecht J (AUTHOR), Shear NH (AUTHOR)

Publikováno v: Lancet. 11/4/2000, Vol. 356 Issue 9241, p1587-1591. 5p.