On the Hunt for the Histone Code.

Autor: Ueberheide BM; Proteomics Laboratory, Division of Advanced Research Technologies, Department of Biochemistry and Molecular Pharmacology, Department of Neurology, New York University Langone Health Center, New York, NY, 10016, USA., Mollah S; SCIEX, Redwood City, CA, USA., Garcia BA; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA.

Publikováno v: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2024 Nov 01, pp. 100873. Date of Electronic Publication: 2024 Nov 01.

Using Constellation Pharmacology to Characterize a Novel α-Conotoxin from Conus ateralbus .

Autor: Neves JLB; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR-LA), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Urcino C; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Chase K; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Dowell C; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Hone AJ; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.; Mental Illness Research Education and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA., Morgenstern D; Departments of Biochemistry and Molecular Pharmacology, New York University Langone Medical Center, New York, NY 10016, USA., Chua VM; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Ramiro IBL; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.; The Marine Science Institute, University of the Philippines, Quezon City 1101, Philippines., Imperial JS; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Leavitt LS; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Phan J; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Fisher FA; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Watkins M; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Raghuraman S; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Tun JO; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Ueberheide BM; Departments of Biochemistry and Molecular Pharmacology, New York University Langone Medical Center, New York, NY 10016, USA., McIntosh JM; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.; Department of Psychiatry, University of Utah, Salt Lake City, UT 84108, USA.; Mental Health Department, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA., Vasconcelos V; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR-LA), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.; Faculty of Sciences, University of Porto, Rua do Campo Alegre, 4169-007 Porto, Portugal., Olivera BM; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Gajewiak J; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.

Publikováno v: Marine drugs [Mar Drugs] 2024 Feb 29; Vol. 22 (3). Date of Electronic Publication: 2024 Feb 29.

The γδ IEL effector API5 masks genetic susceptibility to Paneth cell death.

Autor: Matsuzawa-Ishimoto Y; Kimmel Center for Biology and Medicine at the Skirball Institute, New York University Grossman School of Medicine, New York, NY, USA.; Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA., Yao X; Kimmel Center for Biology and Medicine at the Skirball Institute, New York University Grossman School of Medicine, New York, NY, USA.; Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA., Koide A; Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Ueberheide BM; Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.; Proteomics Laboratory, Division of Advanced Research Technologies, New York University Grossman School of Medicine, New York, NY, USA.; Department of Neurology, New York University Grossman School of Medicine, New York, NY, USA., Axelrad JE; Division of Gastroenterology and Hepatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA., Reis BS; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA., Parsa R; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA., Neil JA; Kimmel Center for Biology and Medicine at the Skirball Institute, New York University Grossman School of Medicine, New York, NY, USA.; Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA., Devlin JC; Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA., Rudensky E; Kimmel Center for Biology and Medicine at the Skirball Institute, New York University Grossman School of Medicine, New York, NY, USA.; Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA., Dewan MZ; Experimental Pathology, Division of Advanced Research Technologies, New York University Grossman School of Medicine, New York, NY, USA., Cammer M; Microscopy Laboratory, Division of Advanced Research Technologies, New York University Grossman School of Medicine, New York, NY, USA., Blumberg RS; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Ding Y; Department of Laboratory Medicine, Geisinger Health, Danville, PA, USA., Ruggles KV; Institute for Systems Genetics, New York University Grossman School of Medicine, New York, NY, USA.; Division of Translational Medicine, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA., Mucida D; Department of Neurology, New York University Grossman School of Medicine, New York, NY, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA., Koide S; Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA. Shohei.Koide@nyulangone.org.; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA. Shohei.Koide@nyulangone.org., Cadwell K; Kimmel Center for Biology and Medicine at the Skirball Institute, New York University Grossman School of Medicine, New York, NY, USA. Ken.Cadwell@med.nyu.edu.; Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA. Ken.Cadwell@med.nyu.edu.; Division of Gastroenterology and Hepatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA. Ken.Cadwell@med.nyu.edu.

Publikováno v: Nature [Nature] 2022 Oct; Vol. 610 (7932), pp. 547-554. Date of Electronic Publication: 2022 Oct 05.

Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM.

Autor: Lanz TV; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Neurology, Mannheim Center for Translational Neurosciences (MCTN), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.; Department of Neurology and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; The Geriatric Research, Education, and Clinical Center (GRECC), VA Palo Alto Health Care System, Palo Alto, CA, USA., Brewer RC; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; The Geriatric Research, Education, and Clinical Center (GRECC), VA Palo Alto Health Care System, Palo Alto, CA, USA., Ho PP; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Beckman Center for Molecular Medicine, Stanford, CA, USA., Moon JS; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; The Geriatric Research, Education, and Clinical Center (GRECC), VA Palo Alto Health Care System, Palo Alto, CA, USA., Jude KM; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Beckman Center for Molecular Medicine, Stanford, CA, USA., Fernandez D; Macromolecular Structure Knowledge Center, Stanford ChEM-H Institute, Stanford, CA, USA., Fernandes RA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Beckman Center for Molecular Medicine, Stanford, CA, USA., Gomez AM; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; The Geriatric Research, Education, and Clinical Center (GRECC), VA Palo Alto Health Care System, Palo Alto, CA, USA., Nadj GS; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; The Geriatric Research, Education, and Clinical Center (GRECC), VA Palo Alto Health Care System, Palo Alto, CA, USA., Bartley CM; Weill Institute for Neurosciences, Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA, USA., Schubert RD; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA., Hawes IA; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA., Vazquez SE; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA., Iyer M; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA., Zuchero JB; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA., Teegen B; Institute of Experimental Immunology, Euroimmun AG, Lubeck, Germany., Dunn JE; Division of Neuroimmunology, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA., Lock CB; Division of Neuroimmunology, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA., Kipp LB; Division of Neuroimmunology, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA., Cotham VC; Department of Biochemistry and Molecular Pharmacology, NYU Perlmutter Cancer Center, NYU School of Medicine, New York, NY, USA.; NYU Langone Health Proteomics Laboratory, Division of Advanced Research Technologies, NYU School of Medicine, New York, NY, USA., Ueberheide BM; Department of Biochemistry and Molecular Pharmacology, NYU Perlmutter Cancer Center, NYU School of Medicine, New York, NY, USA.; NYU Langone Health Proteomics Laboratory, Division of Advanced Research Technologies, NYU School of Medicine, New York, NY, USA., Aftab BT; Preclinical Science and Translational Medicine, Atara Biotherapeutics, South San Francisco, CA, USA., Anderson MS; Department of Medicine, Diabetes Center, University of California San Francisco, San Francisco, CA, USA., DeRisi JL; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub, University of California San Francisco, San Francisco, CA, USA., Wilson MR; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA., Bashford-Rogers RJM; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Platten M; Department of Neurology, Mannheim Center for Translational Neurosciences (MCTN), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.; Department of Neurology and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; DKTK Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Garcia KC; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Beckman Center for Molecular Medicine, Stanford, CA, USA., Steinman L; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Beckman Center for Molecular Medicine, Stanford, CA, USA., Robinson WH; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. wrobins@stanford.edu.; The Geriatric Research, Education, and Clinical Center (GRECC), VA Palo Alto Health Care System, Palo Alto, CA, USA. wrobins@stanford.edu.

Publikováno v: Nature [Nature] 2022 Mar; Vol. 603 (7900), pp. 321-327. Date of Electronic Publication: 2022 Jan 24.

Decoy exosomes provide protection against bacterial toxins.

Autor: Keller MD; Department of Microbiology, New York University School of Medicine, New York, NY, USA.; Kimmel Center for Biology and Medicine at the Skirball Institute, New York University School of Medicine, New York, NY, USA., Ching KL; Department of Microbiology, New York University School of Medicine, New York, NY, USA.; Kimmel Center for Biology and Medicine at the Skirball Institute, New York University School of Medicine, New York, NY, USA., Liang FX; Division of Advanced Research Technologies, New York University Langone Health, New York, NY, USA.; The Microscopy Labratory at New York University Langone Health, New York, NY, USA., Dhabaria A; Division of Advanced Research Technologies, New York University Langone Health, New York, NY, USA.; The Proteomics Labratory at New York University Langone Health, New York, NY, USA., Tam K; Department of Microbiology, New York University School of Medicine, New York, NY, USA., Ueberheide BM; Division of Advanced Research Technologies, New York University Langone Health, New York, NY, USA.; The Proteomics Labratory at New York University Langone Health, New York, NY, USA.; The Laura and Isaac Perlmutter Cancer Center, New York, NY, USA., Unutmaz D; Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Torres VJ; Department of Microbiology, New York University School of Medicine, New York, NY, USA. Victor.Torres@nyulangone.org., Cadwell K; Department of Microbiology, New York University School of Medicine, New York, NY, USA. Ken.Cadwell@nyulangone.org.; Kimmel Center for Biology and Medicine at the Skirball Institute, New York University School of Medicine, New York, NY, USA. Ken.Cadwell@nyulangone.org.; Division of Gastroenterology and Hepatology, Department of Medicine, New York University Langone Health, New York, NY, USA. Ken.Cadwell@nyulangone.org.

Publikováno v: Nature [Nature] 2020 Mar; Vol. 579 (7798), pp. 260-264. Date of Electronic Publication: 2020 Mar 04.