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Mutator Foci Are Regulated by Developmental Stage, RNA, and the Germline Cell Cycle in Caenorhabditis elegans.

Autor: Uebel, Celja J.¹, Agbede, Dana¹, Wallis, Dylan C.¹, Phillips, Carolyn M.¹ cphil@usc.edu

Publikováno v: G3: Genes | Genomes | Genetics. Oct2020, Vol. 10 Issue 10, p3719-3728. 10p.

SIMR foci are found in the progenitor germ cells of C. elegans embryos

Autor: Uebel, Celja J., Manage, Kevin I., Phillips, Carolyn M.

Publikováno v: microPublication Biology

Multiple condensates occupy the perinuclear space of C. elegans germ cells, where they coordinate RNA surveillance to ensure proper gene expression (Lev and Rechavi 2020; Sundby et al. 2021). The most well-studied of these condensates are P granules,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509678b2e28f85b619a5bdbbe4f2d7ee

Caenorhabditis elegans germ granules are present in distinct configurations that differentially associate with RNAi-targeted RNAs.

Autor: Uebel CJ; Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089.; Present address: Departments of Developmental Biology and Genetics, Stanford University School of Medicine, Stanford CA, 94305., Rajeev S; Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089., Phillips CM; Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 25. Date of Electronic Publication: 2023 May 25.

A tudor domain protein, SIMR-1, promotes siRNA production at piRNA-targeted mRNAs in C. elegans .

Autor: Manage KI; Department of Biological Sciences, University of Southern California, Los Angeles, United States., Rogers AK; Department of Biological Sciences, University of Southern California, Los Angeles, United States., Wallis DC; Department of Biological Sciences, University of Southern California, Los Angeles, United States., Uebel CJ; Department of Biological Sciences, University of Southern California, Los Angeles, United States., Anderson DC; Department of Biological Sciences, University of Southern California, Los Angeles, United States., Nguyen DAH; Department of Biological Sciences, University of Southern California, Los Angeles, United States., Arca K; Department of Biological Sciences, University of Southern California, Los Angeles, United States., Brown KC; Department of Biology, Colorado State University, Fort Collins, United States.; Cell and Molecular Biology Program, Colorado State University, Fort Collins, United States., Cordeiro Rodrigues RJ; Biology of Non-coding RNA Group, Institute of Molecular Biology, Mainz, Germany.; International PhD Programme on Gene Regulation, Epigenetics, and Genome Stability, Mainz, Germany., de Albuquerque BF; Biology of Non-coding RNA Group, Institute of Molecular Biology, Mainz, Germany., Ketting RF; Biology of Non-coding RNA Group, Institute of Molecular Biology, Mainz, Germany., Montgomery TA; Department of Biology, Colorado State University, Fort Collins, United States., Phillips CM; Department of Biological Sciences, University of Southern California, Los Angeles, United States.

Publikováno v: ELife [Elife] 2020 Apr 27; Vol. 9. Date of Electronic Publication: 2020 Apr 27.