Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Udo Toebben"'
Autor:
Alison Rinderspacher, Michael Wyler, Stephan C. Schürer, Yuli Xie, Nathalie Aulner, Dusica Vidovic, Udo Toebben, Lars Branden, Gangli Gong, Yan Feng, Deborah H. Smith, Zhengxiang Zhu, Donald W. Landry, Yidong Liu, Shi Xian Deng, Yufei Tang, Caty Chung
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1191-1194
An IKKbeta inhibitor reported to block NF-kappaB transcriptional activities in Jurkat T cells, was found to enhance NF-kappaB translocation in HUVEC cells. These studies suggested a noncanonical NF-kappaB signaling pathway independent of IKKbeta in H
Autor:
Udo Toebben, Yuli Xie, Deborah H. Smith, Effie Tzilianos, Donald W. Landry, Lars Branden, Gangli Gong, Shi Xian Deng, Stephan C. Schürer, Lutz Tautz, Alison Rinderspacher, Yidong Liu, Dusica Vidovic, Caty Chung
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(9)
We report here a class of thiazolidine-2,4-diones and 2-thioxothiazolidin-4-ones as potent inhibitors of the lymphoid specific tyrosine phosphatase (Lyp) identified from high throughput screens. Chemical modification by incorporating the known phosph