M1 and M3 muscarinic receptors may play a role in the neurotoxicity of anhydroecgonine methyl ester, a cocaine pyrolysis product.

Autor: Garcia RC; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000, São Paulo/SP, Brazil.; Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of São Paulo, Rua São Nicolau, 210, 1° andar, 09913-030, Diadema/SP, Brazil.; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37212, USA.; Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center, 2201 West End Avenue, 1205 Light Hall, 37232-0697, Nashville/TN, USA., Dati LM; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000, São Paulo/SP, Brazil., Torres LH; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000, São Paulo/SP, Brazil., da Silva MA; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000, São Paulo/SP, Brazil., Udo MS; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000, São Paulo/SP, Brazil., Abdalla FM; Laboratory of Pharmacology, Butantan Institute, Av. Vital Brasil, 1500, 05503-900, São Paulo/SP, Brazil., da Costa JL; Criminalistic Institute of São Paulo, Rua Moncorvo Filho, 410, 05507-060, São Paulo/SP, Brazil., Gorjão R; Institute of Physical Activity Sciences and Sports, Post-Graduate Program in Human Movement Sciences, Cruzeiro do Sul University, São Paulo, Brazil., Afeche SC; Laboratory of Pharmacology, Butantan Institute, Av. Vital Brasil, 1500, 05503-900, São Paulo/SP, Brazil., Yonamine M; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000, São Paulo/SP, Brazil., Niswender CM; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37212, USA.; Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center, 2201 West End Avenue, 1205 Light Hall, 37232-0697, Nashville/TN, USA., Conn PJ; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37212, USA.; Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center, 2201 West End Avenue, 1205 Light Hall, 37232-0697, Nashville/TN, USA., Camarini R; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, Prédio 1, 05508-900, São Paulo/SP, Brazil., Sandoval MR; Laboratory of Pharmacology, Butantan Institute, Av. Vital Brasil, 1500, 05503-900, São Paulo/SP, Brazil., Marcourakis T; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000, São Paulo/SP, Brazil.

Publikováno v: Scientific reports [Sci Rep] 2015 Dec 02; Vol. 5, pp. 17555. Date of Electronic Publication: 2015 Dec 02.

Prenatal exposure to fipronil disturbs maternal aggressive behavior in rats.

Autor: Magalhães JZ; Undergraduate in Biological Science, Universidade Presbiteriana Mackenzie, São Paulo, Brazil. Electronic address: juliazaccam@gmail.com., Udo MS; Graduate Program of Toxicology and Toxicological Analysis in School of Pharmaceutical Science, University of São Paulo, São Paulo, Brazil., Sánchez-Sarmiento AM; Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil., Carvalho MP; Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil., Bernardi MM; Graduate Program of Environmental and Experimental Pathology and Graduate Program of Dentistry, Paulista University, São Paulo, Brazil., Spinosa HS; Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil.

Publikováno v: Neurotoxicology and teratology [Neurotoxicol Teratol] 2015 Nov-Dec; Vol. 52 (Pt A), pp. 11-6. Date of Electronic Publication: 2015 Sep 26.

Prenatal exposure to integerrimine N-oxide impaired the maternal care and the physical and behavioral development of offspring rats.

Autor: Sandini TM; Department of Clinical and Toxicological Analyses, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Dr. Lineu Prestes, 580, 05508-000 São Paulo, Brazil. Electronic address: thaisasandini@usp.br., Udo MS; Department of Clinical and Toxicological Analyses, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Dr. Lineu Prestes, 580, 05508-000 São Paulo, Brazil., Reis-Silva TM; Department of Neuroscience, Institute of Psychology, University of São Paulo, Av. Prof. Dr. Melo de Morais, 1721, 05508-030 São Paulo, Brazil., Bernardi MM; Graduate Program of Environmental and Experimental Pathology and Graduate Program Dentistry, Paulista University, UNIP, Rua Dr. Bacelar, 1212, 04026-002 São Paulo, Brazil., Spinosa Hde S; Department of Pathology, School of Veterinary Medicine, University of Sao Paulo, Av. Prof. Dr. Orlando Marques de Paiva, 87, 05508 270 São Paulo, Brazil.

Publikováno v: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience [Int J Dev Neurosci] 2014 Aug; Vol. 36, pp. 53-63. Date of Electronic Publication: 2014 May 29.