Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Udo Löhrs"'
Publikováno v:
Zentralblatt für Chirurgie. 133:582-589
PURPOSE: Since more than a century elective radical dissection of regional lymph nodes is a standard procedure in tumour surgery. We discuss whether or not this standard is still up to date. METHODS: The discussion was based on evaluations from well
Publikováno v:
Gynecologic Oncology. 103:883-887
Objective. Mutations of BRAF, a downstream mediator of K-RAS, have been described in serous borderline tumors of the ovary. Data concerning other types of ovarian tumors are scarce. Therefore, we assessed KRAS and BRAF mutation in a series of more th
Autor:
Veronika Kanitz, Birgit Anderegg, Gudrun Amann, Joachim Diebold, Jutta Engel, Udo Löhrs, Doris Mayr, Beate Luthardt
Publikováno v:
American Journal of Clinical Pathology. 126:101-109
To identify oncogene amplification involved in ovarian carcinogenesis, we studied 21 ovarian carcinomas and 5 serous borderline tumors using conventional comparative genomic hybridization (CGH) and CGH to a genomic DNA microarray. Immunohistochemical
Autor:
Jutta Engel, Udo Löhrs, Doris Mayr, Alexander Burges, Veronika Kanitz, Joachim Diebold, Gudrun Amann
Publikováno v:
Histopathology. 48:149-156
Aims : Data on HER-2/neu overexpression, its correlation to prognosis and the success of treatment with Herceptin® in ovarian carcinomas are scarce and contradictory. Therefore we assessed HER-2/neu expression and amplification in a large series of
Autor:
Annett Markwarth, Lyudmyla Dobryden, Udo Löhrs, Michael Haase, Andrea Tannapfel, Daniela Aust, Christian Wittekind, Gustavo B. Baretton
Publikováno v:
International Journal of Cancer. 115:673-677
The Raf/MEK/ERK (MAPK) signal transduction cascade is an important mediator of a number of cellular fates including growth, proliferation and survival. The BRAF gene is activated by oncogenic Ras, leading to cooperative effects in cells responding to
Autor:
Stephan Ihrler, Matthias Rössle, Andrea Sendelhofert, John Harrison, Udo Löhrs, Sabine Blasenbreu-Vogt
Publikováno v:
Virchows Archiv. 444:356-361
The understanding of regeneration in salivary glands as a finely tuned balance of cellular proliferation, differentiation and apoptosis has been limited by the difficulty of identifying proliferating cells. This has been overcome in the present inves
Publikováno v:
Der Pathologe. 25:116-119
Die so genannte intimo-intimale Intussuszeption bei zirkumferenter Aortendissektion ist eine sehr seltene Verlaufsform eines disseziierten Aortenaneurysmas, bei welcher der abgeloste Gefasschlauch durch den Blutstrom umgestulpt und nach distal in das
Publikováno v:
Modern Pathology. 17:277-287
Fluorescence in situ hybridization (FISH) is the most widely used technique to detect HER-2/neu gene amplification; however, it is only available in some institutions. In contrast, chromogenic in situ hybridization (CISH) can be evaluated by routine
Publikováno v:
Journal of Hematotherapy & Stem Cell Research. 12:359-366
Recent studies have convincingly demonstrated that adult bone marrow contains cells capable of differentiating into a variety of cell types. To investigate whether such bone marrow-derived cells participate on self-renewal and proliferation of nonhem
Autor:
Ralf Lichtinghagen, Clarissa Allmacher, Andreas G. Nerlich, Udo Löhrs, Annette Lebeau, Ulrich Sauer, Claudia Müller-Aufdemkamp
Publikováno v:
Journal of Molecular Histology. 35:443-455
The expression of matrix metalloproteinases (MMPs) with type IV collagenase activity has been associated with tumour invasion and metastatic potential in experimental models. We studied whether the cellular localization of MMP expression provides use