Triosephosphate-Isomerase Deficiency: Epiphenomenon or Cause of Loin Pain Haematuria Syndrome?

Autor: Hans-Joachim Schurek, Peter Maisel, Udo Helmchen, Björn Reusch, Arnulf Pekrun

Publikováno v: Case Reports in Nephrology and Dialysis, Vol 12, Iss 3, Pp 226-233 (2022)

A 32-year-old male patient presented the clinical picture of loin pain haematuria syndrome with pain attacks accompanied by macrohaematuria. In renal biopsy, the preglomerular vessels showed segmental wall hyalinosis in the sense of low-grade nephros

Externí odkaz: https://doaj.org/article/3c44f4d92ba44702ab8832357ac5264f

Retrospective genetic analysis illustrates the spectrum of autosomal Alport syndrome in a case of living-related donor kidney transplantation

Autor: Friederike Petzold, Anette Bachmann, Carsten Bergmann, Udo Helmchen, Jan Halbritter

Publikováno v: BMC Nephrology, Vol 20, Iss 1, Pp 1-5 (2019)

Abstract Background Kidney transplantation is the treatment of choice in end-stage renal disease due to Alport syndrome (AS). However, the chances of finding an adequate living-related donor in AS are much worse compared to non-heritable conditions.

Externí odkaz: https://doaj.org/article/608823005032486ebb0b8de3ae5bf76c

Trends of renal diseases in Germany : review of a regional renal biopsy database from 1990 to 2013

Autor: Georg Schlieper, Jürgen Floege, J Riehl, Udo Helmchen, Sabine Ernst, Corinna M. Zink, Hermann Josef Gröne

Publikováno v: Clinical kidney journal : CKJ 12(6), 795-800 (2019). doi:10.1093/ckj/sfz023
Clinical kidney journal : CKJ 14(1), 462-462 (2021). doi:10.1093/ckj/sfz150
Clinical Kidney Journal

Clinical kidney journal : CKJ 12(6), 795-800 (2019). doi:10.1093/ckj/sfz023
Published by Oxford Univ. Press, Oxford

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7642caf23ded0ce2e29482622e0ea797
https://publications.rwth-aachen.de/record/784391

Smaller caliber renal arteries are a novel feature of uromodulin-associated kidney disease

Autor: Udo Helmchen, Andrzej Januszewicz, Lars Christian Rump, Aleksander Prejbisz, Dirk Blondin, Mieczysław Litwin, Ilona Michałowska, Lorenz Sellin, Joanna Matuszkiewicz-Rowińska, Magdalena Januszewicz, Jörg T. Epplen, Gabriele Dekomien, Elżbieta Szwench-Pietrasz, Dariusz Sajnaga, Andrzej Wiecek, Marcin Adamczak, Magdalena Woznowski

Publikováno v: Kidney International. 88:160-166

Hyperuricemia is very common in industrialized countries and known to promote vascular smooth muscle cell proliferation. Juvenile hyperuricemia is a hallmark of uromodulin-associated kidney disease characterized by progressive interstitial renal fibr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d59762450f0e16c50acfa607fa2f81
https://doi.org/10.1038/ki.2015.2

Thrombospondin Type-1 Domain-Containing 7A in Idiopathic Membranous Nephropathy

Autor: Rolf A.K. Stahl, Jon B. Klein, Guillaume Dolla, Barbara Seitz-Polski, Nicola M. Tomas, Hong Ma, Elion Hoxha, Laurence H. Beck, Anne-Sophie Dabert-Gay, Michael L. Merchant, Catherine Meyer-Schwesinger, Udo Helmchen, Gunther Zahner, David J. Salant, Delphine Debayle, Gérard Lambeau

Publikováno v: New England Journal of Medicine. 371:2277-2287

Background Idiopathic membranous nephropathy is an autoimmune disease. In approximately 70% of patients, it is associated with autoantibodies against the phospholipase A2 receptor 1 (PLA2R1). Antigenic targets in the remaining patients are unknown. M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de225061339eec5eb76f4565627ea682
https://doi.org/10.1056/nejmoa1409354