Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Udo Dr Albus"'
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 95:24-30
We investigated the cardioprotective effect of acute and chronic sodium hydrogen exchanger 1 (NHE-1) inhibition with cariporide under pathological conditions in rabbits fed an atherogenic diet (0.25% cholesterol, 3% coconut oil), an experimental mode
Autor:
Stefanie Dimmeler, Udo Dr Albus, Christian Ihling, Ulrike Weiland, Judith Haendeler, Hartmut Ruetten, Scholz Wolfgang, Andreas M. Zeiher
Publikováno v:
Cardiovascular Research. 45:671-678
Objective: Apoptosis of cardiomyocytes may contribute to ischemia–reperfusion injury. The role of nitric oxide (NO) in apoptosis is controversial. Therefore, we investigated the effect of NO synthase inhibition on apoptosis of cardiomyocytes during
Publikováno v:
Journal of Thrombosis and Thrombolysis. 8:61-70
Autor:
Udo Dr Albus, Wolfgang Dr Scholz
Publikováno v:
Cardiovascular Research. 29:184-188
Publikováno v:
British Journal of Pharmacology. 107:970-975
1. Angiotensin converting enzyme (ACE)-inhibitors have been demonstrated to be effective in the treatment of cardiac hypertrophy when used in antihypertensive doses. The aim of our one year study with an ACE-inhibitor in rats was to separate local ca
Autor:
Doris Gehring, Udo Dr Albus, Scholz Wolfgang, Heinrich Christian Englert, Bernward A. Schölkens, Ute Fürst, Bernd Rosenkranz, Klaus Wirth
Publikováno v:
European Journal of Pharmacology. 210:69-75
The smooth muscle relaxant effects of the novel potassium channel opener, HOE 234, were investigated in guinea pig airways and compared with those of lemakalim (BRL 38227). Both agents evoked concentration-related reduction in spontaneous tracheal to
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 364(1)
It has been argued that activation of KATP channels in the sarcolemmal membrane of heart muscle cells during ischemia provides an endogenous cardioprotective mechanism. In order to test whether the novel cardioselective KATP channel blocker HMR 1098
Autor:
Wolfgang Dr Scholz, Udo Dr Albus, Bernward A. Schölkens, H.J. Lang, Laurent Counillon, Wolfgang Linz, Heinz Gögelein, Weichert Andreas
Publikováno v:
Cardiovascular research. 29(2)
Objective: The aim was to characterise the new compound HOE642 as a selective and cardioprotective Na+/H+ exchange inhibitor in various models. Methods: The effect of HOE642 was tested in the osmotically activated Na+/H+ exchange of rabbit erythrocyt
Autor:
H.J. Lang, Wolfgang Linz, Wolfgang Dr Scholz, Bernward A. Schölkens, Udo Dr Albus, Piero A. Martorana, H.C. Englert
Publikováno v:
British journal of pharmacology. 109(2)
1. The benzoylguanidine derivative Hoe 694 ((3-methylsulphonyl-4- piperidino-benzoyl) guanidine methanesulphonate) was characterized as an inhibitor of Na+/H+ exchange in rabbit erythrocytes, rat platelets and bovine endothelial cells. The potency of
Autor:
Wolfgang Dr Scholz, Udo Dr Albus, Lang Hans Jochen, Bernward A. Schölkens, Wolfgang Linz, Piero A. Martorana
Publikováno v:
Journal of molecular and cellular cardiology. 24(7)
To investigate a possible protective role of Na + /H + exchange inhibition under ischemic conditions isolated rat hearts were subjected to regional ischemia and reperfusion. In these experiments all 6 untreated hearts suffered ventricular fibrillatio