Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Udo Bock"'
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2098 (2021)
Ungual formulations are regularly tested using human nails or animal surrogates in Franz diffusion cell experiments. Membranes sometimes less than 100 µm thick are used, disregarding the higher physiological thickness of human nails and possible fun
Externí odkaz:
https://doaj.org/article/d7ce3b32e7e24b8b96da04fc38ed7d76
Autor:
Julia Metz, Katharina Knoth, Henrik Groß, Claus-Michael Lehr, Carolin Stäbler, Udo Bock, Marius Hittinger
Publikováno v:
Pharmaceutics, Vol 10, Iss 2, p 56 (2018)
Hay fever is notoriously triggered when nasal mucosa is exposed to allergenic pollen. One possibility to overcome this pollen exposure may be the application of an ointment with physical protective effects. In this context, we have investigated Bepan
Externí odkaz:
https://doaj.org/article/aa1282fddcbb44228e8fee804fad129d
Publikováno v:
Contact Dermatitis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1978b69cb7f8ab93f528edf92505fdbb
https://doi.org/10.1111/cod.14324
https://doi.org/10.1111/cod.14324
Autor:
Mario T. Schellenberger, Udo Bock, Florian Groeber-Becker, Brunhilde Blömeke, Jennifer Hennen, Heike Walles
Publikováno v:
Toxicology in Vitro. 57:62-66
A key event of the adverse outcome pathway for skin sensitization is the activation of dendritic cells (DC). To be most close to the in vivo situation, we combined for the first time reconstructed human epidermis (RHE) in coculture with THP-1 cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd4ba3ca9ec082618de1984ed37e90b
https://doi.org/10.1016/j.tiv.2019.02.002
https://doi.org/10.1016/j.tiv.2019.02.002
Autor:
Ralf-Kilian Zäh, Udo Bock, Henrik Groß, Birgit Wiegand, Hans Smola, Katharina Knoth, Barbara Veldung, Marius Hittinger, Dominic Burgio, Claus-Michael Lehr
Publikováno v:
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
England
England
Background In vitro skin permeation experiments are highly relevant for pharmaceutical, cosmetic, agricultural developments, and regulatory evaluation. A key requirement is the skin barrier integrity, that is accompanied by an intact stratum corneum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1fc257cdfcfae1586a8fd11a6d7df2
https://pubmed.ncbi.nlm.nih.gov/33404151
https://pubmed.ncbi.nlm.nih.gov/33404151
Publikováno v:
The Open Ophthalmology Journal. 12:226-240
Purpose:To developin vitromethods to assess binding by sodium hyaluronate in eye drops to corneal surfaces.Methods:Two different, complementary corneal binding set-ups were developed. In a dynamicin vitromodel, confluent corneal epithelial cells (HCE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea2ebb78ee68f78db1ee1e93736d86d7
https://doi.org/10.2174/1874364101812010226
https://doi.org/10.2174/1874364101812010226
Autor:
Henrik Groß, Udo Bock, Katharina Knoth, Julia Katharina Metz, Marius Hittinger, Carolin Stäbler, Claus-Michael Lehr
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 10, Iss 2, p 56 (2018)
Pharmaceutics; Volume 10; Issue 2; Pages: 56
Pharmaceutics, Vol 10, Iss 2, p 56 (2018)
Pharmaceutics; Volume 10; Issue 2; Pages: 56
Hay fever is notoriously triggered when nasal mucosa is exposed to allergenic pollen. One possibility to overcome this pollen exposure may be the application of an ointment with physical protective effects. In this context, we have investigated Bepan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6fb09e94d679ec198972f8ec48380e6
https://hdl.handle.net/10033/621512
https://hdl.handle.net/10033/621512
Publikováno v:
The Open Ophthalmology Journal
Purpose: To develop in vitro methods to assess binding by sodium hyaluronate in eye drops to corneal surfaces. Methods: Two different, complementary corneal binding set-ups were developed. In a dynamic in vitro model, confluent corneal epithelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56de9175af980d5bcae7470f06a75a24
https://pubmed.ncbi.nlm.nih.gov/30159097
https://pubmed.ncbi.nlm.nih.gov/30159097
Publikováno v:
Arzneimittelforschung. 54:522-529
Ziel der vorliegendenden In-vitro-Studien und In-vivo-Studien war es, die Permeation und Penetration eines 2,5%-igen Ketoprofen (CAS 22071-15-4) Gels [Phardol® Schmerz-Gel (Test-D)] mit Permeation und Penetration zweier anderer Ketoprofen-Gele (Ref-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::163f41fdf80f2863033b38de95c06220
https://doi.org/10.1055/s-0031-1297007
https://doi.org/10.1055/s-0031-1297007
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 68:390-399
The objective of this study was to establish and validate an ex vivo human cervical tissue model appropriate for transport studies of molecular and especially nucleic acid based drugs. For that purpose conditions had to be established for a standardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae4c747ed1ddadc42ed7af30c478778
https://doi.org/10.1016/j.ejpb.2007.06.014
https://doi.org/10.1016/j.ejpb.2007.06.014