Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Udo, Többen"'
Autor:
Maria Laura Cremona, Ai Yamamoto, Udo Többen, Dusica Vidovic, Yuli Xie, Nathalie Aulner, Donald W. Landry, Caty Chung, Lars Branden, Gangli Gong, Katherine M. Myers, Alison Rinderspacher, Stephan C. Schürer, Yidong Liu, Monique Andersen, Shi Xian Deng
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1715-1717
A quinazoline that decreases polyglutamine aggregate burden in a cell-based assay was identified from a high-throughput screen of a chemical-compound library, provided by the NIH Molecular Libraries Small Molecule Repository (MLSMR). A structure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67daaa3c56cc2d76ef345cc1d9ff49ad
https://doi.org/10.1016/j.bmcl.2009.01.087
https://doi.org/10.1016/j.bmcl.2009.01.087
Autor:
Michael R, Wyler, Deborah H, Smith, Eftihia, Cayanis, Udo, Többen, Nathalie, Aulner, Thomas, Mayer
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 486
To understand signaling pathways in mammalian cells, cell-based assays are relatively new and extremely powerful tools. We have developed a battery of phenotypic assays to study signaling; two of them are described in detail in this chapter. A subset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25236628728efbdabf7fe323a963b4a4
https://pubmed.ncbi.nlm.nih.gov/19347614
https://pubmed.ncbi.nlm.nih.gov/19347614
Autor:
Thomas U. Mayer, Michael Wyler, Udo Többen, Deborah H. Smith, Nathalie Aulner, Eftihia Cayanis
Publikováno v:
Methods in Molecular Biology ISBN: 9781603275446
To understand signaling pathways in mammalian cells, cell-based assays are relatively new and extremely powerful tools. We have developed a battery of phenotypic assays to study signaling; two of them are described in detail in this chapter. A subset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2492cc6c46e00900cf2a889a79e0c877
https://doi.org/10.1007/978-1-60327-545-3_3
https://doi.org/10.1007/978-1-60327-545-3_3
Autor:
Peter D. Kelly, Geoffrey Barger, Bernd Jagla, Nathalie Aulner, Thomas U. Mayer, Deborah H. Smith, Michael Wyler, Matthew Beard, Lars Branden, James E. Rothman, Udo Többen
Cell‐based assays are powerful tools for drug discovery and provide insight into complex signal transduction pathways in higher eukaryotic cells. Information gleaned from assays that monitor a cellular phenotype can be used to elucidate the details
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b36a7263f562911e6fb54928a2b83a10
https://doi.org/10.1016/s0076-6879(06)14015-x
https://doi.org/10.1016/s0076-6879(06)14015-x
Autor:
Martin Wiedmann, Klaus van Leyen, Deborah H. Smith, Birgitta Beatrix, Yuka Hotokezaka, Hitoshi Hotokezaka, Udo Többen, Takashi Nakamura
Publikováno v:
The Journal of biological chemistry. 277(21)
eEF1A, the eukaryotic homologue of bacterial elongation factor Tu, is a well characterized translation elongation factor responsible for delivering aminoacyl-tRNAs to the A-site at the ribosome. Here we show for the first time that eEF1A also associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6334b83903d746e78bf17d474281a9e3
https://pubmed.ncbi.nlm.nih.gov/11893745
https://pubmed.ncbi.nlm.nih.gov/11893745