Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Udo, Schnitzbauer"'
Autor:
Cornelia Bieri, Arezoo Daryadel, Carla Bettoni, Eva-Maria Pastor-Arroyo, Udo Schnitzbauer, Nati Hernando, Carsten A. Wagner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Kidneys are key regulators of phosphate homeostasis. Biallelic mutations of the renal Na+/phosphate cotransporter SLC34A1/NaPi-IIa cause idiopathic infantile hypercalcemia, whereas monoallelic mutations were frequently noted in adults with k
Externí odkaz:
https://doaj.org/article/c93fb8d4d8034a898d5aac56981a28cf
Autor:
Larissa Kägi, Carla Bettoni, Eva M Pastor-Arroyo, Udo Schnitzbauer, Nati Hernando, Carsten A Wagner
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0195427 (2018)
The 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) together with parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23) regulates calcium (Ca2+) and phosphate (Pi) homeostasis, 1,25(OH)2D3 synthesis is mediated by hydroxylases of the cytochrome P4
Externí odkaz:
https://doaj.org/article/308c4f62e9c749f99cdd58a7a3deb963
Autor:
Nicole B. Kampik, Nicole Gehring, Udo Schnitzbauer, J. Christopher Hennings, Christian A. Hübner, Carsten A. Wagner
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 5, Pp 1566-1577 (2014)
Background: The Slc4 family of bicarbonate transporters consists of several members, many of which are highly expressed in the kidney and play an important role in acid-base homeostasis. Among them are Ae1 (Slc4a1) and Ae2 (Slc4a2). Another member, A
Externí odkaz:
https://doaj.org/article/78acaceebd2244c4a1d47b1a9140263d
Autor:
Arezoo Daryadel, Betül Haykir, Catharina J. Küng, Milica Bugarski, Carla Bettoni, Udo Schnitzbauer, Nati Hernando, Andrew M. Hall, Carsten A. Wagner
Dietary inorganic phosphate (Pi) modulates renal Pi reabsorption by regulating the expression of the NaPi-IIa and NaPi-IIc Pi transporters. Here, we aimed to clarify the role of several Pi-regulatory mechanisms including parathyroid hormone (PTH), fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f85a1566d0c4b79062528460e2c1c6
https://doi.org/10.5167/uzh-218005
https://doi.org/10.5167/uzh-218005
Autor:
Carsten A. Wagner, Joanne Marks, Eva María Pastor-Arroyo, Nati Hernando, Udo Schnitzbauer, Matthias Bürki, Carla Bettoni, Thomas Knöpfel
Publikováno v:
The Journal of Physiology. 599:1131-1150
Intestinal absorption of phosphate is stimulated by 1,25(OH)$_{2}$ vitamin D$_{3.}$ At least two distinct mechanisms underlie phosphate absorption in the gut, an active transcellular transport requiring the Na$^{+}$ /phosphate cotransporter NaPi-IIb/
Autor:
Carla Bettoni, Petra Seebeck, Arezoo Daryadel, Carsten A. Wagner, Udo Schnitzbauer, Max Gassmann, Luciano Natale
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Fibroblast Growth Factor 23 (FGF23) is a phosphaturic factor causing increased renal phosphate excretion as well as suppression of 1,25 (OH)2-vitamin D3. Highly elevated FGF23 can promote development of rickets and osteomalacia. We and others previou
Autor:
Cornelia Bieri, Arezoo Daryadel, Carla Bettoni, Eva-Maria Pastor-Arroyo, Udo Schnitzbauer, Nati Hernando, Carsten A. Wagner
Publikováno v:
Scientific reports. 12(1)
Kidneys are key regulators of phosphate homeostasis. Biallelic mutations of the renal Na+/phosphate cotransporter SLC34A1/NaPi-IIa cause idiopathic infantile hypercalcemia, whereas monoallelic mutations were frequently noted in adults with kidney sto
Autor:
Nadège Poncet, Carsten A. Wagner, Udo Schnitzbauer, Nati Hernando, Eva María Pastor-Arroyo, Thomas Knöpfel, Jürg Biber, Pedro Henrique Imenez Silva
Publikováno v:
Acta Physiologica. 230
AIM Several Na$^{+}$ -dependent phosphate cotransporters namely NaPi-IIb/SLC34A3, Pit-1/SLC20A1 and Pit-2/SLC20A2, are expressed at the apical membrane of enterocytes but their contribution to active absorption of phosphate is unclear. The aim of thi
Autor:
Nati, Hernando, Eva Maria, Pastor-Arroyo, Joanne, Marks, Udo, Schnitzbauer, Thomas, Knöpfel, Matthias, Bürki, Carla, Bettoni, Carsten A, Wagner
Publikováno v:
The Journal of physiologyReferences. 599(4)
Intestinal absorption of phosphate proceeds via an active/transcellular route mostly mediated by NaPi-IIb/Slc34a2 and a poorly characterized passive/paracellular pathway. Intestinal phosphate absorption and expression of NaPi-IIb are stimulated by 1,
Autor:
Eva M, Pastor-Arroyo, Thomas, Knöpfel, Pedro H, Imenez Silva, Udo, Schnitzbauer, Nadège, Poncet, Jürg, Biber, Carsten A, Wagner, Nati, Hernando
Publikováno v:
Acta physiologica (Oxford, England)REFERENCES. 230(2)
Several NaIntestinal epithelial Pit-2-deficient mice were generated by crossing floxed Pit-2 with villin-Cre mice. Mice were fed 2 weeks standard or low phosphate diets. Stool, urine, plasma and intestinal and renal tissue were collected. Concentrati