Zobrazeno 1 - 10
of 5 368
pro vyhledávání: '"Udayan A"'
Autor:
Samuel S. Boyd, Dakota R. Robarts, Khue Nguyen, Maite Villar, Ibtihal M. Alghusen, Manasi Kotulkar, Aspin Denson, Halyna Fedosyuk, Stephen A. Whelan, Norman C.Y. Lee, John Hanover, Wagner B. Dias, Ee Phie Tan, Steven R. McGreal, Antonio Artigues, Russell H. Swerdlow, Jeffrey A. Thompson, Udayan Apte, Chad Slawson
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102060- (2024)
Objective: Pharmacologic or genetic manipulation of O-GlcNAcylation, an intracellular, single sugar post-translational modification, are difficult to interpret due to the pleotropic nature of O-GlcNAc and the vast signaling pathways it regulates. Met
Externí odkaz:
https://doaj.org/article/31c888e58b7d4df9804ebed3402bf348
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/d5776b3290aa43cea8b49962e533af5a
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundHepatocyte nuclear factor 4 alpha (HNF4α) is the master regulator of hepatic differentiation. Recent studies have also revealed the role of HNF4α in hepatocyte proliferation via negatively regulating the expression of proto-mitogenic gene
Externí odkaz:
https://doaj.org/article/aac9269bc8e24f43a2f589beecdc3d06
Autor:
Diego Paine‐Cabrera, Lisa K. Harvey, Dakota R. Robarts, Michele T. Pritchard, John Thyfault, Steven A. Weinman, Udayan Apte, Voytek Slowik
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 12, Pp 2719-2728 (2023)
Abstract Non‐alcoholic fatty liver disease (NAFLD), newly renamed metabolic dysfunction‐associated liver disease (MASLD), is a leading cause of liver disease in children and adults. There is a paucity of data surrounding potential biomarkers and
Externí odkaz:
https://doaj.org/article/5f10513adf2048eea5c613c1608d2926
Publikováno v:
Livers, Vol 3, Iss 3, Pp 331-346 (2023)
Congenital hepatic fibrosis/Autosomal recessive polycystic kidney disease (CHF/ARPKD) is an inherited neonatal disease induced by mutations in the PKHD1 gene and characterized by cysts and robust pericystic fibrosis in the liver and kidneys. The PCK
Externí odkaz:
https://doaj.org/article/8573c72cabd44c818e49c336e22ee0af
Autor:
Bharat Bhushan, Udayan Apte
Publikováno v:
Livers, Vol 3, Iss 2, Pp 300-309 (2023)
Liver regeneration is a compensatory response to tissue injury and loss. It is known that liver regeneration plays a crucial role in recovery following acetaminophen (APAP)-induced hepatotoxicity, which is the major cause of acute liver failure (ALF)
Externí odkaz:
https://doaj.org/article/2489e0637aa0481f9111b84fe9cb9f89
Autor:
Udayan Apte
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 505-506 (2024)
Externí odkaz:
https://doaj.org/article/cdf3571885e3470f8adad2ccf75a5eaa
Publikováno v:
Toxics, Vol 11, Iss 12, p 963 (2023)
Per- and poly-fluoroalkyl substances (PFAS) are a large class of fluorinated carbon chains that include legacy PFAS, such as perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), and perfluorohexane sulfonate
Externí odkaz:
https://doaj.org/article/64aa44cdcf8644ee8e346d841123621f
Autor:
Dakota R. Robarts, Steven R. McGreal, David S. Umbaugh, Wendena S. Parkes, Manasi Kotulkar, Sarah Abernathy, Norman Lee, Hartmut Jaeschke, Sumedha Gunewardena, Stephen A. Whelan, John A. Hanover, Natasha E. Zachara, Chad Slawson, Udayan Apte
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1510-1529 (2022)
Background & Aims: The liver has a unique capacity to regenerate after injury in a highly orchestrated and regulated manner. Here, we report that O-GlcNAcylation, an intracellular post-translational modification regulated by 2 enzymes, O-GlcNAc trans
Externí odkaz:
https://doaj.org/article/ea3c4596c6654707b658a0f0be83e403
Reservoir computing (RC), is a class of computational methods such as Echo State Networks (ESN) and Liquid State Machines (LSM) describe a generic method to perform pattern recognition and temporal analysis with any non-linear system. This is enabled
Externí odkaz:
http://arxiv.org/abs/2411.11414
