Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Uday R. Khire"'
Autor:
Uday R. Khire, Liang-Chuan Wang, Michael C. Milone, Sarah A. Richman, Edmund K. Moon, Steven M. Albelda
Publikováno v:
Mol Ther
Chimeric antigen receptor (CAR)-modified T cells are endowed with novel antigen specificity and are most often administered to patients without an engineered mechanism to control the CAR T cells once infused. “Suicide switches” such as the small
Publikováno v:
The Journal of Organic Chemistry. 60:544-549
Publikováno v:
Tetrahedron Letters. 34:15-18
A new reagent, 9-allenyl-9-BBN (1), has been developed for the convenient and efficient synthesis of a variety of homopropargylic alcohols via the
Publikováno v:
ChemInform. 22
Photolysis of the enones 4a–c leads to regioselective hydrogen abstraction and subsequent cyclization to furnish the spiro compounds 5a–d, which on further elaboration provide the spiro dione 6, a model for the antitumour antibiotic, fredericamyc
Publikováno v:
ChemInform. 24
A new reagent, 9-allenyl-9-BBN (1), has been developed for the convenient and efficient synthesis of a variety of homopropargylic alcohols via the
Publikováno v:
ChemInform. 26
Publikováno v:
ChemInform. 27
Autor:
Uday R. Khire, et al. et al.
Publikováno v:
ChemInform. 35
Autor:
Uday R, Khire, Donald, Bankston, James, Barbosa, David R, Brittelli, Yolanda, Caringal, Robert, Carlson, Jacques, Dumas, Todd, Gane, Sarah L, Heald, Barbara, Hibner, Jeffrey S, Johnson, Michael E, Katz, Nancy, Kennure, Jill, Kingery-Wood, Wendy, Lee, Xiao-Gao, Liu, Timothy B, Lowinger, Ian, McAlexander, Mary-Katherine, Monahan, Reina, Natero, Joel, Renick, Bernd, Riedl, Hong, Rong, Robert N, Sibley, Roger A, Smith, Donald, Wolanin
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(3)
Bis-aryl ureas have been disclosed previously as a potent class of Raf kinase inhibitors. Modifications in the amide portion led to an improvement in aqueous solubility, an important characteristic for an oral drug. Based on this finding, we hypothes