Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ubiquitins/metabolism"'
Autor:
Wenxia Wang, Swarna Bale, Jun Wei, Bharath Yalavarthi, Dibyendu Bhattacharyya, Jing Jing Yan, Hiam Abdala-Valencia, Dan Xu, Hanshi Sun, Roberta G. Marangoni, Erica Herzog, Sergejs Berdnikovs, Stephen D. Miller, Amr H. Sawalha, Pei-Suen Tsou, Kentaro Awaji, Takashi Yamashita, Shinichi Sato, Yoshihide Asano, Chinnaswamy Tiruppathi, Anjana Yeldandi, Bettina C. Schock, Swati Bhattacharyya, John Varga
Publikováno v:
Wang, W, Bale, S, Wei, J, Yalavarthi, B, Bhattacharyya, D, Yan, J J, Abdala-Valencia, H, Xu, D, Sun, H, Marangoni, R G, Herzog, E, Berdnikovs, S, Miller, S D, Sawalha, A H, Tsou, P-S, Awaji, K, Yamashita, T, Sato, S, Asano, Y, Tiruppathi, C, Yeldandi, A, Schock, B C, Bhattacharyya, S & Varga, J 2022, ' Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs ', Nature Communications, vol. 13, 6358 . https://doi.org/10.1038/s41467-022-33767-y
In addition to autoimmune and inflammatory diseases, variants of the TNFAIP3 gene encoding the ubiquitin-editing enzyme A20 are also associated with fibrosis in systemic sclerosis (SSc). However, it remains unclear how genetic factors contribute to S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a338b12062d469a0db07176e067af3
https://pure.qub.ac.uk/en/publications/8b36a497-37c9-40f4-b01a-2423feab81db
https://pure.qub.ac.uk/en/publications/8b36a497-37c9-40f4-b01a-2423feab81db
Autor:
Zhi Li, Benhur Lee, Ilhan Tezcan, Payam Tabarsi, Sofija Buta, Nahal Mansouri, Frederic Vigant, Domenico Tortorella, James Duehr, Béatrice Payelle-Brogard, Sandra Pellegrini, Li Qian, Scott D. Speer, Véronique Francois-Newton, Davood Mansouri, Jacob Piehler, Alexander N. Freiberg, Mark Hermann, Thomas J. Gardner, Marisela R. Rodriguez, Ozden Sanal, Tim Wedeking, Adolfo García-Sastre, Coralie F. Daussy, Deborah J. Lenschow, Erminia Rubino, Dusan Bogunovic
Publikováno v:
Nature communications, vol. 7, pp. 11496
Nature Communications
Nature Communications, Nature Publishing Group, 2016, 7, pp.11496. ⟨10.1038/ncomms11496⟩
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications, 2016, 7, pp.11496. ⟨10.1038/ncomms11496⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2016, 7, pp.11496. ⟨10.1038/ncomms11496⟩
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications, 2016, 7, pp.11496. ⟨10.1038/ncomms11496⟩
ISG15 is an interferon (IFN)-α/β-induced ubiquitin-like protein. It exists as a free molecule, intracellularly and extracellularly, and conjugated to target proteins. Studies in mice have demonstrated a role for Isg15 in antiviral immunity. By cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e5d1fd4382cc5fb25eff02fa341fa9
https://serval.unil.ch/resource/serval:BIB_8158D3B3AE00.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_8158D3B3AE00.P001/REF.pdf
The de novo synthesis of ubiquitin: Identification of deubiquitinases acting on ubiquitin precursors
Publikováno v:
Scientific Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Protein ubiquitination, a major post-translational modification in eukaryotes, requires an adequate pool of free ubiquitin. Cells maintain this pool by two pathways, both involving deubiquitinases (DUBs): recycling of ubiquitin from ubiquitin conjuga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88c7208f50f47172e6fd0e46a582ae1
https://repositorio-aberto.up.pt/handle/10216/117908
https://repositorio-aberto.up.pt/handle/10216/117908
Autor:
Jacob van den Born, Irene Otte-Höller, Lambert P. van den Heuvel, Marcel M. Verbeek, Guido David, Pieter Wesseling, Robert M.W. de Waal
Publikováno v:
The American Journal of Pathology, 155(6), 2115-2125. ELSEVIER SCIENCE INC
Heparan sulfate proteoglycans (HSPGs) have been suggested to play an important role in the formation and persistence of senile plaques and neurofibrillary tangles in dementia of the Alzheimer's type (DAT). We performed a comparative immunohistochemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e703e8a87b464350e2274435f01a243
https://doi.org/10.1016/s0002-9440(10)65529-0
https://doi.org/10.1016/s0002-9440(10)65529-0
Autor:
J Milner, M Molinari, L Bracco, Serge Carillo, Colette Salvat, Magali Pariat, Marc Piechaczyk, L Debüssche
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 1997, 17 (5), pp.2806--15. ⟨10.1128/MCB.17.5.2806⟩
Molecular and Cellular Biology, American Society for Microbiology, 1997, 17 (5), pp.2806--15. ⟨10.1128/MCB.17.5.2806⟩
International audience; p53 is a short-lived transcription factor that is frequently mutated in tumor cells. Work by several laboratories has already shown that the ubiquitin-proteasome pathway can largely account for p53 destruction, at least under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5a40a6b86375cd9536a9b39c5590d0
https://doi.org/10.1128/mcb.17.5.2806
https://doi.org/10.1128/mcb.17.5.2806
Autor:
Clémentine Schilte, Stephen Higgs, Matthew L. Albert, Alain Michault, Kristen Monte, Dana L. Vanlandingham, Deborah J. Lenschow, Arnaud Fontanet, Scott W. Werneke, Fernando Arenzana-Seisdedos, Anjali Rohatgi
Publikováno v:
PLoS Pathogens, Vol 7, Iss 10, p e1002322 (2011)
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2011, 7 (10), pp. e1002322. ⟨10.1371/journal.ppat.1002322⟩
PLoS Pathogens, 2011, 7 (10), pp. e1002322. ⟨10.1371/journal.ppat.1002322⟩
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2011, 7 (10), pp. e1002322. ⟨10.1371/journal.ppat.1002322⟩
PLoS Pathogens, 2011, 7 (10), pp. e1002322. ⟨10.1371/journal.ppat.1002322⟩
Chikungunya virus (CHIKV) is a re-emerging alphavirus that has caused significant disease in the Indian Ocean region since 2005. During this outbreak, in addition to fever, rash and arthritis, severe cases of CHIKV infection have been observed in inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749899add10a56a7295be9a4a094a400
http://europepmc.org/articles/PMC3197620?pdf=render
http://europepmc.org/articles/PMC3197620?pdf=render
A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58
Autor:
Yun Wah Lam, Belinda J. Westman, Angus I. Lamond, Edouard Bertrand, Céline Verheggen, Saskia Hutten
Publikováno v:
Molecular Cell
Molecular Cell; Vol 39
Molecular Cell, Elsevier, 2010, 39 (4), pp.618--31. ⟨10.1016/j.molcel.2010.07.025⟩
Molecular Cell; Vol 39
Molecular Cell, Elsevier, 2010, 39 (4), pp.618--31. ⟨10.1016/j.molcel.2010.07.025⟩
Summary Posttranslational SUMO modification is an important mechanism of regulating protein function, especially in the cell nucleus. The nucleolus is the subnuclear organelle responsible for rRNA synthesis, processing, and assembly of the large and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd66c346e200eeb42cdb8c21dedbbcfa
https://pubmed.ncbi.nlm.nih.gov/20797632
https://pubmed.ncbi.nlm.nih.gov/20797632
Autor:
Guillaume Bossis, M Brunet Simioni, Jacques Landry, Carmen Garrido, A de Thonel, Marc Piechaczyk, A Bouchot, Eric Fourmaux, Arlette Hammann, Anne-Laure Joly
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2009, 28 (37), pp.3332--44. ⟨10.1038/onc.2009.188⟩
Oncogene, Nature Publishing Group, 2009, 28 (37), pp.3332--44. ⟨10.1038/onc.2009.188⟩
Heat shock protein 27 (HSP27) accumulates in stressed cells and helps them to survive adverse conditions. We have already shown that HSP27 has a function in the ubiquitination process that is modulated by its oligomerization/phosphorylation status. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ca8305889246e5ef1c24c7b989cdb5
https://hal.archives-ouvertes.fr/hal-02194091
https://hal.archives-ouvertes.fr/hal-02194091
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2001, 20 (5), pp.551--62. ⟨10.1038/sj.onc.1204129⟩
Oncogene, 2001, 20 (5), pp.551--62. ⟨10.1038/sj.onc.1204129⟩
Oncogene, Nature Publishing Group, 2001, 20 (5), pp.551--62. ⟨10.1038/sj.onc.1204129⟩
Oncogene, 2001, 20 (5), pp.551--62. ⟨10.1038/sj.onc.1204129⟩
Cyclin C belongs to the cyclin family of proteins that control cell cycle transitions through activation of specific catalytic subunits, the cyclin-dependent kinases (CDKs). However, there is as yet no evidence for any role of cyclin C and its partne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cdffe4c43236f09d792135a066c681
https://hal.archives-ouvertes.fr/hal-02197302
https://hal.archives-ouvertes.fr/hal-02197302
Publikováno v:
The EMBO journal, Vol. 15, no. 18, p. 4884-99 (1996)
A library of random 10 residue peptides fused to the N-terminus of a reporter protein was screened in the yeast Saccharomyces cerevisiae for sequences that can target the reporter for degradation by the N-end rule pathway, a ubiquitin (Ub)-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac3e332270e4e757e98983f4af5956d
https://europepmc.org/articles/PMC452226/
https://europepmc.org/articles/PMC452226/