Zobrazeno 1 - 10
of 3 277
pro vyhledávání: '"Ubiquitin-like"'
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 10, Pp 1266-1272 (2024)
Objective·To explore the correlation between serum small ubiquitin-like modifier 1 (SUMO1) levels and hypertriglyceridemia in patients with type 2 diabetes mellitus (T2DM).Methods·A total of 239 newly diagnosed T2DM patients were recruited from the
Externí odkaz:
https://doaj.org/article/811cb208a82a49758b377463fd5f84f6
Autor:
Hiroshi Ageta, Tomoki Nishioka, Hisateru Yamaguchi, Kunihiro Tsuchida, Natsumi Ageta-Ishihara
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-6 (2024)
Abstract Discovery of novel post-translational modifications provides new insights into changes in protein function, localization, and stability. They are also key elements in understanding disease mechanisms and developing therapeutic strategies. We
Externí odkaz:
https://doaj.org/article/a54432df79d242768608ac1bede03286
Autor:
Weijie Li, Peirong Cao, Pengqi Xu, Fahui Sun, Chi Wang, Jiale Zhang, Shuqi Dong, Jon R. Wilson, Difei Xu, Hengxin Fan, Zhenhuan Feng, Xiaofei Zhang, Qingjun Zhu, Yingzhi Fan, Nick Brown, Neil Justin, Steven J Gamblin, He Li, Ying Zhang, Jun He
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Background Histone ubiquitination modification is emerging as a critical epigenetic mechanism involved in a range of biological processes. In vitro reconstitution of ubiquitinated nucleosomes is pivotal for elucidating the influence of histo
Externí odkaz:
https://doaj.org/article/66bacaeadfe845a89c52087ca1c0ba19
Autor:
Junfeng Liu, Xi Li, Jiawen Chen, Jingpei Guo, Hui Guo, Xiaoting Zhang, Jinming Fan, Ke Zhang, Junjie Mao, Bin Zhou
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Incomplete radiofrequency ablation (iRFA) in hepatocellular carcinoma (HCC) often leads to local recurrence and distant metastasis of the residual tumor. This is closely linked to the development of a tumor immunosuppressive envir
Externí odkaz:
https://doaj.org/article/d973367c4b204538818755ab3c0216ae
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-20 (2024)
Abstract Background Ubiquitin/ubiquitin-like (Ub/UBL)-related genes have been reported to be associated with the survival of osteosarcoma patients but have not yet been systematically explored. Methods The prognostic value of Ub/UBL-related genes, im
Externí odkaz:
https://doaj.org/article/c10118a2cc374120bd48f06c0178b6a4
Autor:
Ryota Hidese, Takayuki Ohira, Satsuki Sakakibara, Tsutomu Suzuki, Naoki Shigi, Shinsuke Fujiwara
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Ubiquitin-like proteins (Ubls) in eukaryotes and bacteria mediate sulfur transfer for the biosynthesis of sulfur-containing biomolecules and form conjugates with specific protein targets to regulate their functions. Here, we investigated the
Externí odkaz:
https://doaj.org/article/b08146a13223412686b501f5167a1172
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/27687c22db5d4add8f673150f0642df9
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151401- (2024)
The facultative intracellular bacterium Listeria (L.) monocytogenes may cause severe diseases in humans and animals. The control of listeriosis/L. monocytogenes requires the concerted action of cells of the innate and adaptive immune systems. In this
Externí odkaz:
https://doaj.org/article/28784aaf42334c0bb738fd2ea6f5e48f
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Proteases that cleave ubiquitin or ubiquitin-like proteins (UBLs) are critical players in maintaining the homeostasis of the organism. Concordantly, their dysregulation has been directly linked to various diseases, including cancer, neurodegeneration
Externí odkaz:
https://doaj.org/article/2e41aae0afde42369b911c547aa263d0