Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ubiquitin protein ligase NEDD4"'
Autor:
Kırmızıbayrak, Petek Ballar, Gözen, Oğuz, Erzurumlu, Yalçın, Barrio, R, Sutherland, JD, Rodriguez, MS
Proteostasis regulates key cellular processes such as cell proliferation, differentiation, transcription, and apoptosis. The mechanisms by which proteostasis is regulated are crucial and the deterioration of cellular proteostasis has been significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______9458::9417a90ad155f532ada7c63e64bf5b99
http://hdl.handle.net/11452/30992
http://hdl.handle.net/11452/30992
Autor:
Eugenio Sangiorgi, Beatrice Tropea, Maria Cristina De Rosa, Davide Pirolli, Benedetta Righino, Fiorella Gurrieri
Publikováno v:
Proceedings, Vol 22, Iss 1, p 10 (2019)
Among all the several targets in common use in the antitumor therapies, the pharmacologicinhibition of the MAPK (Mitogen Activated Protein Kinase) pathway represents an efficienttherapeutic approach [1]. [...]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1be5379606abba3cb4e1e523cb29c8
https://www.mdpi.com/2504-3900/22/1/10
https://www.mdpi.com/2504-3900/22/1/10
Publikováno v:
Molecular and cellular biology. 38(15)
CD133, a widely known marker of cancer stem cells, was recently found in extracellular vesicles. However, the mechanisms underlying CD133 translocation to the extracellular space remain largely unknown. Here we report that CD133 is monoubiquitinated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00859ca6d777e0f8a5575f3578e9f536
https://pubmed.ncbi.nlm.nih.gov/29760280
https://pubmed.ncbi.nlm.nih.gov/29760280
Publikováno v:
Biochemical Journal. 412:331-338
The tumour suppressor PTEN (phosphatase and tensin homologue deleted on chromosome 10; a phosphatidylinositol 3-phosphatase) is a multifunctional protein deregulated in many types of cancer. It is suggested that a number of proteins that relate with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27cdc2ef2842b106d6871ee512a7974
https://doi.org/10.1042/bj20071403
https://doi.org/10.1042/bj20071403
Autor:
Sharad Kumar, Sung-Hee Song, Craig Campbell, David I. Cook, Anuwat Dinudom, Margot L. Day, Il-Ha Lee
It has recently been shown that the epithelial Na(+) channel (ENaC) is compartmentalized in caveolin-rich lipid rafts and that pharmacological depletion of membrane cholesterol, which disrupts lipid raft formation, decreases the activity of ENaC. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31dc1ea8fc10054d7cc6b2047c6eeb1
https://hdl.handle.net/1959.8/154799
https://hdl.handle.net/1959.8/154799
Autor:
Konstantin Matentzoglu
Publikováno v:
Targeted Protein Database.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b97267c93e6d12233821e424c20e1f3f
https://doi.org/10.2970/tpdb.2007.92
https://doi.org/10.2970/tpdb.2007.92
Autor:
François Verrey, Olivier Staub
Publikováno v:
Journal of the American Society of Nephrology : JASN. 16(11)
The precise control of BP occurs via Na + homeostasis and involves the precise regulation of the epithelial Na + channel (ENaC) in the aldosterone-sensitive distal nephron. This has been corroborated by the linkage of mutations in the genes encoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461c87a04bfba9452b03448f27dd8fdd
https://pubmed.ncbi.nlm.nih.gov/16192418
https://pubmed.ncbi.nlm.nih.gov/16192418
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Cancer Cell. (1):10-21
The involvement of the homologous to E6-AP carboxyl terminus (HECT)-type E3s in crucial signaling pathways implicated in tumorigenesis is presently an area of intense research and extensive scientific interest. This review highlights recent discoveri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8898f4d98a1a76537e81846024c5c844
Autor:
Lei J; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China., Zheng F; Department of Physiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China., Chen L; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China., Zhang R; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China., Yang Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China., Yin Z; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, Jiangsu 210046, China., Luo L; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China.
Publikováno v:
Clinical science (London, England : 1979) [Clin Sci (Lond)] 2024 Jul 17; Vol. 138 (14), pp. 883-900.