Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ubiquitin/metabolism"'
Autor:
Pei Hsuan Wu, Phillip D. Zamore
Publikováno v:
Science
Molecular cell, Vol. 81, No 2 (2021) pp. 223-225
Molecular cell, Vol. 81, No 2 (2021) pp. 223-225
MicroRNAs (miRNAs) associate with Argonaute (AGO) proteins to direct widespread post-transcriptional gene repression. Although association with AGO typically protects miRNAs from nucleases, extensive pairing to some unusual target RNAs can trigger mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3c52437cc96db6de4698d5c68c3f1f
https://pubmed.ncbi.nlm.nih.gov/33184237
https://pubmed.ncbi.nlm.nih.gov/33184237
Publikováno v:
Biomolecules, Vol 11, Iss 54, p 54 (2021)
Biomolecules
Biomolecules
Protein homeostasis, or proteostasis, is crucial for the functioning of a cell, as proteins that are mislocalized, present in excessive amounts, or aberrant due to misfolding or other type of damage can be harmful. Proteostasis includes attaining the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd4380f50b7ad67d306f2e2d3754a68
https://www.mdpi.com/2218-273X/11/1/54
https://www.mdpi.com/2218-273X/11/1/54
Autor:
Aloysius Wong, Grégory Vert, Dario Monachello, Alexander W. Johnson, Natali Romero-Barrios, Ulla Dolde, Anne Cayrel, Claire Lurin, Hélène San Clemente
Publikováno v:
The Plant cell
The Plant cell, American Society of Plant Biologists (ASPB), 2020, 32 (1), pp.123-138. ⟨10.1105/tpc.19.00568⟩
The Plant cell, 2020, ⟨10.1105/tpc.19.00568⟩
The Plant cell, American Society of Plant Biologists (ASPB), 2020, ⟨10.1105/tpc.19.00568⟩
The Plant cell, American Society of Plant Biologists (ASPB), 2020, 32 (1), pp.123-138. ⟨10.1105/tpc.19.00568⟩
The Plant cell, 2020, ⟨10.1105/tpc.19.00568⟩
The Plant cell, American Society of Plant Biologists (ASPB), 2020, ⟨10.1105/tpc.19.00568⟩
The lack of resolution when studying the many different ubiquitin chain types found in eukaryotic cells has been a major hurdle to our understanding of their specific roles. We currently have very little insight into the cellular and physiological fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac75b82a257c4c1c72c75d675680bdb
https://hal.inrae.fr/hal-03347890
https://hal.inrae.fr/hal-03347890
Autor:
Emmanuel Lemichez, Brenda A. Schulman, Zhenyue Hao, Sachdev S. Sidhu, Nan Li, Ryan Murchie, Wei Zhang, Maria A. Sartori, Kuen-Phon Wu, Jason Moffat, John R. Walker, Avinash Persaud, Yi Sheng, Alban Ordureau, Jicheng Hu, Chong Jiang, Manjeet Mukherjee, Kevin R. Brown, Yufeng Tong, Yanjun Li, Junjie Chen, Anne Doye, Peter Y. Mercredi, Daniela Rotin, Hari B. Kamadurai, J. Wade Harper
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2016, 62 (1), pp.121-136. ⟨10.1016/j.molcel.2016.02.005⟩
Molecular Cell, Elsevier, 2016, 62 (1), pp.121-136. ⟨10.1016/j.molcel.2016.02.005⟩
Comment in : A Billion Ubiquitin Variants to Probe and Modulate the UPS. [Mol Cell. 2016]; International audience; HECT-family E3 ligases ubiquitinate protein substrates to control virtually every eukaryotic process and are misregulated in numerous d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0423280b3710b384d45c649c83c073
https://doi.org/10.1016/j.molcel.2016.02.005
https://doi.org/10.1016/j.molcel.2016.02.005
Autor:
Michel Strubin, Rudolf K. F. Beran, Laetitia Gerossier, Simon P. Fletcher, Christine M. Livingston, Fabien Abdul, Pieter C van Breugel, Henrik Mueller, Congrong Niu, Adrien Decorsiere, Olivier Hantz
Publikováno v:
Nature
Nature, Vol. 531, No 7594 (2016) pp. 386-389
Nature, Nature Publishing Group, 2016, 531 (7594), pp.386-389. ⟨10.1038/nature17170⟩
Nature, Vol. 531, No 7594 (2016) pp. 386-389
Nature, Nature Publishing Group, 2016, 531 (7594), pp.386-389. ⟨10.1038/nature17170⟩
Chronic hepatitis B virus infection is a leading cause of cirrhosis and liver cancer. Hepatitis B virus encodes the regulatory HBx protein whose primary role is to promote transcription of the viral genome, which persists as an extrachromosomal DNA c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64462e2ec856d32508eaa7900d6ba34d
http://archive-ouverte.unige.ch/unige:85682
http://archive-ouverte.unige.ch/unige:85682
Autor:
Hagmann, V, Sommer, S, Fabian, P, Bierlmeier, J, van Treel, N, Mootz, H, Schwarzer, D, Azevedo, JE, Dodt, G
Publikováno v:
Scientific Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Peroxisomal matrix proteins contain either a peroxisomal targeting sequence 1 (PTS1) or a PTS2 that are recognized by the import receptors PEX5 and PEX7, respectively. PEX5 transports the PTS1 proteins and the PEX7/PTS2 complex to the docking translo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::79ebb51d4a98a51b27821208dc565b67
https://pubmed.ncbi.nlm.nih.gov/30375424
https://pubmed.ncbi.nlm.nih.gov/30375424
Autor:
Mitsutero Ito, Jeremy N. Skepper, Syed Haider, Roger Foo, Kelvin See, M. Ackers-Johnson, Emma L. Robinson, H.L. Roderick, Nichola Figg, Anne C. Ferguson-Smith, Carmen Methner, Patrick Brien, Ana Vujic
Publikováno v:
Journal of Molecular and Cellular Cardiology, 82, 174-83. ELSEVIER SCI LTD
Differential DNA methylation exists in the epigenome of end-stage failing human hearts but whether it contributes to disease progression is presently unknown. Here, we report that cardiac specific deletion of Dnmt3b, the predominant DNA methyltransfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074fbaab3c4c5ce4cf5fd4a280dc1362
https://doi.org/10.1016/j.yjmcc.2015.03.007
https://doi.org/10.1016/j.yjmcc.2015.03.007
Autor:
Manuel P. Pinto, Andreia F. Carvalho, Tânia Francisco, Jorge E. Azevedo, Tony A. Rodrigues, Cláudia P. Grou
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PEX5 is the shuttling receptor for newly synthesized peroxisomal matrix proteins. Alone, or with the help of an adaptor protein, this receptor binds peroxisomal matrix proteins in the cytosol and transports them to the peroxisomal membrane docking/tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e310f1cb11c2960fa352b150baeffe25
https://doi.org/10.1016/j.biochi.2013.08.003
https://doi.org/10.1016/j.biochi.2013.08.003
Akademický článek
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Autor:
Marina Pantazopoulou, Zoi Erpapazoglou, Sébastien Léon, Francesca Giordano, Muriel Mari, Graça Raposo, Manel Dhaoui, Rosine Haguenauer-Tsapis, Fulvio Reggiori
Publikováno v:
Erpapazoglou, Z, Dhaoui, M, Pantazopoulou, M, Giordano, F, Mari, M, Léon, S, Raposo, G, Reggiori, F & Haguenauer-Tsapis, R 2012, ' A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting ', Molecular Biology of the Cell, vol. 23, no. 11, pp. 2170-83 . https://doi.org/10.1091/mbc.E11-10-0891
Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2012, 23 (11), pp.2170-2183. ⟨10.1091/mbc.E11-10-0891⟩
Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2012, 23 (11), pp.2170-2183. ⟨10.1091/mbc.E11-10-0891⟩
Many yeast and some mammalian multivesicular body (MVB) cargoes display modification by K63-linked ubiquitin chains (K63Ub), which are required for their efficient sorting. Yeast UBD-containing ESCRT proteins are modified by the ubiquitin ligase Rsp5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bfc26821218e0b5eaca1fdb230b478
https://doi.org/10.1091/mbc.e11-10-0891
https://doi.org/10.1091/mbc.e11-10-0891