Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ubiquilin 4"'
Autor:
Hongyu Ding, YongJie Xu, Ronggui Hu, Xiangyan Zhang, Hui Chen, Yingjie Nie, LiLing Gu, Runsang Pan, Yun Yang, Chuanyin Li, Fang Liu
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3738-3752 (2021)
Molecular Oncology
Molecular Oncology
ATM serine/threonine kinase (ATM; previously known as ataxia‐telangiectasia mutated) plays a critical role in maintaining genomic stability and regulates multiple downstream pathways, such as DNA repair, cell cycle arrest, and apoptosis. As a serin
Publikováno v:
Journal of Oncology, Vol 2021 (2021)
Journal of Oncology
Journal of Oncology
Recently, it was reported that ubiquilin 4 (UBQLN4) alteration was associated with genomic instability in some cancers. However, whether UBQLN4 is a valuable biomarker for the prognosis of immunotherapy in pan-cancer was not identified. We evaluated
Autor:
Matias A. Bustos, Sojun Hoshimoto, Ron D. Jachimowicz, Tomohiko Nishi, Yoshiaki Shoji, Dave S.B. Hoon, Yuko Kitagawa, Yosef Shiloh, Hiroya Takeuchi, Shu Ching Chang, Shigeshi Ono, Tomohiro Murakami
Publikováno v:
Mol Oncol
Molecular Oncology, Vol 15, Iss 4, Pp 1069-1087 (2021)
Molecular Oncology
Molecular Oncology, Vol 15, Iss 4, Pp 1069-1087 (2021)
Molecular Oncology
Resistance to standard cisplatin‐based chemotherapies leads to worse survival outcomes for patients with esophageal squamous cell carcinoma (ESCC). Therefore, there is an urgent need to understand the aberrant mechanisms driving resistance in ESCC
Autor:
Changzhi Huang, Hong Lin, Qing Chang, Jie Ding, Wenjie Wang, Mei Zhao, Dongdong Li, Jia Wang, Yan Li, Ning Zhou, Shengkai Huang, Wei Cui, Xin Dong
Publikováno v:
Medical Science Monitor. 24:3564-3570
BACKGROUND Ubiquilin-4 (UBQLN4) is a component of the ubiquitin-proteasome system and regulates the degradation of many proteins implicated in pathological conditions. The aim of this study was to determine the role of UBQLN4 in regulating the prolif
Autor:
Allison Brashear, Beverly M. Snively, Thomas C. Markello, Christopher T. Whitlow, Laurie J. Ozelius, Kathleen J. Sweadner, Jared F. Cook, Camilo Toro
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0151429 (2016)
PLoS ONE, Vol 11, Iss 3, p e0151429 (2016)
A 21-year old male presented with ataxia and dysarthria that had appeared over a period of months. Exome sequencing identified a de novo missense variant in ATP1A3, the gene encoding the α3 subunit of Na,K-ATPase. Several lines of evidence suggest t
Autor:
Vincent Lotteau, Beate M. Kümmerer, Lionel Tafforeau, Thérèse Couderc, Christian Drosten, Hans Henrik Gad, Patricia Cassonnet, Marc Lecuit, Yves Jacob, Frédéric Tangy, Mehdi Bouraï, Philippe Desprès, Delphine Judith, Marianne Lucas-Hourani, Patrice Andre, Pierre-Olivier Vidalain, Louis Jones
Publikováno v:
Journal of Virology
Journal of Virology, 2012, 86 (6), pp.3121-34. ⟨10.1128/JVI.06390-11⟩
Journal of Virology, American Society for Microbiology, 2012, 86 (6), pp.3121-34. ⟨10.1128/JVI.06390-11⟩
Journal of Virology, 2012, 86 (6), pp.3121-34. ⟨10.1128/JVI.06390-11⟩
Journal of Virology, American Society for Microbiology, 2012, 86 (6), pp.3121-34. ⟨10.1128/JVI.06390-11⟩
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that has been responsible for an epidemic outbreak of unprecedented magnitude in recent years. Since then, significant efforts have been made to better understand the biology of this viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49a77b478a95dcd2c853af0bbd8de05
https://europepmc.org/articles/PMC3302312/
https://europepmc.org/articles/PMC3302312/
Publikováno v:
The Journal of general virology. 91(Pt 11)
The small hydrophobic (SH) protein of mumps virus has been reported to interfere with innate immunity by inhibiting tumour necrosis factor alpha-mediated apoptosis. In a yeast two-hybrid screen we have identified the ataxin-1 ubiquitin-like interacti