Molecular and structural insights into the 5‐HT2C receptor as a therapeutic target for substance use disorders.

Autor: Ubhayarathna, Maleesha, Langmead, Christopher J., Diepenhorst, Natalie A., Stewart, Gregory D.

Publikováno v: British Journal of Pharmacology; Nov2024, Vol. 181 Issue 22, p4414-4429, 16p

Molecular and structural insights into the 5-HT 2C receptor as a therapeutic target for substance use disorders.

Autor: Ubhayarathna M; Drug Discovery Biology and Neuroscience & Mental Health Therapeutic Program Area, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia., Langmead CJ; Drug Discovery Biology and Neuroscience & Mental Health Therapeutic Program Area, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.; Neuromedicines Discovery Centre, Monash University, Parkville, Australia., Diepenhorst NA; Drug Discovery Biology and Neuroscience & Mental Health Therapeutic Program Area, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia., Stewart GD; Drug Discovery Biology and Neuroscience & Mental Health Therapeutic Program Area, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.; Neuromedicines Discovery Centre, Monash University, Parkville, Australia.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Nov; Vol. 181 (22), pp. 4414-4429. Date of Electronic Publication: 2023 Oct 02.