A COVID-19 vaccine candidate composed of SARS-CoV-2 RBD dimer and Neisseria meningitidis outer membrane vesicles

Autor: Darielys Santana-Mederos, Rocmira Perez-Nicado, Yanet Climent, Laura Rodriguez, Belinda Sanchez Ramirez, Sonia Perez-Rodriguez, Meybi Rodriguez, Claudia Labrada, Tays Hernandez, Marianniz Diaz, Ivette Orosa, Ubel Ramirez, Reynaldo Oliva, Raine Garrido, Felix Cardoso, Mario Landys, Roselyn Martinez, Humberto Gonzalez, Tamara Hernandez, Rolando Ochoa-Azze, Jose L. Perez, Juliet Enriquez, Nibaldo Gonzalez, Yenicet Infante, Luis A. Espinosa, Yassel Ramos, Luis Javier González, Carmen Valenzuela, Ana Victoria Casadesus, Briandy Fernandez, Gertrudis Rojas, Beatriz Pérez-Massón, Yaima Tundidor, Ernesto Bermudez, Claudia A. Plasencia, Tammy Boggiano, Eduardo Ojito, Fabrizio Chiodo, Sonsire Fernandez, Françoise Paquet, Cheng Fang, Guang-Wu Chen, Daniel G. Rivera, Yury Valdes-Balbin, Dagmar Garcia-Rivera, Vicente Verez Bencomo

Publikováno v: RSC Chemical Biology
RSC Chemical Biology, Royal Society of Chemistry, In press, ⟨10.1039/D1CB00200G⟩
Santana-Mederos, D, Perez-Nicado, R, Climent, Y, Rodriguez, L, Ramirez, B S, Perez-Rodriguez, S, Rodriguez, M, Labrada, C, Hernandez, T, Diaz, M, Orosa, I, Ramirez, U, Oliva, R, Garrido, R, Cardoso, F, Landys, M, Martinez, R, Gonzalez, H, Hernandez, T, Ochoa-Azze, R, Perez, J L, Enriquez, J, Gonzalez, N, Infante, Y, Espinosa, L A, Ramos, Y, González, L J, Valenzuela, C, Casadesus, A V, Fernandez, B, Rojas, G, Pérez-Massón, B, Tundidor, Y, Bermudez, E, Plasencia, C A, Boggiano, T, Ojito, E, Chiodo, F, Fernandez, S, Garcia-Rivera, D, Fang, C, Chen, G-W, Rivera, D G, Valdes-Balbin, Y, Garcia-Rivera, D & Verez Bencomo, V 2022, ' A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and : Neisseria meningitidis outer membrane vesicles ', RSC Chemical Biology, vol. 3, no. 2, pp. 242-249 . https://doi.org/10.1039/d1cb00200g
RSC Chemical Biology, 3(2), 242-249. Royal Society of Chemistry

SARS-CoV-2 infection is mediated by the interaction of the spike glycoprotein trimer via its receptor-binding domain (RBD) with the host's cellular receptor. Vaccines seek to block this interaction by eliciting neutralizing antibodies, most of which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ca97b53fb4a278f7101794d646b985
https://hal.archives-ouvertes.fr/hal-03519898

A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and

Autor: Darielys, Santana-Mederos, Rocmira, Perez-Nicado, Yanet, Climent, Laura, Rodriguez, Belinda Sanchez, Ramirez, Sonia, Perez-Rodriguez, Meybi, Rodriguez, Claudia, Labrada, Tays, Hernandez, Marianniz, Diaz, Ivette, Orosa, Ubel, Ramirez, Reynaldo, Oliva, Raine, Garrido, Felix, Cardoso, Mario, Landys, Roselyn, Martinez, Humberto, Gonzalez, Tamara, Hernandez, Rolando, Ochoa-Azze, Jose L, Perez, Juliet, Enriquez, Nibaldo, Gonzalez, Yenicet, Infante, Luis A, Espinosa, Yassel, Ramos, Luis Javier, González, Carmen, Valenzuela, Ana Victoria, Casadesus, Briandy, Fernandez, Gertrudis, Rojas, Beatriz, Pérez-Massón, Yaima, Tundidor, Ernesto, Bermudez, Claudia A, Plasencia, Tammy, Boggiano, Eduardo, Ojito, Fabrizio, Chiodo, Sonsire, Fernandez, Françoise, Paquet, Cheng, Fang, Guang-Wu, Chen, Daniel G, Rivera, Yury, Valdes-Balbin, Dagmar, Garcia-Rivera, Vicente, Verez Bencomo

Publikováno v: RSC chemical biology. 3(2)

SARS-CoV-2 infection is mediated by the interaction of the spike glycoprotein trimer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d46c348d7f1709d3efb5b5fdeb9aad0c
https://pubmed.ncbi.nlm.nih.gov/35360883

NMR line-fitting quantification of polysaccharide N- acylurea-based modification in glycoconjugates of Salmonella Typhi Vi polysaccharide

Autor: Raine Garrido, Vicente Vérez, Ubel Ramirez, Jean Pierre Soubal, Leonid Torres

Publikováno v: Magnetic Resonance in Chemistry. 55:720-723

The polysaccharides modification via carbodiimide reaction is one of the most applied methods for obtaining conjugated vaccines against Salmonella enterica. However, N-acylurea carbodiimide adduct generated in the process is a critical impurity in ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f4090eed37ff1dcf089ec0cc64eec67
https://doi.org/10.1002/mrc.4579

204. Evaluación de los resultados de cirugía cardíaca en pacientes octogenarios en los últimos 6 años

Autor: Ubel Ramirez, José María Mesa, R. Sánchez Pérez, E. González, L. Sartor, José Antonio Blázquez, A. Hurtado

Publikováno v: Cirugía Cardiovascular, Vol 19, Iss 2, p 235 (2012)

Objetivo Evaluar de forma retrospectiva los resultados de la cirugia cardiaca en pacientes mayores de 80 anos intervenidos desde el 1 de enero de 2006 – 1 de enero de 2012 y compararlos con los pacientes menores de 80 anos. Pacientes y metodos Anal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b983aa4136791480cd1a0b05a68f4886
http://www.sciencedirect.com/science/article/pii/S1134009612706071

168. Rentabilidad de la coronariografía no invasiva mediante angiotomografía computarizada coronaria en la valoración preoperatoria de pacientes que van a ser sometidos a cirugía cardíaca no coronaria

Autor: José Antonio Blázquez, Ubel Ramirez, L. Sartor, José María Mesa, Alicia Hurtado, J. Silvestre, R. Sánchez, E. González, Omar Al Razzo

Publikováno v: Cirugía Cardiovascular, Vol 19, Iss 2, p 183 (2012)

Objetivos La angiografia coronaria no invasiva mediante tomografia computarizada (ACTC) ha sido validada para descartar la presencia de enfermedad coronaria (EC) en pacientes que van a ser sometidos a cirugia cardiaca no coronaria. Analizamos la rent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b522368eb16b3f0120dbb3cca56e006