Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Ubasawa A"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1984 Dec 01. 81(23), 7495-7499.
Externí odkaz:
https://www.jstor.org/stable/24734
Autor:
Baba, Masanori, De Clercq, Erik, Tanaka, Hiromichi, Ubasawa, Masaru, Takashima, Hideaki, Sekiya, Kouichi, Nitta, Issei, Umezu, Kohei, Nakashima, Hideki, Mori, Shuichi, Shigeta, Shiro, Walker, Richard T., Miyasaka, Tadashi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1991 Mar . 88(6), 2356-2360.
Externí odkaz:
https://www.jstor.org/stable/2356381
Autor:
Masaru Ubasawa, Yoshiyuki Fujimura, Naoko Ueda, Hideaki Takashima, Satoshi Yuasa, Kouichi Sekiya, Naohiro Kamiya
Publikováno v:
Journal of Medicinal Chemistry. 45:3138-3142
Novel 2-amino-6-arylthio-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl) esters were synthesized and evaluated for antihepatitis B virus (HBV) activity in vitro using HB611, HuH-6 cell line, stably transfected with the HBV genome. Among
Publikováno v:
Nucleosides and Nucleotides. 17:2241-2247
An acyclonucleoside synthesis was investigated on the regioselective introduction of an acyclochain. We found that iodotrimethylsilane catalyzed the reaction of acyclochain introduction as well as its migration from S2 to N1 of 2-thiothymine and from
Publikováno v:
Proceedings of the Japan Academy, Series B. 74:169-173
Autor:
Aiko Ubasawa, Yukio Kiho
Publikováno v:
Nonlinear Analysis: Theory, Methods & Applications. 30:5395-5402
Publikováno v:
Proceedings of the Japan Academy, Series B. 73:74-78
Interaction between trypsin and its substrate, NDV-F, is investigated by two approaches, in which the natural sequence and the polar/non-polar sequence are used respectively. In the first approach that we call“stepwise recognition”, addition of t
Publikováno v:
Proceedings of the Japan Academy, Series B. 72:185-190
A unique nucleotide sequence that consists of aligned second bases of colon triplets in the cDNA sequence of trypsin is designed to identify the active sites on the DEV model. Compared with the amino acid sequence that was exploited before, the assig
Autor:
E. De Clercq, Kouichi Sekiya, M Ubasawa, Masanori Baba, H Walther, H Takashima, Peter P. Mager
Publikováno v:
European Journal of Medicinal Chemistry. 31:701-712
Summary The dioxypyrimidine ring of 5,6-substituted 1-[(2-hydroxyethoxy)methyl]uracils is an extended ‘partial π system’ with ring distortion. PM3-MM+ geometry optimization suggested a lipophilic ‘butterfly-like’ orientation which was also f
Autor:
Hiromichi Tanaka, Hideaki Takashima, Masaru Ubasawa, Kouichi Sekiya, Naoko Inouye, Masanori Baba, Shiro Shigeta, Richard T. Walker, Erik De Clercq, Tadashi Miyasaka
Publikováno v:
Journal of Medicinal Chemistry. 38:2860-2865