Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ubaradka G. Sathyanarayana"'
Autor:
Audrey Audetat, Chérie Tschida, Sarah Kreston, Adam Stephen, Brittany D’Alessio, Madeline Bondy, Leisa Jackson, Hestia Mellert, Niki Givens, Ubaradka G. Sathyanarayana, Gary A. Pestano
Publikováno v:
Diagnostics, Vol 12, Iss 3, p 729 (2022)
Liquid biopsies are an integral part of the diagnosis of cancer. Here, we have extended previous validation studies of a new targeted NGS panel to include the detection of copy number amplifications (CNAs), fusions, and exon skipping variants. Detect
Externí odkaz:
https://doaj.org/article/cc965d9bf42b4d178be891be87e839f8
Autor:
Ubaradka G. Sathyanarayana, Kristina Koch, Hestia Mellert, Samantha Cooper, Trudi Foreman, Paula Stonemetz, Scott Thurston, Westen Hahn, Jakkie Greer, Dawne N. Shelton, Dianna Maar, Leisa Jackson, Nicholas F. Dupuis, Gary Pestano, Amanda Weaver
Publikováno v:
The Journal of Molecular Diagnostics. 19:404-416
Nearly 80% of cancer patients do not have genetic mutation results available at initial oncology consultation; up to 25% of patients begin treatment before receiving their results. These factors hinder the ability to pursue optimal treatment strategi
Autor:
John D. Minna, Prakash Makarla, Victor Stastny, Lin Li, Ziding Feng, Makoto Suzuki, Kuntal Majmudar, Adi F. Gazdar, Ubaradka G. Sathyanarayana, Angela Yen Moore, Asha Padar
Publikováno v:
Cancer letters. 432
Autor:
Ubaradka G. Sathyanarayana, Ashley M Santa-Cruz, Karl Garsha, Theresa Y. MacDonald, Naoki Kitabayashi, Mark A. Rubin, Francesca Demichelis, Gary Pestano, Christopher J. LaFargue, Ashutosh K. Tewari, Dea Nagy, Jerry W. Kosmeder, Janice Riley, Chol S Yun, Maria A. Svensson, Dorothee Pflueger
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Prostate cancer is a clinically heterogeneous and multifocal disease. More than 80% of patients with prostate cancer harbor multiple geographically discrete cancer foci at the time of diagnosis. Emerging data suggest that these foci are molecularly d
Autor:
Isis C. Sroka, Gerald D. Pond, Raymond B. Nagle, Frank Porreca, Tamara King, Gary Pestano, Bernard W. Futscher, Jaime M. Gard, Janice Riley, Ubaradka G. Sathyanarayana, Anne E. Cress
Publikováno v:
The Open Prostate Cancer Journal. 2:59-66
Existing clinical imaging procedures lack sensitivity and specificity in detecting early prostate cancer bone me- tastatic lesions. In this study, we developed a highly reproducible bone metastasis xenograft model and identified possible molecular im
Autor:
Ziding Feng, Adi F. Gazdar, John D. Minna, Lin Li, Kuntal Majmudar, Prakash Makarla, Victor Stastny, Ubaradka G. Sathyanarayana, Angela Yen Moore, Asha Padar, Makoto Suzuki
Publikováno v:
Cancer Letters. 245:112-120
We investigated the aberrant promoter methylation status of 12 genes in skin lesions, both malignant (basal cell carcinomas (BCCs), n=68 and squamous cell carcinomas (SCCs), n=35) and non-malignant (tags, n=58) skin lesions and compared the results o
Autor:
Tomasz Tuziak, Dong Sup Yoon, H. B. Grossman, Joon Jeong, Adi F. Gazdar, Ubaradka G. Sathyanarayana, Tadeusz Majewski, Steven E. Scherer, Tang C. Kuang, Dennis A. Johnston, Jain Hua Zhou, Bogdan Czerniak, Mi Sook Kim, Jun Zhi Li, Ruo Dan Zhang, William F. Benedict, Konrad Ptaszyński, Andrzej Kram
Publikováno v:
Laboratory Investigation. 86:175-190
In this paper, we present whole-organ histologic and genetic mapping studies using hypervariable DNA markers on chromosome 13 and then integrate the recombination- and single-nucleotide polymorphic sites (SNPs)-based deletion maps with the annotated
Autor:
Takehiko Fujisawa, Ubaradka G. Sathyanarayana, Takao Takahashi, Narayan Shivapurkar, Toshihiko Iizasa, Makoto Suzuki, Hisayuki Shigematsu, Adi F. Gazdar
Publikováno v:
Lung Cancer. 47:309-314
Deregulation of cell cycle inhibition contributes to human carcinogenesis. Reprimo (for stop/repress) is a newly identified mediator of the p53-mediated cell cycle arrest at the G2 phase. Loss of Reprimo expression due to promoter methylation was rec
Autor:
Hisayuki Shigematsu, Ubaradka G. Sathyanarayana, Takao Takahashi, Narayan Shivapurkar, Adi F. Gazdar, Jyotsna Reddy, Makoto Suzuki, Kuniharu Miyajima
Publikováno v:
Chest. 125:97S-101S
Despite major improvements in patient management, the prognosis for patients with lung cancer remains dismal. As our knowledge of the molecular biology of cancers has increased, new targets for therapeutic interventions have been identified. In this
Autor:
Asha Padar, Adi F. Gazdar, Arthur I. Sagalowsky, Bogdan Czerniak, H. Barton Grossman, Ubaradka G. Sathyanarayana, Jolanta Bondaruk, Makoto Suzuki, John D. Minna, Eugene P. Frenkel, Riichiroh Maruyama
Publikováno v:
Cancer Research. 64:1425-1430
Laminin-5 (LN5) anchors epithelial cells to the underlying basement membrane, and it is encoded by three distinct genes: LAMA3, LAMB3, and LAMC2. To metastasize and grow, cancer cells must invade and destroy the basement membrane. Our previous work h