Výsledky vyhledávání - "Ubaidullah Baryar"

Identification of core allosteric sites through temperature- and nucleus-invariant chemical shift covariance

Autor: Hebatallah Mohamed, Ubaidullah Baryar, Amir Bashiri, Rajeevan Selvaratnam, Bryan VanSchouwen, Giuseppe Melacini

Publikováno v: Biophys J

Allosteric regulation is essential to control biological function. In addition, allosteric sites offer a promising venue for selective drug targeting. However, accurate mapping of allosteric sites remains challenging since allostery relies on often s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a5b93aa1a71d51a76ffc9fa27e2f53
https://pubmed.ncbi.nlm.nih.gov/35538664

Zobrazit plný text záznamu

Divergent Allostery Reveals Critical Differences between Structurally Homologous Regulatory Domains of Plasmodium Falciparum and Human Protein Kinase G

Autor: Jung Ah Byun, Bryan VanSchouwen, Jinfeng Huang, Ubaidullah Baryar, Giuseppe Melacini

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c2627b3bab9f3edf885d75d2999c3b7
https://doi.org/10.2139/ssrn.3962715

Zobrazit plný text záznamu

Divergent allostery reveals critical differences between structurally homologous regulatory domains of Plasmodium falciparum and human protein kinase G

Autor: Jung Ah Byun, Bryan VanSchouwen, Jinfeng Huang, Ubaidullah Baryar, Giuseppe Melacini

Publikováno v: Journal of Biological Chemistry. 298:101691

Malaria is a life-threatening infectious disease primarily caused by the Plasmodium falciparum parasite. The increasing resistance to current antimalarial drugs and their side effects has led to an urgent need for novel malaria drug targets, such as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9444104e67b6e1ef42681d490cd99836
https://doi.org/10.1016/j.jbc.2022.101691

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání